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TRP4 anthranilate phosphoribosyltransferase [ Saccharomyces cerevisiae S288C ]

Gene ID: 851956, updated on 13-Apr-2024

Summary

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Gene symbol
TRP4
Gene description
anthranilate phosphoribosyltransferase
Primary source
SGD:S000002762
Locus tag
YDR354W
See related
AllianceGenome:SGD:S000002762
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables anthranilate phosphoribosyltransferase activity. Involved in tryptophan biosynthetic process. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (1184747..1185889)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Ypq2p Neighboring gene thioredoxin-disulfide reductase TRR1 Neighboring gene Spc110p Neighboring gene Cnl1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Replacement of the yeast TRP4 3' untranslated region by a hammerhead ribozyme results in a stable and efficiently exported mRNA that lacks a poly(A) tail. Düvel K, et al. RNA, 2002 Mar. PMID 12003493, Free PMC Article
  2. Sequence requirements of the bidirectional yeast TRP4 mRNA 3'-end formation signal. Egli CM, et al. Nucleic Acids Res, 1997 Jan 15. PMID 9016573, Free PMC Article
  3. Regulation of the TRP4 gene of Saccharomyces cerevisiae at the transcriptional level and functional analysis of its promotor. Furter R, et al. Mol Gen Genet, 1988 Jan. PMID 3278195
  4. Interpathway regulation of the TRP4 gene of yeast. Braus G, et al. EMBO J, 1989 Mar. PMID 2656261, Free PMC Article
  5. The TRP4 gene of Saccharomyces cerevisiae: isolation and structural analysis. Furter R, et al. Nucleic Acids Res, 1986 Aug 26. PMID 2428012, Free PMC Article

See all (49) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables anthranilate phosphoribosyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables anthranilate phosphoribosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in tryptophan biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tryptophan biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in tryptophan biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus HDA PubMed 

General protein information

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Preferred Names
anthranilate phosphoribosyltransferase
NP_010641.3
  • Anthranilate phosphoribosyl transferase; transferase of the tryptophan biosynthetic pathway; catalyzes the phosphoribosylation of anthranilate; subject to the general control system of amino acid biosynthesis

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    1184747..1185889
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180662.3 → NP_010641.3  TPA: anthranilate phosphoribosyltransferase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010641.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VSY4, P07285
    UniProtKB/TrEMBL
    A0A6A5PZ12, A6ZYV4, B3LFU7, B5VGN6, C7GMI0, C8Z5R5, G2WB92, N1P8P9
    Conserved Domains (1) summary
    COG0547
    Location:3 → 379
    TrpD; Anthranilate phosphoribosyltransferase [Amino acid transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P07285.1

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