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hyfA hydrogenase 4 component A [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946959, updated on 4-Apr-2024

Summary

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Gene symbol
hyfA
Gene description
hydrogenase 4 component A
Primary source
ASAP:ABE-0008179
Locus tag
b2481
See related
ECOCYC:EG11150
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2477; yffE
Summary
This subunit contains four 4Fe-4S clusters and may be involved in electron transfer. [More information is available at EcoCyc: EG11150].
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Genomic context

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Sequence:
NC_000913.3 (2601201..2601818)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene 4-hydroxy-tetrahydrodipicolinate synthase Neighboring gene putative transcriptional regulator GcvR Neighboring gene thiol peroxidase Neighboring gene hydrogenase 4 component B Neighboring gene hydrogenase 4 component C

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A molecular analysis of the 53.3 minute region of the Escherichia coli linkage map. Andrews SC, et al. J Gen Microbiol, 1991 Feb. PMID 2016588
  2. Participation of hyf-encoded hydrogenase 4 in molecular hydrogen release coupled with proton-potassium exchange in Escherichia coli. Bagramyan K, et al. Membr Cell Biol, 2001. PMID 11817571
  3. Phosphorylation of ribosomal proteins in HeLa cells infected with vaccinia virus. Kaerlein M, et al. Nature, 1976 Jan 15. PMID 1246353
  4. Expression and regulation of a silent operon, hyf, coding for hydrogenase 4 isoenzyme in Escherichia coli. Self WT, et al. J Bacteriol, 2004 Jan. PMID 14702328, Free PMC Article
  5. Quantitative whole-genome analysis of DNA-protein interactions by in vivo methylase protection in E. coli. Tavazoie S, et al. Nat Biotechnol, 1998 Jun. PMID 9624689

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of [Ni-Fe] hydrogenase complex RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 

General protein information

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Preferred Names
hydrogenase 4 component A

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2601201..2601818
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416976.4 hydrogenase 4 component A [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416976.4

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A7L7EHY9
    Conserved Domains (1) summary
    cd10554
    Location:4 → 170
    HycB_like; HycB, HydN and similar proteins
Nucleotide Protein
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