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dapB 4-hydroxy-tetrahydrodipicolinate reductase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 888443, updated on 6-Oct-2023

Summary

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Gene symbol
dapB
Gene description
4-hydroxy-tetrahydrodipicolinate reductase
Locus tag
Rv2773c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (3081604..3082341, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene transmembrane protein Neighboring gene hypothetical protein Neighboring gene GCN5-like N-acetyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comparative structural and mechanistic studies of 4-hydroxy-tetrahydrodipicolinate reductases from Mycobacterium tuberculosis and Vibrio vulnificus. Pote S, et al. Biochim Biophys Acta Gen Subj, 2021 Jan. PMID 32980502, Free PMC Article
  2. Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of DapB (Rv2773c) from Mycobacterium tuberculosis. Kefala G, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2005 Jul 1. PMID 16511139, Free PMC Article
  3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Comparative structural and mechanistic studies of 4-hydroxy-tetrahydrodipicolinate reductases from Mycobacterium tuberculosis and Vibrio vulnificus.
    Title: Comparative structural and mechanistic studies of 4-hydroxy-tetrahydrodipicolinate reductases from Mycobacterium tuberculosis and Vibrio vulnificus.
  2. X-ray diffraction analysis of DapB (Rv2773c) from Mycobacterium tuberculosis
    Title: Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of DapB (Rv2773c) from Mycobacterium tuberculosis.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
4-hydroxy-tetrahydrodipicolinate reductase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    3081604..3082341 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_217289.1 4-hydroxy-tetrahydrodipicolinate reductase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_217289.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4M8W8
    Conserved Domains (1) summary
    PRK00048
    Location:1 → 244
    PRK00048; dihydrodipicolinate reductase; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WP23.1

Gene LinkOut

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Molecular Biology Databases
Research Materials