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ybiO moderate conductance mechanosensitive channel YbiO [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945935, updated on 2-May-2024

Summary

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Gene symbol
ybiO
Gene description
moderate conductance mechanosensitive channel YbiO
Primary source
ASAP:ABE-0002760
Locus tag
b0808
See related
ECOCYC:G6417
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0797
Summary
mscS, kefA, yjeP, ybiO, ybdG and ynaI are paralogs. [More information is available at EcoGene: EG13320]. YbiO exhibits sequence homology to the small mechanosensitive ion channel (MscS) however YbiO deletion mutants exhibit no detectable phenotype and its function remains unknown . [More information is available at EcoCyc: G6417].
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Genomic context

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Sequence:
NC_000913.3 (843255..845480, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene iron catecholate outer membrane transporter Fiu Neighboring gene DUF1471 domain-containing protein McbA Neighboring gene 23S rRNA m(6)A1618 methyltransferase Neighboring gene L-glutamine ABC transporter ATP binding subunit Neighboring gene L-glutamine ABC transporter membrane subunit Neighboring gene L-glutamine ABC transporter periplasmic binding protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The MscS-like channel YnaI has a gating mechanism based on flexible pore helices. Flegler VJ, et al. Proc Natl Acad Sci U S A, 2020 Nov 17. PMID 33148804, Free PMC Article
  2. Analysis of the kefA2 mutation suggests that KefA is a cation-specific channel involved in osmotic adaptation in Escherichia coli. McLaggan D, et al. Mol Microbiol, 2002 Jan. PMID 11985727
  3. Protection of Escherichia coli cells against extreme turgor by activation of MscS and MscL mechanosensitive channels: identification of genes required for MscS activity. Levina N, et al. EMBO J, 1999 Apr 1. PMID 10202137, Free PMC Article
  4. Identification of conserved, RpoS-dependent stationary-phase genes of Escherichia coli. Schellhorn HE, et al. J Bacteriol, 1998 Dec. PMID 9829938, Free PMC Article
  5. Characterization of three novel mechanosensitive channel activities in Escherichia coli. Edwards MD, et al. Channels (Austin), 2012 Jul-Aug. PMID 22874652, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The MscS-like channel YnaI has a gating mechanism based on flexible pore helices.
    Title: The MscS-like channel YnaI has a gating mechanism based on flexible pore helices.
  2. High level expression of YbiO proteins from a multicopy plasmid in the Delta7 strain (MJFGH) leads to substantial protection against hypoosmotic shock.
    Title: Characterization of three novel mechanosensitive channel activities in Escherichia coli.
Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables mechanosensitive monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 

General protein information

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Preferred Names
moderate conductance mechanosensitive channel YbiO

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    843255..845480 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415329.4 moderate conductance mechanosensitive channel YbiO [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415329.4

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8T6BMW9, A0AA87ESG5
    Conserved Domains (1) summary
    PRK11465
    Location:1 → 741
    PRK11465; putative mechanosensitive channel protein; Provisional
Nucleotide Protein
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