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LYP1 lysine permease [ Saccharomyces cerevisiae S288C ]

Gene ID: 855453, updated on 25-Apr-2024

Summary

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Gene symbol
LYP1
Gene description
lysine permease
Primary source
SGD:S000005212
Locus tag
YNL268W
See related
AllianceGenome:SGD:S000005212
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables basic amino acid transmembrane transporter activity. Involved in basic amino acid transport. Located in eisosome. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (138550..140385)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene arginine permease ALP1 Neighboring gene Bsc4p Neighboring gene 1-phosphatidylinositol 4-kinase Neighboring gene Ist1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Membrane Lipid Requirements of the Lysine Transporter Lyp1 from Saccharomyces cerevisiae. van 't Klooster JS, et al. J Mol Biol, 2020 Jun 26. PMID 32413406, Free PMC Article
  2. Extracellular loops matter - subcellular location and function of the lysine transporter Lyp1 from Saccharomyces cerevisiae. Van't Klooster JS, et al. FEBS J, 2020 Oct. PMID 32096906, Free PMC Article
  3. Disentangling strictly self-serving mutations from win-win mutations in a mutualistic microbial community. Hart SFM, et al. Elife, 2019 Jun 4. PMID 31162049, Free PMC Article
  4. Asymmetry in inward- and outward-affinity constant of transport explain unidirectional lysine flux in Saccharomyces cerevisiae. Bianchi F, et al. Sci Rep, 2016 Aug 23. PMID 27550794, Free PMC Article
  5. Cloning and sequencing of the Saccharomyces cerevisiae gene LYP1 coding for a lysine-specific permease. Sychrova H, et al. Yeast, 1993 Jul. PMID 8368011

See all (47) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Extracellular loops matter - subcellular location and function of the lysine transporter Lyp1 from Saccharomyces cerevisiae.
    Title: Extracellular loops matter - subcellular location and function of the lysine transporter Lyp1 from Saccharomyces cerevisiae.
  2. Membrane Lipid Requirements of the Lysine Transporter Lyp1 from Saccharomyces cerevisiae.
    Title: Membrane Lipid Requirements of the Lysine Transporter Lyp1 from Saccharomyces cerevisiae.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables basic amino acid transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in amino acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in basic amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in basic amino acid transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in organic substance transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in eisosome IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 

General protein information

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Preferred Names
lysine permease
NP_014131.1
  • Lysine permease; one of three amino acid permeases (Alp1p, Can1p, Lyp1p) responsible for uptake of cationic amino acids

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    138550..140385
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183106.1 → NP_014131.1  TPA: lysine permease [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014131.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W0S6, P32487
    UniProtKB/TrEMBL
    A0A8H4F7J5, B3LPA7, C7GP95
    Conserved Domains (1) summary
    TIGR00913
    Location:107 → 583
    2A0310; amino acid permease (yeast)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P32487.2

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