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adeP adenine:H(+) symporter [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948224, updated on 23-Nov-2023

Summary

Gene symbol
adeP
Gene description
adenine:H(+) symporter
Primary source
ASAP:ABE-0012148
Locus tag
b3714
See related
ECOCYC:EG11724
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3707; purP; yieG
Summary
Paralogs YicO and PurP are 74% identical and YicO may be a second adenine permease. [More information is available at EcoGene: EG11724]. PurP functions in energized high-affinity adenine uptake in Escherichia coli. [More information is available at EcoCyc: EG11724].
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Genomic context

Sequence:
NC_000913.3 (3895272..3896609, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative phosphopantetheinyl transferase Neighboring gene quinone reductase Neighboring gene 6-phosphogluconate phosphatase Neighboring gene putative inner membrane protein

Pathways from PubChem

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables adenine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables adenine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
enables adenine transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables nucleobase transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables solute:proton symporter activity IDA
Inferred from Direct Assay
more info
PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within adenine transport IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within adenine transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in purine nucleobase transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane RCA
inferred from Reviewed Computational Analysis
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3895272..3896609 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418170.1 adenine:H(+) symporter [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418170.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8T3UCD5
    Conserved Domains (1) summary
    COG2252
    Location:10441
    AzgA; Xanthine/uracil/vitamin C permease, AzgA family [Nucleotide transport and metabolism]