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srlD sorbitol-6-phosphate 2-dehydrogenase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948937, updated on 23-Nov-2023

Summary

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Gene symbol
srlD
Gene description
sorbitol-6-phosphate 2-dehydrogenase
Primary source
ASAP:ABE-0008896
Locus tag
b2705
See related
ECOCYC:EG10971
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2700; gutD
Summary
False positive lipoprotein prediction, unprocessed, verified amino terminus. [More information is available at EcoGene: EG10971].
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Genomic context

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Sequence:
NC_000913.3 (2827737..2828516)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene sorbitol-specific PTS enzyme IIC2 component Neighboring gene sorbitol-specific PTS enzyme IIBC1 component Neighboring gene sorbitol-specific PTS enzyme IIA component Neighboring gene DNA-binding transcriptional activator GutM Neighboring gene DNA-binding transcriptional repressor SrlR Neighboring gene D-arabinose 5-phosphate isomerase GutQ

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Preliminary studies on the inhibition of D-sorbitol-6-phosphate 2-dehydrogenase from Escherichia coli with substrate analogues. Roux C, et al. J Enzyme Inhib Med Chem, 2006 Apr. PMID 16791965
  2. Mutations affecting transport of the hexitols D-mannitol, D-glucitol, and galactitol in Escherichia coli K-12: isolation and mapping. Lengeler J. J Bacteriol, 1975 Oct. PMID 1100602, Free PMC Article
  3. Purification and properties of D-mannitol-1-phosphate dehydrogenase and D-glucitol-6-phosphate dehydrogenase from Escherichia coli. Novotny MJ, et al. J Bacteriol, 1984 Sep. PMID 6384188, Free PMC Article
  4. Physical mapping of the srl recA region of Escherichia coli: analysis of Tn10 generated insertions and deletions. Willis DK, et al. Mol Gen Genet, 1981. PMID 6278241
  5. Genetic analysis of the Escherichia coli K-12 srl region. McEntee K. J Bacteriol, 1977 Dec. PMID 336611, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on complete protein
    Title: Purification and properties of D-mannitol-1-phosphate dehydrogenase and D-glucitol-6-phosphate dehydrogenase from Escherichia coli.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sorbitol-6-phosphate 2-dehydrogenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables sorbitol-6-phosphate 2-dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein homotetramerization IPI
Inferred from Physical Interaction
more info
 PubMed 
involved_in sorbitol catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of protein-containing complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
sorbitol-6-phosphate 2-dehydrogenase
NP_417185.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2827737..2828516
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417185.1 sorbitol-6-phosphate 2-dehydrogenase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417185.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    B1A9T9
    Conserved Domains (1) summary
    PRK12384
    Location:1 → 259
    PRK12384; sorbitol-6-phosphate dehydrogenase; Provisional
Nucleotide Protein
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