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cysH phosphoadenosine phosphosulfate reductase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 885250, updated on 11-Dec-2020

Summary

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Gene symbol
cysH
Gene description
phosphoadenosine phosphosulfate reductase
Locus tag
Rv2392
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (2686367..2687131)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene oxygen-independent coproporphyrinogen III oxidase Neighboring gene hypothetical protein Neighboring gene resuscitation-promoting factor RpfD Neighboring gene sulfite reductase Neighboring gene ferrochelatase Neighboring gene gamma-glutamyltranspeptidase precursor GgtB Neighboring gene integral membrane protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. 5'-Adenosinephosphosulphate reductase (CysH) protects Mycobacterium tuberculosis against free radicals during chronic infection phase in mice. Senaratne RH, et al. Mol Microbiol, 2006 Mar. PMID 16553880
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. CysH is important for Mtb protection during the chronic infection phase, and that resistance to nitrosative and oxidative stress may be the mechanism of this protection. Thus
    Title: 5'-Adenosinephosphosulphate reductase (CysH) protects Mycobacterium tuberculosis against free radicals during chronic infection phase in mice.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
phosphoadenosine phosphosulfate reductase
NP_216908.1
  • PAPS reductase, thioredoxin DEP, (padops reductase) (3'-phosphoadenylylsulfate reductase) (PAPS sulfotransferase)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    2686367..2687131
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_216908.1 phosphoadenosine phosphosulfate reductase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_216908.1

    Status: PROVISIONAL

    Conserved Domains (1) summary
    TIGR02055
    Location:65 → 251
    APS_reductase; thioredoxin-dependent adenylylsulfate APS reductase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WIK3.1

Gene LinkOut

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