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fadD32 long-chain-fatty-acid--AMP ligase FadD32 [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 886130, updated on 4-Apr-2024

Summary

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Gene symbol
fadD32
Gene description
long-chain-fatty-acid--AMP ligase FadD32
Locus tag
Rv3801c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (4261153..4263066, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene insertion sequence element IS1557 transposase Neighboring gene propionyl-CoA carboxylase subunit beta AccD Neighboring gene polyketide synthase Neighboring gene membrane protein Neighboring gene MPT51/MPB51 antigen

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ser/Thr Phosphorylation Regulates the Fatty Acyl-AMP Ligase Activity of FadD32, an Essential Enzyme in Mycolic Acid Biosynthesis. Le NH, et al. J Biol Chem, 2016 Oct 21. PMID 27590338, Free PMC Article
  2. The dual function of the Mycobacterium tuberculosis FadD32 required for mycolic acid biosynthesis. Léger M, et al. Chem Biol, 2009 May 29. PMID 19477415
  3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

General protein information

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Preferred Names
long-chain-fatty-acid--AMP ligase FadD32
NP_218318.1
  • fatty-acid-AMP synthetase (fatty-acid-AMP synthase)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    4261153..4263066 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_218318.1 long-chain-fatty-acid--AMP ligase FadD32 [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_218318.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    A0A1R3Y582, Q7TTR2, X2BPL9
    UniProtKB/TrEMBL
    A0A0H3MJ88, A0A679LKA2, A0A7U4BYL9, A0A9P2M232, A0AA34UWF9
    Conserved Domains (1) summary
    PRK07769
    Location:8 → 637
    PRK07769; long-chain-fatty-acid--CoA ligase; Validated
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O53580.1

Gene LinkOut

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