U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

kstD 3-oxosteroid 1-dehydrogenase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 888422, updated on 4-Apr-2024

Summary

Go to the top of the page Help
Gene symbol
kstD
Gene description
3-oxosteroid 1-dehydrogenase
Locus tag
Rv3537
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000962.3 (3975369..3977060)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene 4-hydroxy-2-oxovalerate aldolase Neighboring gene acetaldehyde dehydrogenase Neighboring gene hydratase Neighboring gene dehydrogenase Neighboring gene PPE family protein PPE63

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The role of 3-ketosteroid 1(2)-dehydrogenase in the pathogenicity of Mycobacterium tuberculosis. Brzezinska M, et al. BMC Microbiol, 2013 Feb 20. PMID 23425360, Free PMC Article
  2. 3-Keto-5alpha-steroid Delta(1)-dehydrogenase from Rhodococcus erythropolis SQ1 and its orthologue in Mycobacterium tuberculosis H37Rv are highly specific enzymes that function in cholesterol catabolism. Knol J, et al. Biochem J, 2008 Mar 1. PMID 18031290
  3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The mutant kstD strain, which is unable to use cholesterol as a source of carbon and energy, has a limited ability to multiply in resting human macrophages following infection.
    Title: The role of 3-ketosteroid 1(2)-dehydrogenase in the pathogenicity of Mycobacterium tuberculosis.
  2. cloning and biochemical characterization
    Title: 3-Keto-5alpha-steroid Delta(1)-dehydrogenase from Rhodococcus erythropolis SQ1 and its orthologue in Mycobacterium tuberculosis H37Rv are highly specific enzymes that function in cholesterol catabolism.
Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

General protein information

Go to the top of the page Help
Preferred Names
3-oxosteroid 1-dehydrogenase

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    3975369..3977060
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_218054.1 3-oxosteroid 1-dehydrogenase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_218054.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q7D5C1
    UniProtKB/TrEMBL
    A0A0H3LG60, A0A7U4FCR2
    Conserved Domains (1) summary
    PRK07843
    Location:1 → 560
    PRK07843; 3-oxosteroid 1-dehydrogenase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P71864.3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases