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YMR084W putative glutamine--fructose-6-phosphate transaminase [ Saccharomyces cerevisiae S288C ]

Gene ID: 855108, updated on 11-Apr-2024

Summary

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Gene symbol
YMR084W
Gene description
putative glutamine--fructose-6-phosphate transaminase
Primary source
SGD:S000004689
Locus tag
YMR084W
See related
AllianceGenome:SGD:S000004689
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable glutamine-fructose-6-phosphate transaminase (isomerizing) activity. Predicted to be involved in several processes, including UDP-N-acetylglucosamine metabolic process; fructose 6-phosphate metabolic process; and fungal-type cell wall chitin biosynthetic process. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 12 and obesity. Orthologous to human GFPT1 (glutamine--fructose-6-phosphate transaminase 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (436628..437416)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene alcohol dehydrogenase ADH3 Neighboring gene uncharacterized protein Neighboring gene Seg1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequencing and comparison of yeast species to identify genes and regulatory elements. Kellis M, et al. Nature, 2003 May 15. PMID 12748633
  2. Bayesian modeling of the yeast SH3 domain interactome predicts spatiotemporal dynamics of endocytosis proteins. Tonikian R, et al. PLoS Biol, 2009 Oct. PMID 19841731, Free PMC Article
  3. The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII. Bowman S, et al. Nature, 1997 May 29. PMID 9169872
  4. The 4E-BP Caf20p Mediates Both eIF4E-Dependent and Independent Repression of Translation. Castelli LM, et al. PLoS Genet, 2015 May. PMID 25973932, Free PMC Article
  5. A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast. Carey SB, et al. G3 (Bethesda), 2023 Jan 12. PMID 36409020, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables glutamine-fructose-6-phosphate transaminase (isomerizing) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glutamine-fructose-6-phosphate transaminase (isomerizing) activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables transaminase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in UDP-N-acetylglucosamine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in UDP-N-acetylglucosamine metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in biological_process ND
No biological Data available
more info
  
involved_in fructose 6-phosphate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in fungal-type cell wall chitin biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glutamine metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in protein N-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
putative glutamine--fructose-6-phosphate transaminase
NP_013801.1
  • hypothetical protein; YMR084W and adjacent ORF YMR085W are merged in related strains, and together are paralogous to glutamine-fructose-6-phosphate amidotransferase GFA1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    436628..437416
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182583.1 → NP_013801.1  TPA: putative glutamine--fructose-6-phosphate transaminase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013801.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A2P2R3, D6VZQ7, E9P8R5, Q3E7C0, Q6B308, Q6WV01
    UniProtKB/TrEMBL
    A0A6V8S5F2, G2WKD1
    Conserved Domains (1) summary
    COG0449
    Location:1 → 262
    GlmS; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains [Cell wall/membrane/envelope biogenesis]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2P2R3.1

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