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uidB glucuronide:H(+) symporter [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947484, updated on 2-May-2024

Summary

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Gene symbol
uidB
Gene description
glucuronide:H(+) symporter
Primary source
ASAP:ABE-0005407
Locus tag
b1616
See related
ECOCYC:EG11658
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1611; gusB; uidP
Summary
Transport activity is enhanced by putative porin UidC. [More information is available at EcoGene: EG11658]. UidB, also known as GusB, is a proton-dependent transporter specific for - and -glucuronides . [More information is available at EcoCyc: EG11658].
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Genomic context

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Sequence:
NC_000913.3 (1692890..1694263, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF945 domain-containing protein YdgA Neighboring gene outer membrane porin family protein UidC Neighboring gene beta-glucuronidase Neighboring gene DNA-binding transcriptional repressor UidR Neighboring gene 7-alpha-hydroxysteroid dehydrogenase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Investigation on stability of transporter protein, glucuronide transporter from Escherichia coli. Ishii N. J Membr Biol, 2010 Jun. PMID 20490474
  2. The gusBC genes of Escherichia coli encode a glucuronide transport system. Liang WJ, et al. J Bacteriol, 2005 Apr. PMID 15774881, Free PMC Article
  3. beta-Glucuronidase from Escherichia coli as a gene-fusion marker. Jefferson RA, et al. Proc Natl Acad Sci U S A, 1986 Nov. PMID 3534890, Free PMC Article
  4. Active membrane transport and receptor proteins from bacteria. Saidijam M, et al. Biochem Soc Trans, 2005 Aug. PMID 16042616
  5. Microbial drug efflux proteins of the major facilitator superfamily. Saidijam M, et al. Curr Drug Targets, 2006 Jul. PMID 16842212

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. It is likely that GusB resides in the membrane as a pentamer.
    Title: Investigation on stability of transporter protein, glucuronide transporter from Escherichia coli.
  2. Isolation, function, and mapping of the gene in a naturally-occuring E. coli strain.
    Title: The gusBC genes of Escherichia coli encode a glucuronide transport system.
Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables symporter activity IEA
Inferred from Electronic Annotation
more info
  
enables transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in carbohydrate transport IEA
Inferred from Electronic Annotation
more info
  
involved_in organic substance transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sodium ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
glucuronide:H(+) symporter

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1692890..1694263 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416133.1 glucuronide:H(+) symporter [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416133.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5B9A7P2, A0A7A2XWR7
    Conserved Domains (1) summary
    PRK09848
    Location:1 → 448
    PRK09848; glucuronide transporter; Provisional
Nucleotide Protein
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