U.S. flag

An official website of the United States government

IMA2 oligo-1,6-glucosidase IMA2 [ Saccharomyces cerevisiae S288C ]

Gene ID: 854008, updated on 4-Jan-2025

Summary

Official Symbol
IMA2
Official Full Name
oligo-1,6-glucosidase IMA2
Primary source
SGD:S000005517
Locus tag
YOL157C
See related
AllianceGenome:SGD:S000005517; FungiDB:YOL157C; VEuPathDB:YOL157C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables oligo-1,6-glucosidase activity and sucrose alpha-glucosidase activity. Involved in disaccharide catabolic process. Human ortholog(s) of this gene implicated in cystinuria. Orthologous to human SLC3A1 (solute carrier family 3 member 1). [provided by Alliance of Genome Resources, Jan 2025]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See IMA2 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (22525..24294, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Css3p Neighboring gene Enb1p Neighboring gene hexose transporter HXT11 Neighboring gene uncharacterized protein

Interactions

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables alpha-1,4-glucosidase activity  
enables alpha-amylase activity  
enables glucan 1,4-alpha-maltotriohydrolase activity  
enables hydrolase activity, acting on glycosyl bonds  
enables oligo-1,6-glucosidase activity  
enables oligo-1,6-glucosidase activity PubMed 
enables oligo-1,6-glucosidase activity  
enables oligo-1,6-glucosidase activity PubMed 
enables sucrose alpha-glucosidase activity  
enables sucrose alpha-glucosidase activity PubMed 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process  
involved_in disaccharide catabolic process  
involved_in disaccharide catabolic process PubMed 
involved_in maltose catabolic process  
involved_in maltose metabolic process  
involved_in sucrose catabolic process  
Component Evidence Code Pubs
is_active_in cellular_component  

General protein information

Preferred Names
oligo-1,6-glucosidase IMA2
NP_014485.1
  • Isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase); preferred specificity for isomaltose, alpha-methylglucoside, and palatinose, but also exhibits alpha-1,2 glucosidase activity on sucrose and kojibiose, and can cleave the 1,3-alpha linkage of nigerose and turanose and the alpha-1,5 linkage of leucrose in vitro; not required for isomaltose utilization, but Ima2p overexpression allows the ima1 null mutant to grow on isomaltose

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    22525..24294 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183410.1NP_014485.1  TPA: oligo-1,6-glucosidase IMA2 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014485.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W1R3, Q08295
    UniProtKB/TrEMBL
    A6ZPM1, B3LIR3, C8ZB00, E1AFY7, G2WM79
    Conserved Domains (2) summary
    cd11333
    Location:16503
    AmyAc_SI_OligoGlu_DGase; Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins
    pfam16657
    Location:514585
    Malt_amylase_C; Maltogenic Amylase, C-terminal domain
External link. Please review our privacy policy.