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acpS holo-ACP synthase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 888626, updated on 6-Oct-2023

Summary

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Gene symbol
acpS
Gene description
holo-ACP synthase
Locus tag
Rv2523c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (2839538..2839930, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene membrane protein Neighboring gene hypothetical protein Neighboring gene peroxiredoxin Neighboring gene fatty acid synthase Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mycobacterium tuberculosis acyl carrier protein synthase adopts two different pH-dependent structural conformations. Gokulan K, et al. Acta Crystallogr D Biol Crystallogr, 2011 Jul. PMID 21697604, Free PMC Article
  2. Structure-function analysis of the acyl carrier protein synthase (AcpS) from Mycobacterium tuberculosis. Dym O, et al. J Mol Biol, 2009 Nov 6. PMID 19733180
  3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. results show that apo-AcpS and AcpS-ADP adopt different conformations depending upon the pH conditions of the crystallization solution
    Title: Mycobacterium tuberculosis acyl carrier protein synthase adopts two different pH-dependent structural conformations.
  2. Results describe the crystal structure of the acyl carrier protein synthase (AcpS) from Mycobacterium tuberculosis (Mtb) at 1.95 A resolution.
    Title: Structure-function analysis of the acyl carrier protein synthase (AcpS) from Mycobacterium tuberculosis.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
holo-ACP synthase
NP_217039.1
  • holo-ACP synthase (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-ACPpantetheinephosphotransferase)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    2839538..2839930 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_217039.1 holo-ACP synthase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_217039.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4M4L3
    Conserved Domains (1) summary
    PRK00070
    Location:3 → 130
    acpS; 4'-phosphopantetheinyl transferase; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WQD3.1

Gene LinkOut

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Molecular Biology Databases
Research Materials