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acpM meromycolate extension acyl carrier protein [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 888272, updated on 11-Dec-2020

Summary

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Gene symbol
acpM
Gene description
meromycolate extension acyl carrier protein
Locus tag
Rv2244
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (2517771..2518118)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene malonyl CoA-acyl carrier protein transacylase Neighboring gene ncRNA Neighboring gene 3-oxoacyl-ACP synthase 1 Neighboring gene 3-oxoacyl-ACP synthase 2 Neighboring gene acetyl-/propionyl-CoA carboxylase subunit beta

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Decrypting the oscillating nature of the 4'-phosphopantetheine arm in acyl carrier protein AcpM of Mycobacterium tuberculosis. Biswas R, et al. FEBS Lett, 2019 Mar. PMID 30847903
  2. Mycobacterium tuberculosis acyl carrier protein inhibits macrophage apoptotic death by modulating the reactive oxygen species/c-Jun N-terminal kinase pathway. Paik S, et al. Microbes Infect, 2019 Jan-Feb. PMID 29981934
  3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Decrypting the oscillating nature of the 4'-phosphopantetheine arm in acyl carrier protein AcpM of Mycobacterium tuberculosis has been reported.
    Title: Decrypting the oscillating nature of the 4'-phosphopantetheine arm in acyl carrier protein AcpM of Mycobacterium tuberculosis.
  2. Overexpressing mycobacterial acyl carrier protein (AcpM) in Mycobacterium smegmatis (M. smegmatis) enhances intracellular survival in primary bone marrow-derived macrophages (BMDMs). AcpM overexpression decreases reactive oxygen species (ROS) generation and activation of c-Jun N-terminal kinase (JNK) signaling. Treatment of BMDMs with recombinant AcpM inhibits the apoptosis and ROS/JNK signaling induced by M. smegmatis.
    Title: Mycobacterium tuberculosis acyl carrier protein inhibits macrophage apoptotic death by modulating the reactive oxygen species/c-Jun N-terminal kinase pathway.
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Pathways from PubChem

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General gene information

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Homology

General protein information

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Preferred Names
meromycolate extension acyl carrier protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    2517771..2518118
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_216760.1 meromycolate extension acyl carrier protein [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_216760.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P9WQF3
    UniProtKB/TrEMBL
    I6X3P5
    Conserved Domains (1) summary
    PRK00982
    Location:19 → 79
    acpP; acyl carrier protein; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WQF3.1

Gene LinkOut

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Molecular Biology Databases