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ybdG miniconductance mechanosensitive channel YbdG [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946243, updated on 2-May-2024

Summary

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Gene symbol
ybdG
Gene description
miniconductance mechanosensitive channel YbdG
Primary source
ASAP:ABE-0001978
Locus tag
b0577
See related
ECOCYC:G6323
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0569
Summary
mscS, kefA, yjeP, ybiO, ybdG and ynaI are paralogs. [More information is available at EcoGene: EG12620]. Sequence analysis has identified YbdG as a member of the small mechanosensitive ion channel (MscS) family of proteins. [More information is available at EcoCyc: G6323].
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Genomic context

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Sequence:
NC_000913.3 (603416..604663, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene copper/silver export system RND permease Neighboring gene phenylalanine:H(+) symporter PheP Neighboring gene NAD(P)H-dependent nitroreductase NfsB Neighboring gene PF04237 family protein YbdF

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The mechanosensitive channel YbdG from Escherichia coli has a role in adaptation to osmotic up-shock. Amemiya S, et al. J Biol Chem, 2019 Aug 16. PMID 31256002, Free PMC Article
  2. Multiple mechanosensitive ion channels from Escherichia coli, activated at different thresholds of applied pressure. Berrier C, et al. J Membr Biol, 1996 May. PMID 8661505
  3. Physical characterisation of the Escherichia coli B gene encoding nitroreductase and its over-expression in Escherichia coli K12. Michael NP, et al. FEMS Microbiol Lett, 1994 Dec 1. PMID 7813889
  4. YbdG in Escherichia coli is a threshold-setting mechanosensitive channel with MscM activity. Schumann U, et al. Proc Natl Acad Sci U S A, 2010 Jul 13. PMID 20616037, Free PMC Article
  5. Comparison of SDS- and methanol-assisted protein solubilization and digestion methods for Escherichia coli membrane proteome analysis by 2-D LC-MS/MS. Zhang N, et al. Proteomics, 2007 Feb. PMID 17309111

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables mechanosensitive monoatomic ion channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mechanosensitive monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
  
enables mechanosensitive monoatomic ion channel activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to osmotic stress IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cellular response to osmotic stress IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cellular response to osmotic stress IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to osmotic stress IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
miniconductance mechanosensitive channel YbdG

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    603416..604663 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415109.1 miniconductance mechanosensitive channel YbdG [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415109.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8T6QCL8
    Conserved Domains (1) summary
    pfam00924
    Location:144 → 396
    MS_channel; Mechanosensitive ion channel
Nucleotide Protein
Heading Accession and Version

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