U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ubiA decaprenyl-phosphate phosphoribosyltransferase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 886129, updated on 6-Oct-2023

Summary

Go to the top of the page Help
Gene symbol
ubiA
Gene description
decaprenyl-phosphate phosphoribosyltransferase
Locus tag
Rv3806c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000962.3 (4268925..4269833, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene diacylglycerol acyltransferase/mycolyltransferase Ag85A Neighboring gene terminal beta-(1->2)-arabinofuranosyltransferase Neighboring gene decaprenylphosphoryl-5-phosphoribose phosphatase Neighboring gene galactofuranosyl transferase GlfT Neighboring gene UDP-galactopyranose mutase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Association of ubiA mutations and high-level of ethambutol resistance among Mycobacterium tuberculosis Thai clinical isolates. Tulyaprawat O, et al. Tuberculosis (Edinb), 2019 Jan. PMID 30711156
  2. ubiA (Rv3806c) encoding DPPR synthase involved in cell wall synthesis is associated with ethambutol resistance in Mycobacterium tuberculosis. He L, et al. Tuberculosis (Edinb), 2015 Mar. PMID 25547657
  3. Identification and active expression of the Mycobacterium tuberculosis gene encoding 5-phospho-{alpha}-d-ribose-1-diphosphate: decaprenyl-phosphate 5-phosphoribosyltransferase, the first enzyme committed to decaprenylphosphoryl-d-arabinose synthesis. Huang H, et al. J Biol Chem, 2005 Jul 1. PMID 15878857
  4. Polymorphisms in Rv3806c (ubiA) and the upstream region of embA in relation to ethambutol resistance in clinical isolates of Mycobacterium tuberculosis from North India. Giri A, et al. Tuberculosis (Edinb), 2018 Jan. PMID 29523326
  5. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Association of ubiA mutations and high-level of ethambutol resistance among Mycobacterium tuberculosis Thai clinical isolates.
    Title: Association of ubiA mutations and high-level of ethambutol resistance among Mycobacterium tuberculosis Thai clinical isolates.
  2. No polymorphisms associated with ethambutol resistance were identified in ubiA in clinical isolates of Mycobacterium tuberculosis.
    Title: Polymorphisms in Rv3806c (ubiA) and the upstream region of embA in relation to ethambutol resistance in clinical isolates of Mycobacterium tuberculosis from North India.
  3. ubiA (Rv3806c)encoding DPPR synthase is associated with ethambutol resistance in Mycobacterium tuberculosis.
    Title: ubiA (Rv3806c) encoding DPPR synthase involved in cell wall synthesis is associated with ethambutol resistance in Mycobacterium tuberculosis.
  4. Rv3806c is the first enzyme committed to decaprenylphosphoryl-d-arabinose synthesis
    Title: Identification and active expression of the Mycobacterium tuberculosis gene encoding 5-phospho-{alpha}-d-ribose-1-diphosphate: decaprenyl-phosphate 5-phosphoribosyltransferase, the first enzyme committed to decaprenylphosphoryl-d-arabinose synthesis.
Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

General protein information

Go to the top of the page Help
Preferred Names
decaprenyl-phosphate phosphoribosyltransferase
NP_218323.1
  • DPPR synthase (decaprenyl-phosphate 5-phosphoribosyltransferase)

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    4268925..4269833 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_218323.1 decaprenyl-phosphate phosphoribosyltransferase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_218323.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4MP94
    Conserved Domains (1) summary
    PRK12324
    Location:4 → 302
    PRK12324; decaprenyl-phosphate phosphoribosyltransferase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WFR5.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases