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cysZ sulfate:H(+) symporter [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946875, updated on 11-Apr-2024

Summary

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Gene symbol
cysZ
Gene description
sulfate:H(+) symporter
Primary source
ASAP:ABE-0007953
Locus tag
b2413
See related
ECOCYC:EG10003
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2408
Summary
A cysZ mutant is deficient in sulfate assimilation . [More information is available at EcoCyc: EG10003].
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Genomic context

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Sequence:
NC_000913.3 (2531463..2532224)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA ligase Neighboring gene cell division protein ZipA Neighboring gene cysteine synthase A Neighboring gene phosphocarrier protein HPr

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Escherichia coli CysZ is a pH dependent sulfate transporter that can be inhibited by sulfite. Zhang L, et al. Biochim Biophys Acta, 2014 Jul. PMID 24657232
  2. Phylogeny of metabolic pathways: O-acetylserine sulphydrylase A is homologous to the tryptophan synthase beta subunit. Levy S, et al. Mol Microbiol, 1988 Nov. PMID 3062311
  3. Direct binding of FtsZ to ZipA, an essential component of the septal ring structure that mediates cell division in E. coli. Hale CA, et al. Cell, 1997 Jan 24. PMID 9008158
  4. DNA sequences of the cysK regions of Salmonella typhimurium and Escherichia coli and linkage of the cysK regions to ptsH. Byrne CR, et al. J Bacteriol, 1988 Jul. PMID 3290198, Free PMC Article
  5. Two separate genes involved in sulphate transport in Escherichia coli K12. Parra F, et al. J Gen Microbiol, 1983 Feb. PMID 6341507

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables high-affinity sulfate:proton symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables high-affinity sulfate:proton symporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables sulfate transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables sulfate transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in amino acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in cysteine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within cysteine biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in cysteine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in sulfate assimilation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sulfate assimilation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within sulfate assimilation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within sulfate transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in sulfate transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in sulfate transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
sulfate:H(+) symporter

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2531463..2532224
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416908.1 sulfate:H(+) symporter [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416908.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0AA88ETR5
    Conserved Domains (1) summary
    PRK04949
    Location:3 → 253
    PRK04949; putative sulfate transport protein CysZ; Validated
Nucleotide Protein
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