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PF3D7_1239600 hydroxyethylthiazole kinase [ Plasmodium falciparum 3D7 ]

Gene ID: 811436, updated on 17-May-2024

Summary

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Gene symbol
PF3D7_1239600
Gene description
hydroxyethylthiazole kinase
Primary source
PlasmoDB:PF3D7_1239600
Locus tag
PF3D7_1239600
Gene type
protein coding
RNA name
hydroxyethylthiazole kinase
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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Genomic context

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See PF3D7_1239600 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
1
Sequence:
Chromosome: 12; NC_037284.1 (1652936..1653844, complement)

Chromosome 12 - NC_037284.1Genomic Context describing neighboring genes Neighboring gene conserved protein, unknown function Neighboring gene DNA gyrase subunit B Neighboring gene ATP-dependent zinc metalloprotease FTSH 1 Neighboring gene conserved Plasmodium protein, unknown function

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037284.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Isolation, characterization, interaction of a thiazolekinase (Plasmodium falciparum) with silver nanoparticles. Yao J, et al. Int J Biol Macromol, 2015 Aug. PMID 26049116
  2. Sequence of Plasmodium falciparum chromosomes 2, 10, 11 and 14. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368868
  3. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Plasmodium falciparum thiazolekinase has been cloned and characterized.
    Title: Isolation, characterization, interaction of a thiazolekinase (Plasmodium falciparum) with silver nanoparticles.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by GeneDB

Function Evidence Code Pubs
enables hydroxyethylthiazole kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within thiamine biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxyethylthiazole kinase
XP_001350790.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_037284.1 Reference assembly

    Range
    1652936..1653844 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001350754.1 → XP_001350790.1  hydroxyethylthiazole kinase [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_001350790.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A024V5A3, A0A024VMI8, A0A024W3X0, A0A024WM19, A0A024X3U0, A0A0L0CUZ8, A0A0L1I9T4, A0A0L7KH75, A0A0L7M6U3, Q8I527, W4ICZ8, W4J227, W7F943, W7G1G4, W7JJT2, W7JRC8
    Conserved Domains (1) summary
    cd01170
    Location:33 → 282
    THZ_kinase; 4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine ...
Nucleotide Protein
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