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TRP5 tryptophan synthase TRP5 [ Saccharomyces cerevisiae S288C ]

Gene ID: 852858, updated on 13-Apr-2024

Summary

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Gene symbol
TRP5
Gene description
tryptophan synthase TRP5
Primary source
SGD:S000002994
Locus tag
YGL026C
See related
AllianceGenome:SGD:S000002994
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables tryptophan synthase activity. Involved in tryptophan biosynthetic process. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (446412..448535, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene putative glucan endo-1,3-beta-D-glucosidase Neighboring gene mannosyl-oligosaccharide glucosidase Neighboring gene Pgd1p Neighboring gene Pib2p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TRYPTOPHAN SYNTHETASE MUTANTS OF YEAST: ACTION OF A SUPER-SUPPRESSOR IN RELATION TO ALLELIC MAPPING AND COMPLEMENTATION. UCRL-11191. MANNEY TR. UCRL US At Energy Comm, 1964 Jan 8. PMID 24547113
  2. Saccharomyces cerevisiae genes involved in survival of heat shock. Jarolim S, et al. G3 (Bethesda), 2013 Dec 9. PMID 24142923, Free PMC Article
  3. Characterization of the trp5-27 allele used to monitor drug-induced mitotic gene conversion in the Saccharomyces cerevisiae tester strain D7. Ehrenhofer-Murray AE, et al. Mutagenesis, 1994 Jul. PMID 7968581
  4. Purification and properties of tryptophan synthase from baker's yeast (Saccharomyces cerevisiae). Bailey CJ, et al. Biochem J, 1983 Jan 1. PMID 6342605, Free PMC Article
  5. Yeast gene TRP5: structure, function, regulation. Zalkin H, et al. J Biol Chem, 1982 Feb 10. PMID 6276387

See all (77) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables tryptophan synthase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables tryptophan synthase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in tryptophan biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tryptophan biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in tryptophan biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus HDA PubMed 

General protein information

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Preferred Names
tryptophan synthase TRP5
NP_011489.1
  • Tryptophan synthase; catalyzes the last step of tryptophan biosynthesis; regulated by the general control system of amino acid biosynthesis

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    446412..448535 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180891.1 → NP_011489.1  TPA: tryptophan synthase TRP5 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011489.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUB2, P00931
    UniProtKB/TrEMBL
    A0A8H4FBM2, B3LIN9, C8Z8L6, N1P5K3
    Conserved Domains (2) summary
    PRK04346
    Location:305 → 688
    PRK04346; tryptophan synthase subunit beta; Validated
    pfam00290
    Location:9 → 259
    Trp_syntA; Tryptophan synthase alpha chain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P00931.1

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