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kdsD D-arabinose 5-phosphate isomerase KdsD [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947734, updated on 4-Apr-2024

Summary

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Gene symbol
kdsD
Gene description
D-arabinose 5-phosphate isomerase KdsD
Primary source
ASAP:ABE-0010504
Locus tag
b3197
See related
ECOCYC:G7662
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3186; yrbH
Summary
KdsD is homologous to GutQ and KpsF. [More information is available at EcoGene: EG12803]. D-arabinose-5-phosphate is a precursor for KDO (2-keto-3-deoxy-octonate), a constituent in the cell wall lipopolysaccharide. [More information is available at EcoCyc: G7662].
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Genomic context

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Sequence:
NC_000913.3 (3341266..3342252)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene intermembrane phospholipid transport system, ATP binding subunit MlaF Neighboring gene putative transport protein YrbG Neighboring gene 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC Neighboring gene lipopolysaccharide transport system protein LptC Neighboring gene lipopolysaccharide transport system protein LptA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structure prediction and functional analysis of KdsD, an enzyme involved in lipopolysaccharide biosynthesis. Sommaruga S, et al. Biochem Biophys Res Commun, 2009 Oct 16. PMID 19664604
  2. Escherichia coli YrbH is a D-arabinose 5-phosphate isomerase. Meredith TC, et al. J Biol Chem, 2003 Aug 29. PMID 12805358
  3. D-phosphoarabinoisomerase and D-ribulokinase in Escherichia coli. Lim R, et al. J Biol Chem, 1966 Oct 10. PMID 5332197
  4. Identification of GutQ from Escherichia coli as a D-arabinose 5-phosphate isomerase. Meredith TC, et al. J Bacteriol, 2005 Oct. PMID 16199563, Free PMC Article
  5. Escherichia coli YrbI is 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase. Wu J, et al. J Biol Chem, 2003 May 16. PMID 12639950

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The structure of the KdsD SIS domain has been predicted by homology modeling using the hypothetical 3etn protein as a template.
    Title: Structure prediction and functional analysis of KdsD, an enzyme involved in lipopolysaccharide biosynthesis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables arabinose-5-phosphate isomerase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables arabinose-5-phosphate isomerase activity IEA
Inferred from Electronic Annotation
more info
  
enables carbohydrate derivative binding IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carbohydrate derivative metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within keto-3-deoxy-D-manno-octulosonic acid biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in lipopolysaccharide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein homotetramerization IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
D-arabinose 5-phosphate isomerase KdsD
NP_417664.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3341266..3342252
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417664.1 D-arabinose 5-phosphate isomerase KdsD [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417664.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376JTI0, A0A403CYH1
    Conserved Domains (1) summary
    PRK10892
    Location:3 → 328
    PRK10892; arabinose-5-phosphate isomerase KdsD
Nucleotide Protein
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