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PF3D7_1443700 dephospho-CoA kinase, putative [ Plasmodium falciparum 3D7 ]

Gene ID: 811997, updated on 16-Oct-2023

Summary

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Gene symbol
PF3D7_1443700
Gene description
dephospho-CoA kinase, putative
Locus tag
PF3D7_1443700
Gene type
protein coding
RNA name
dephospho-CoA kinase, putative
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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Genomic context

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Location:
chromosome: 14
Exon count:
2
Sequence:
Chromosome: 14; NC_037283.1 (1791911..1793004, complement)

Chromosome 14 - NC_037283.1Genomic Context describing neighboring genes Neighboring gene poly(A)-specific ribonuclease PARN, putative Neighboring gene gamma-tubulin complex component, putative Neighboring gene pre-mRNA-splicing factor CWC24, putative Neighboring gene heat shock protein 90, putative

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037283.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dephospho-CoA kinase, a nuclear-encoded apicoplast protein, remains active and essential after Plasmodium falciparum apicoplast disruption. Swift RP, et al. EMBO J, 2021 Aug 16. PMID 34031901, Free PMC Article
  2. Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites. Boucher MJ, et al. PLoS Biol, 2018 Sep. PMID 30212465, Free PMC Article
  3. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Dephospho-CoA kinase, a nuclear-encoded apicoplast protein, remains active and essential after Plasmodium falciparum apicoplast disruption.
    Title: Dephospho-CoA kinase, a nuclear-encoded apicoplast protein, remains active and essential after Plasmodium falciparum apicoplast disruption.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by GeneDB

Function Evidence Code Pubs
enables dephospho-CoA kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within coenzyme A biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in apicoplast HDA PubMed 
located_in apicoplast IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
dephospho-CoA kinase, putative
XP_001348589.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_037283.1 Reference assembly

    Range
    1791911..1793004 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001348553.1 → XP_001348589.1  dephospho-CoA kinase, putative [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_001348589.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A024V083, A0A024VKQ0, A0A024W184, A0A024WJB9, A0A024WYX8, A0A0L7KA27, Q8IL34, W4I9M2, W4IXL1, W7FE78, W7FM72, W7JQL1, W7JWP0
    Conserved Domains (1) summary
    cd02022
    Location:74 → 256
    DPCK; Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis.
Nucleotide Protein
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