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PGU1 endo-polygalacturonase [ Saccharomyces cerevisiae S288C ]

Gene ID: 853618, updated on 17-May-2024

Summary

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Gene symbol
PGU1
Gene description
endo-polygalacturonase
Primary source
FungiDB:YJR153W
Locus tag
YJR153W
See related
SGD:S000003914; AllianceGenome:SGD:S000003914
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
PGL1; PSM1
Summary
Enables polygalacturonase activity. Involved in pectin catabolic process. Located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (722815..723900)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene allantoate permease Neighboring gene uncharacterized protein Neighboring gene putative aryl-alcohol dehydrogenase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001142.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Use of the Saccharomyces cerevisiae endopolygalacturonase promoter to direct expression in Escherichia coli. Gognies S, et al. J Ind Microbiol Biotechnol, 2012 Jul. PMID 22366768
  2. Comparative characterization of endo-polygalacturonase (Pgu1) from Saccharomyces cerevisiae and Saccharomyces paradoxus under winemaking conditions. Eschstruth A, et al. Appl Microbiol Biotechnol, 2011 Aug. PMID 21479715
  3. Epigenetic regulation of PGU1 transcription in Saccharomyces cerevisiae. Louw C, et al. FEMS Yeast Res, 2010 Mar. PMID 20074297
  4. Endo-polygalacturonase in Saccharomyces wine yeasts: effect of carbon source on enzyme production. Radoi F, et al. FEMS Yeast Res, 2005 Apr. PMID 15780666
  5. Evaluation of polygalacturonase activity in Saccharomyces cerevisiae wine strains. Fernández-González M, et al. FEMS Microbiol Lett, 2004 Aug 15. PMID 15321671

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Overexpressing the PGU1 gene of S. paradoxus or S. cerevisiae did not make much difference, showing that the higher activity of S. paradoxus strains could be due to a different regulation mechanism rather than to a different sequence of PGU1.
    Title: Comparative characterization of endo-polygalacturonase (Pgu1) from Saccharomyces cerevisiae and Saccharomyces paradoxus under winemaking conditions.
  2. The results of this study suggest that PGU1 is silenced by being folded into a heterochromatin-like structure at its subtelomeric position on chromosome X.
    Title: Epigenetic regulation of PGU1 transcription in Saccharomyces cerevisiae.
  3. Expression of PGU1 was found to be determined by the transcription level of its two transcription factors TEC1 and STE12.
    Title: Regulation of endo-polygalacturonase activity in Saccharomyces cerevisiae.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
  
enables polygalacturonase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables polygalacturonase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables polygalacturonase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in cell wall organization IEA
Inferred from Electronic Annotation
more info
  
involved_in pectin catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in pectin catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in pectin catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in extracellular region IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular region IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
endo-polygalacturonase
NP_012687.3
  • Endo-polygalacturonase; pectolytic enzyme that hydrolyzes the alpha-1,4-glycosidic bonds in the rhamnogalacturonan chains in pectins

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    722815..723900
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181811.3 → NP_012687.3  TPA: endo-polygalacturonase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012687.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VWX2, E9P8V0, P47180
    UniProtKB/TrEMBL
    A0A024BTY8, A0A8H4BYY5, A6ZQB1, B3LQN3, C8ZBV3, N1P1C5
    Conserved Domains (1) summary
    pfam00295
    Location:43 → 361
    Glyco_hydro_28; Glycosyl hydrolases family 28
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P47180.1

Gene LinkOut

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