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znuC Zn(2(+)) ABC transporter ATP binding subunit [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946374, updated on 4-Apr-2024

Summary

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Gene symbol
znuC
Gene description
Zn(2(+)) ABC transporter ATP binding subunit
Primary source
ASAP:ABE-0006198
Locus tag
b1858
See related
ECOCYC:G7018
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1859; yebM
Summary
[More information is available at EcoCyc: G7018].
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Genomic context

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Sequence:
NC_000913.3 (1942662..1943417)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene peptidoglycan endopeptidase MepM Neighboring gene Zn(2(+)) ABC transporter periplasmic binding protein Neighboring gene Zn(2(+)) ABC transporter membrane subunit Neighboring gene Holliday junction branch migration complex subunit RuvB Neighboring gene Holliday junction branch migration complex subunit RuvA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcriptional response of Escherichia coli to external zinc. Yamamoto K, et al. J Bacteriol, 2005 Sep. PMID 16159766, Free PMC Article
  2. SoxS increases the expression of the zinc uptake system ZnuACB in an Escherichia coli murine pyelonephritis model. Warner DM, et al. J Bacteriol, 2012 Mar. PMID 22210763, Free PMC Article
  3. The zinc-responsive regulator Zur and its control of the znu gene cluster encoding the ZnuABC zinc uptake system in Escherichia coli. Patzer SI, et al. J Biol Chem, 2000 Aug 11. PMID 10816566
  4. Members of the Fur protein family regulate iron and zinc transport in E. coli and characteristics of the Fur-regulated fhuF protein. Hantke K. J Mol Microbiol Biotechnol, 2002 May. PMID 11931550
  5. ZupT is a Zn(II) uptake system in Escherichia coli. Grass G, et al. J Bacteriol, 2002 Feb. PMID 11790762, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. This work implicates SoxS control of znuCB expression as a key factor in persistence of Escherichia coli in murine pyelonephritis.
    Title: SoxS increases the expression of the zinc uptake system ZnuACB in an Escherichia coli murine pyelonephritis model.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ABC-type zinc transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding ISM
Inferred from Sequence Model
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in response to zinc ion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in zinc ion import across plasma membrane NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in zinc ion transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ATP-binding cassette (ABC) transporter complex RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Zn(2(+)) ABC transporter ATP binding subunit
NP_416372.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1942662..1943417
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416372.1 Zn(2(+)) ABC transporter ATP binding subunit [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416372.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7EFV5, A0AA87JVP2
    Conserved Domains (1) summary
    PRK09544
    Location:1 → 251
    znuC; high-affinity zinc transporter ATPase; Reviewed
Nucleotide Protein
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