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PMP1 proteolipid ATPase [ Saccharomyces cerevisiae S288C ]

Gene ID: 850389, updated on 17-May-2024

Summary

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Gene symbol
PMP1
Gene description
proteolipid ATPase
Primary source
FungiDB:YCR024C-A
Locus tag
YCR024C-A
See related
SGD:S000000619; AllianceGenome:SGD:S000000619
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables enzyme regulator activity. Involved in positive regulation of ATPase activity. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_001135.5 (162945..163067, complement)

Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene asparagine--tRNA ligase SLM5 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene nucleotide diphosphatase/phosphodiesterase NPP1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001135.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The 3'-UTR mediates the cellular localization of an mRNA encoding a short plasma membrane protein. Loya A, et al. RNA, 2008 Jul. PMID 18492794, Free PMC Article
  2. Single-spanning membrane protein insertion in membrane mimetic systems: role and localization of aromatic residues. Coïc YM, et al. Eur Biophys J, 2005 Dec. PMID 16025323
  3. Deciphering the role of individual acyl chains in the interaction network between phosphatidylserines and a single-spanning membrane protein. Mousson F, et al. Biochemistry, 2002 Nov 19. PMID 12427022
  4. PMP1 18-38, a yeast plasma membrane protein fragment, binds phosphatidylserine from bilayer mixtures with phosphatidylcholine: a (2)H-NMR study. Roux M, et al. Biophys J, 2000 Nov. PMID 11053135, Free PMC Article
  5. Development of a Synthetic Malonyl-CoA Sensor in Saccharomyces cerevisiae for Intracellular Metabolite Monitoring and Genetic Screening. Li S, et al. ACS Synth Biol, 2015 Dec 18. PMID 26149896

See all (38) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Study found involvement of the 3'-UTR in the localization of an mRNA that encodes a very short Saccharomyces cerevisiae protein (Pmp1).
    Title: The 3'-UTR mediates the cellular localization of an mRNA encoding a short plasma membrane protein.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables enzyme regulator activity IEA
Inferred from Electronic Annotation
more info
  
enables enzyme regulator activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of ATP-dependent activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IGI
Inferred from Genetic Interaction
more info
 PubMed 

General protein information

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Preferred Names
proteolipid ATPase
NP_058137.1
  • Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p; small single-membrane span proteolipid; forms unique helix and positively charged cytoplasmic domain that is able to specifically segregate phosphatidylserines; PMP1 has a paralog, PMP2, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001135.5 Reference assembly

    Range
    162945..163067 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178739.1 → NP_058137.1  TPA: proteolipid ATPase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_058137.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VR35, P32903, Q76PA9
    UniProtKB/TrEMBL
    A0A8H4F932, A6ZTK6, B3LU96, C7GW71, C8Z4B5, G2WA43, N1P9A5
    Conserved Domains (1) summary
    pfam08114
    Location:2 → 40
    PMP1_2; ATPase proteolipid family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P32903.1

Gene LinkOut

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