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GAS2 1,3-beta-glucanosyltransferase [ Saccharomyces cerevisiae S288C ]

Gene ID: 851056, updated on 13-Apr-2024

Summary

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Gene symbol
GAS2
Gene description
1,3-beta-glucanosyltransferase
Primary source
SGD:S000004335
Locus tag
YLR343W
See related
AllianceGenome:SGD:S000004335
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables 1,3-beta-glucanosyltransferase activity. Involved in ascospore wall assembly and fungal-type cell wall beta-glucan biosynthetic process. Located in fungal-type vacuole. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (816094..817761)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene 1,3-beta-D-glucan synthase Neighboring gene uncharacterized protein Neighboring gene tRNA-Arg Neighboring gene ribosomal 60S subunit protein L26A

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001144.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Trapped Covalent Intermediate of a Glycoside Hydrolase on the Pathway to Transglycosylation. Insights from Experiments and Quantum Mechanics/Molecular Mechanics Simulations. Raich L, et al. J Am Chem Soc, 2016 Mar 16. PMID 26859322
  2. Molecular mechanisms of yeast cell wall glucan remodeling. Hurtado-Guerrero R, et al. J Biol Chem, 2009 Mar 27. PMID 19097997, Free PMC Article
  3. Disulfide bond structure and domain organization of yeast beta(1,3)-glucanosyltransferases involved in cell wall biogenesis. Popolo L, et al. J Biol Chem, 2008 Jul 4. PMID 18468997
  4. GAS2 and GAS4, a pair of developmentally regulated genes required for spore wall assembly in Saccharomyces cerevisiae. Ragni E, et al. Eukaryot Cell, 2007 Feb. PMID 17189486, Free PMC Article
  5. The Dual Activity Responsible for the Elongation and Branching of β-(1,3)-Glucan in the Fungal Cell Wall. Aimanianda V, et al. mBio, 2017 Jun 20. PMID 28634239, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables 1,3-beta-glucanosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 1,3-beta-glucanosyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables glucanosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in ascospore wall assembly IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in ascospore wall assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cell wall organization IEA
Inferred from Electronic Annotation
more info
  
involved_in cellular component organization or biogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in fungal-type cell wall beta-glucan biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in fungal-type cell wall organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in fungal-type cell wall organization or biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in fungal-type vacuole HDA PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in side of membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
1,3-beta-glucanosyltransferase
NP_013447.1
  • 1,3-beta-glucanosyltransferase; involved with Gas4p in spore wall assembly; has similarity to Gas1p

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    816094..817761
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182232.1 → NP_013447.1  TPA: 1,3-beta-glucanosyltransferase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013447.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VYY2, Q06135
    UniProtKB/TrEMBL
    G2WJG2, N1P1N2
    Conserved Domains (2) summary
    pfam03198
    Location:25 → 344
    Glyco_hydro_72; Glucanosyltransferase
    pfam07983
    Location:397 → 473
    X8; X8 domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
5O9O_A.1
5O9P_A.1
5O9Q_A.1
5O9R_A.1
5O9Y_A.1
5OA2_A.1
5OA2_B.1
5OA2_C.1
5OA6_A.1
Q06135.1

Gene LinkOut

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