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PF3D7_1420600 pantothenate kinase 1, putative [ Plasmodium falciparum 3D7 ]

Gene ID: 811781, updated on 16-Oct-2023

Summary

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Gene symbol
PF3D7_1420600
Gene description
pantothenate kinase 1, putative
Locus tag
PF3D7_1420600
Gene type
protein coding
RNA name
pantothenate kinase 1, putative
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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Genomic context

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Location:
chromosome: 14
Exon count:
3
Sequence:
Chromosome: 14; NC_037283.1 (854094..855963, complement)

Chromosome 14 - NC_037283.1Genomic Context describing neighboring genes Neighboring gene glycine--tRNA ligase Neighboring gene protein GPR89, putative Neighboring gene surface protein P113 Neighboring gene dynein light chain, putative

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037283.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of Plasmodium falciparum Pantothenate Kinase and Identification of Its Inhibitors From Natural Products. Nurkanto A, et al. Front Cell Infect Microbiol, 2021. PMID 33768012, Free PMC Article
  2. Structure-activity analysis of CJ-15,801 analogues that interact with Plasmodium falciparum pantothenate kinase and inhibit parasite proliferation. Spry C, et al. Eur J Med Chem, 2018 Jan 1. PMID 29233590
  3. A novel heteromeric pantothenate kinase complex in apicomplexan parasites. Tjhin ET, et al. PLoS Pathog, 2021 Jul. PMID 34324601, Free PMC Article
  4. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by GeneDB

Function Evidence Code Pubs
enables 14-3-3 protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables pantothenate kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within coenzyme A biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within response to xenobiotic stimulus IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
pantothenate kinase 1, putative
XP_001348373.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_037283.1 Reference assembly

    Range
    854094..855963 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001348337.2 → XP_001348373.2  pantothenate kinase 1, putative [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_001348373.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2I0C1U5, Q8ILP4, W4IUU3, W7FLG8
    Conserved Domains (1) summary
    cl17037
    Location:21 → 515
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
Nucleotide Protein
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