U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

nudE ADP-sugar diphosphatase NudE [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947906, updated on 4-Feb-2024

Summary

Go to the top of the page Help
Gene symbol
nudE
Gene description
ADP-sugar diphosphatase NudE
Primary source
ASAP:ABE-0011086
Locus tag
b3397
See related
ECOCYC:G7740
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3384; yrfE
Summary
Nudix hydrolase. [More information is available at EcoGene: EG12926]. NudE belongs to the family of Nudix hydrolases . [More information is available at EcoCyc: G7740].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000913.3 (3525589..3526149, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA utilization protein HofN Neighboring gene DNA utilization protein HofM Neighboring gene peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA Neighboring gene inner membrane protein IgaA Neighboring gene purine nucleotidase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Orf186 represents a new member of the Nudix hydrolases, active on adenosine(5')triphospho(5')adenosine, ADP-ribose, and NADH. O'Handley SF, et al. J Biol Chem, 1998 Feb 6. PMID 9452430
  2. Reconstruction of Escherichia coli mrcA (PBP 1a) mutants lacking multiple combinations of penicillin binding proteins. Meberg BM, et al. J Bacteriol, 2001 Oct. PMID 11567017, Free PMC Article
  3. Structural analysis of a set of proteins resulting from a bacterial genomics project. Badger J, et al. Proteins, 2005 Sep 1. PMID 16021622
  4. The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymes. Bessman MJ, et al. J Biol Chem, 1996 Oct 11. PMID 8810257
  5. Localization, annotation, and comparison of the Escherichia coli K-12 proteome under two states of growth. Lopez-Campistrous A, et al. Mol Cell Proteomics, 2005 Aug. PMID 15911532

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ADP-ribose diphosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables ADP-sugar diphosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ADP-sugar diphosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables magnesium ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in nucleoside phosphate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribose phosphate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
ADP-sugar diphosphatase NudE
NP_417856.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3525589..3526149 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417856.1 ADP-sugar diphosphatase NudE [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417856.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5B9AGM2
    Conserved Domains (1) summary
    PRK11762
    Location:1 → 184
    nudE; adenosine nucleotide hydrolase NudE; Provisional
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.