guaA GMP synthetase [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Gene symbol: guaA
Gene description: GMP synthetase
Primary source: ASAP:ABE-0008254
Locus tag: b2507
See related: ECOCYC:EG10420
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK2503
Summary: GMP synthetase catalyzes the glutamine- or ammonia-dependent synthesis of GMP from XMP . [More information is available at EcoCyc: EG10420].
NEW: Try the new Gene table
Try the new Transcript table

NC_000913.3 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

N-terminus verified by Edman degradation on complete protein
Title: Nucleotide sequence of the guaA gene encoding GMP synthetase of Escherichia coli K12.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables GMP synthase (glutamine-hydrolyzing) activity	IDA Inferred from Direct Assay more info	PubMed
enables GMP synthase (glutamine-hydrolyzing) activity	IEA Inferred from Electronic Annotation more info
enables GMP synthase activity	IBA Inferred from Biological aspect of Ancestor more info
enables GMP synthase activity	IDA Inferred from Direct Assay more info	PubMed
enables GMP synthase activity	IEA Inferred from Electronic Annotation more info
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables ligase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in GMP biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in GMP biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within GMP biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in GMP metabolic process	IEA Inferred from Electronic Annotation more info
involved_in glutamine metabolic process	IEA Inferred from Electronic Annotation more info
involved_in purine nucleotide biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytosol	HDA more info	PubMed
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed