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trpD anthranilate synthase subunit TrpD [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945109, updated on 6-Oct-2023

Summary

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Gene symbol
trpD
Gene description
anthranilate synthase subunit TrpD
Primary source
ASAP:ABE-0004241
Locus tag
b1263
See related
ECOCYC:EG11027
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1257; trpGD
Summary
Anthranilate phosphoribosyl transferase (TrpD) catalyzes the second step in the pathway of tryptophan biosynthesis. [More information is available at EcoCyc: EG11027].
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Genomic context

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Sequence:
NC_000913.3 (1319789..1321384, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene tryptophan synthase subunit alpha Neighboring gene tryptophan synthase subunit beta Neighboring gene fused indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase Neighboring gene anthranilate synthase subunit TrpE Neighboring gene trp operon leader peptide

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Initiation in vivo at the internal trp p2 promoter of Escherichia coli. Horowitz H, et al. J Biol Chem, 1983 Jul 10. PMID 6305961
  2. Nucleotide sequence of the trpD gene, encoding anthranilate synthetase component II of Escherichia coli. Horowitz H, et al. J Mol Biol, 1982 Apr 5. PMID 6283099
  3. Structural homology of the glutamine amidotransferase subunits of the anthranilate synthetases of Escherichia coli, Salmonella typhimurium and Serratia marcescens. Li SL, et al. Nature, 1974 Mar 1. PMID 4594441
  4. Localization of two functions of the phosphoribosyl anthranilate transferase of Escherichia coli to distinct regions of the polypeptide chain. Jackson EN, et al. J Bacteriol, 1974 Feb. PMID 4590474, Free PMC Article
  5. The anthranilate aggregate of Escherichia coli: kinetics of inhibition by tryptophan of phosphoribosyltransferase. Gonzalez JE, et al. Biochem Cell Biol, 1986 Jul. PMID 2428387

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on mature peptide
    Title: Structural homology of the glutamine amidotransferase subunits of the anthranilate synthetases of Escherichia coli, Salmonella typhimurium and Serratia marcescens.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General protein information

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Preferred Names
anthranilate synthase subunit TrpD
NP_415779.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1319789..1321384 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415779.1 anthranilate synthase subunit TrpD [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415779.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6N8QYT1
    Conserved Domains (1) summary
    PRK09522
    Location:1 → 531
    PRK09522; bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD
Nucleotide Protein
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