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YMR085W uncharacterized protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 855109, updated on 27-Jan-2024

Summary

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Gene symbol
YMR085W
Gene description
uncharacterized protein
Primary source
SGD:S000004690
Locus tag
YMR085W
See related
AllianceGenome:SGD:S000004690
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable glutamine-fructose-6-phosphate transaminase (isomerizing) activity. Predicted to be involved in several processes, including UDP-N-acetylglucosamine metabolic process; fructose 6-phosphate metabolic process; and fungal-type cell wall chitin biosynthetic process. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 12 and obesity. Orthologous to human GFPT1 (glutamine--fructose-6-phosphate transaminase 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (437491..438789)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene alcohol dehydrogenase ADH3 Neighboring gene putative glutamine--fructose-6-phosphate transaminase Neighboring gene Seg1p Neighboring gene putative ADP-ribose 1''-phosphate phosphatase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequencing and comparison of yeast species to identify genes and regulatory elements. Kellis M, et al. Nature, 2003 May 15. PMID 12748633
  2. Modulation of Ubc4p/Ubc5p-mediated stress responses by the RING-finger-dependent ubiquitin-protein ligase Not4p in Saccharomyces cerevisiae. Mulder KW, et al. Genetics, 2007 May. PMID 17513889, Free PMC Article
  3. αβ'-NAC cooperates with Sam37 to mediate early stages of mitochondrial protein import. Ponce-Rojas JC, et al. FEBS J, 2017 Mar. PMID 28109174
  4. The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII. Bowman S, et al. Nature, 1997 May 29. PMID 9169872
  5. A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast. Carey SB, et al. G3 (Bethesda), 2023 Jan 12. PMID 36409020, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables carbohydrate derivative binding IEA
Inferred from Electronic Annotation
more info
  
enables glutamine-fructose-6-phosphate transaminase (isomerizing) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in UDP-N-acetylglucosamine metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in biological_process ND
No biological Data available
more info
  
involved_in carbohydrate derivative metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in fructose 6-phosphate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in fungal-type cell wall chitin biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein N-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
uncharacterized protein
NP_013802.1
  • hypothetical protein; YMR085W and adjacent ORF YMR084W are merged in related strains, and together are paralogous to glutamine-fructose-6-phosphate amidotransferase GFA1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    437491..438789
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182584.1 → NP_013802.1  TPA: uncharacterized protein YMR085W [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013802.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    C8ZET8, D6VZQ8, P0CF18
    UniProtKB/TrEMBL
    A0A6V8S4S6, G2WKD2
    Conserved Domains (1) summary
    COG0449
    Location:2 → 428
    GlmS; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains [Cell wall/membrane/envelope biogenesis]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0CF18.1

Gene LinkOut

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