U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

gcd quinoprotein glucose dehydrogenase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 944830, updated on 23-Nov-2023

Summary

Go to the top of the page Help
Gene symbol
gcd
Gene description
quinoprotein glucose dehydrogenase
Primary source
ASAP:ABE-0000433
Locus tag
b0124
See related
ECOCYC:EG10369
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0123
Summary
Glucose dehydrogenase (Gcd) is a membrane-bound enzyme. [More information is available at EcoCyc: EG10369].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000913.3 (138835..141225, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative lipoprotein YacC Neighboring gene multicopper oxidase CueO Neighboring gene hypoxanthine phosphoribosyltransferase Neighboring gene carbonic anhydrase 2

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Function of a bound ubiquinone in Escherichia coli quinoprotein glucose dehydrogenase. Mustafa G, et al. Biofactors, 2008. PMID 19096097
  2. Menaquinone as well as ubiquinone as a bound quinone crucial for catalytic activity and intramolecular electron transfer in Escherichia coli membrane-bound glucose dehydrogenase. Mustafa G, et al. J Biol Chem, 2008 Oct 17. PMID 18708350, Free PMC Article
  3. Amino acid residues interacting with both the bound quinone and coenzyme, pyrroloquinoline quinone, in Escherichia coli membrane-bound glucose dehydrogenase. Mustafa G, et al. J Biol Chem, 2008 Aug 8. PMID 18550551
  4. Crystallization of quinoprotein glucose dehydrogenase variants and homologues by microseeding. Sanchez-Weatherby J, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2006 Jun 1. PMID 16754970, Free PMC Article
  5. Transient formation of a neutral ubisemiquinone radical and subsequent intramolecular electron transfer to pyrroloquinoline quinone in the Escherichia coli membrane-integrated glucose dehydrogenase. Kobayashi K, et al. Biochemistry, 2005 Oct 18. PMID 16216080

See all (38) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on complete protein
    Title: Topological analysis of quinoprotein glucose dehydrogenase in Escherichia coli and its ubiquinone-binding site.
Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables magnesium ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on CH-OH group of donors IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables pyrroloquinoline quinone binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables quinone binding IEA
Inferred from Electronic Annotation
more info
  
enables quinoprotein glucose dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables quinoprotein glucose dehydrogenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables quinoprotein glucose dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
enables ubiquinone binding IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in outer membrane-bounded periplasmic space IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
quinoprotein glucose dehydrogenase
NP_414666.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    138835..141225 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414666.1 quinoprotein glucose dehydrogenase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414666.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6N2YCZ6
    Conserved Domains (1) summary
    COG4993
    Location:11 → 793
    Gcd; Glucose dehydrogenase [Carbohydrate transport and metabolism]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.