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ATF1 alcohol O-acetyltransferase [ Saccharomyces cerevisiae S288C ]

Gene ID: 854559, updated on 13-Apr-2024

Summary

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Gene symbol
ATF1
Gene description
alcohol O-acetyltransferase
Primary source
SGD:S000005904
Locus tag
YOR377W
See related
AllianceGenome:SGD:S000005904
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables alcohol O-acetyltransferase activity. Involved in acetate ester metabolic process involved in fermentation. Located in lipid droplet. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (1046226..1047803)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Amf1p Neighboring gene Rdr1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Increased Acetate Ester Production of Polyploid Industrial Brewer's Yeast Strains via Precise and Seamless "Self-cloning" Integration Strategy. Dong J, et al. Iran J Biotechnol, 2019 Apr. PMID 31457054, Free PMC Article
  2. Improving the Organoleptic Properties of a Craft Mezcal Beverage by Increasing Fatty Acid Ethyl Ester Contents through ATF1 Expression in an Engineered Kluyveromyces marxianus UMPe-1 Yeast. Campos-García J, et al. J Agric Food Chem, 2018 May 2. PMID 29644852
  3. Saccharomyces cerevisiae Atf1p is an alcohol acetyltransferase and a thioesterase in vitro. Nancolas B, et al. Yeast, 2017 Jun. PMID 28160314, Free PMC Article
  4. The fungal aroma gene ATF1 promotes dispersal of yeast cells through insect vectors. Christiaens JF, et al. Cell Rep, 2014 Oct 23. PMID 25310977
  5. Production of the aroma chemicals 3-(methylthio)-1-propanol and 3-(methylthio)-propylacetate with yeasts. Etschmann MM, et al. Appl Microbiol Biotechnol, 2008 Sep. PMID 18597084

See all (65) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables N-acetyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables alcohol O-acetyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables alcohol O-acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables fatty acyl-CoA hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in acetate ester metabolic process involved in fermentation IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in acetate ester metabolic process involved in fermentation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum HDA PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in lipid droplet IDA
Inferred from Direct Assay
more info
 PubMed 
located_in lipid droplet IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
alcohol O-acetyltransferase
NP_015022.3
  • Alcohol acetyltransferase; responsible for the major part of volatile acetate ester production during fermentation; main enzyme involved in terpenyl acetate synthesis; potential roles in lipid and sterol metabolism

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    1046226..1047803
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183797.3 → NP_015022.3  TPA: alcohol O-acetyltransferase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015022.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W370, P40353, Q08901
    UniProtKB/TrEMBL
    A0A5J6SG86, A0A5J6SGW0, A0A5J6SGW7, A0A5J6SKC0, A6ZPK5, B3LK31, B5VSQ1, C7GVG9, C8ZHC6, N1NWA4
    Conserved Domains (1) summary
    pfam07247
    Location:28 → 522
    AATase; Alcohol acetyltransferase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40353.2

Gene LinkOut

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