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Central Nervous System Solitary Fibrous Tumor, Grade 2

MedGen UID:
1376264
•Concept ID:
C4329639
•
Neoplastic Process
Synonyms: Central Nervous System Solitary Fibrous Tumor/Hemangiopericytoma, Grade 2; CNS Solitary Fibrous Tumor, Grade 2; CNS Solitary Fibrous Tumor/Hemangiopericytoma, Grade 2

Definition

A solitary fibrous tumor that arises from the central nervous system. It corresponds to the more cellular, less collagenous tumor with plump cells and staghorn vasculature which was diagnosed as central nervous system hemangiopericytoma in the past. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCentral Nervous System Solitary Fibrous Tumor, Grade 2

Professional guidelines

PubMed

Intracranial solitary fibrous tumor/hemangiopericytoma: tumor reclassification and assessment of treatment outcome via the 2016 WHO classification.
Shin DW, Kim JH, Chong S, Song SW, Kim YH, Cho YH, Hong SH, Nam SJ
J Neurooncol 2021 Sep;154(2):171-178. Epub 2021 Aug 20 doi: 10.1007/s11060-021-03733-7. PMID: 34417710
Diagnosis and treatment of solitary fibrous tumor/hemangiopericytoma of central nervous system. Retrospective report of 17 patients and literature review.
Ma L, Wang L, Fang X, Zhao CH, Sun L
Neuro Endocrinol Lett 2018 May;39(2):88-94. PMID: 30183202
Immunohistochemical Approach to the Differential Diagnosis of Meningiomas and Their Mimics.
Boulagnon-Rombi C, Fleury C, Fichel C, Lefour S, Marchal Bressenot A, Gauchotte G
J Neuropathol Exp Neurol 2017 Apr 1;76(4):289-298. doi: 10.1093/jnen/nlx008. PMID: 28340171

Recent clinical studies

Etiology

Hemangioblastomas and Other Vascular Origating Tumors of Brain or Spinal Cord.
Vetrano IG, Gioppo A, Faragò G, Pinzi V, Pollo B, Broggi M, Schiariti M, Ferroli P, Acerbi F
Adv Exp Med Biol 2023;1405:377-403. doi: 10.1007/978-3-031-23705-8_14. PMID: 37452946
Intracranial solitary fibrous tumor/hemangiopericytoma: tumor reclassification and assessment of treatment outcome via the 2016 WHO classification.
Shin DW, Kim JH, Chong S, Song SW, Kim YH, Cho YH, Hong SH, Nam SJ
J Neurooncol 2021 Sep;154(2):171-178. Epub 2021 Aug 20 doi: 10.1007/s11060-021-03733-7. PMID: 34417710
Aggressive Behavior Predictors in Solitary Fibrous Tumor: Demographic, Clinical, and Histopathologic Characteristics of 81 Cases.
Hassani M, Jung S, Garzia L, Ghodsi E, Alcindor T, Turcotte RE
Ann Surg Oncol 2021 Oct;28(11):6861-6867. Epub 2021 Jan 29 doi: 10.1245/s10434-021-09592-w. PMID: 33512676
Hemangiopericytoma/Solitary Fibrous Tumor in the central nervous system. Experience with surgery and radiotherapy as a complementary treatment: A 10-year analysis of a heterogeneous series in a single tertiary center.
González-Vargas PM, Thenier-Villa JL, Sanromán Álvarez P, Serantes Combo A, Calero Félix L, Galárraga Campoverde RA, Azevedo González E, Martín-Gallego Á, Martínez-Rolan R, de la Lama Zaragoza A, Conde Alonso C
Neurocirugia (Astur : Engl Ed) 2020 Jan-Feb;31(1):14-23. Epub 2019 Jul 24 doi: 10.1016/j.neucir.2019.06.001. PMID: 31351895
Diagnosis and treatment of solitary fibrous tumor/hemangiopericytoma of central nervous system. Retrospective report of 17 patients and literature review.
Ma L, Wang L, Fang X, Zhao CH, Sun L
Neuro Endocrinol Lett 2018 May;39(2):88-94. PMID: 30183202

Diagnosis

Hemangioblastomas and Other Vascular Origating Tumors of Brain or Spinal Cord.
Vetrano IG, Gioppo A, Faragò G, Pinzi V, Pollo B, Broggi M, Schiariti M, Ferroli P, Acerbi F
Adv Exp Med Biol 2023;1405:377-403. doi: 10.1007/978-3-031-23705-8_14. PMID: 37452946
Meningioma and Other Meningeal Tumors.
Bailo M, Gagliardi F, Boari N, Spina A, Piloni M, Castellano A, Mortini P
Adv Exp Med Biol 2023;1405:73-97. doi: 10.1007/978-3-031-23705-8_3. PMID: 37452935
Molecular Advances in Central Nervous System Mesenchymal Tumors.
Helgager J, Driver J, Hoffman S, Bi WL
Surg Pathol Clin 2020 Jun;13(2):291-303. doi: 10.1016/j.path.2020.02.002. PMID: 32389268
Meningeal solitary fibrous tumor/hemangiopericytoma: Emphasizing on STAT 6 immunohistochemistry with a review of literature.
Ahmad Z, Tariq MU, Din NU
Neurol India 2018 Sep-Oct;66(5):1419-1426. doi: 10.4103/0028-3886.241365. PMID: 30233017
Diagnosis and treatment of solitary fibrous tumor/hemangiopericytoma of central nervous system. Retrospective report of 17 patients and literature review.
Ma L, Wang L, Fang X, Zhao CH, Sun L
Neuro Endocrinol Lett 2018 May;39(2):88-94. PMID: 30183202

Prognosis

Meningioma and Other Meningeal Tumors.
Bailo M, Gagliardi F, Boari N, Spina A, Piloni M, Castellano A, Mortini P
Adv Exp Med Biol 2023;1405:73-97. doi: 10.1007/978-3-031-23705-8_3. PMID: 37452935
Aggressive Behavior Predictors in Solitary Fibrous Tumor: Demographic, Clinical, and Histopathologic Characteristics of 81 Cases.
Hassani M, Jung S, Garzia L, Ghodsi E, Alcindor T, Turcotte RE
Ann Surg Oncol 2021 Oct;28(11):6861-6867. Epub 2021 Jan 29 doi: 10.1245/s10434-021-09592-w. PMID: 33512676
Molecular Advances in Central Nervous System Mesenchymal Tumors.
Helgager J, Driver J, Hoffman S, Bi WL
Surg Pathol Clin 2020 Jun;13(2):291-303. doi: 10.1016/j.path.2020.02.002. PMID: 32389268
Hemangiopericytoma/Solitary Fibrous Tumor in the central nervous system. Experience with surgery and radiotherapy as a complementary treatment: A 10-year analysis of a heterogeneous series in a single tertiary center.
González-Vargas PM, Thenier-Villa JL, Sanromán Álvarez P, Serantes Combo A, Calero Félix L, Galárraga Campoverde RA, Azevedo González E, Martín-Gallego Á, Martínez-Rolan R, de la Lama Zaragoza A, Conde Alonso C
Neurocirugia (Astur : Engl Ed) 2020 Jan-Feb;31(1):14-23. Epub 2019 Jul 24 doi: 10.1016/j.neucir.2019.06.001. PMID: 31351895
Meningeal solitary fibrous tumor/hemangiopericytoma: Emphasizing on STAT 6 immunohistochemistry with a review of literature.
Ahmad Z, Tariq MU, Din NU
Neurol India 2018 Sep-Oct;66(5):1419-1426. doi: 10.4103/0028-3886.241365. PMID: 30233017

Clinical prediction guides

Hemangioblastomas and Other Vascular Origating Tumors of Brain or Spinal Cord.
Vetrano IG, Gioppo A, Faragò G, Pinzi V, Pollo B, Broggi M, Schiariti M, Ferroli P, Acerbi F
Adv Exp Med Biol 2023;1405:377-403. doi: 10.1007/978-3-031-23705-8_14. PMID: 37452946
Rare hypervascular pancreatic tumors diagnosed as asynchronous metastases of central nervous system solitary fibrous tumor/hemangiopericytoma.
Mizukoshi K, Yamauchi Y, Kitaura M, Fukuda A, Seno H
Clin J Gastroenterol 2022 Feb;15(1):221-227. Epub 2021 Oct 15 doi: 10.1007/s12328-021-01533-0. PMID: 34652718
Solitary fibrous tumor of thoracic cavity, extra-thoracic sites and central nervous system: Clinicopathologic features and association with local recurrence and metastasis.
Alexiev BA, Finkelman BS, Streich L, Bautista MM, Pollack SM, Jennings LJ, Brat DJ
Pathol Res Pract 2021 Aug;224:153531. Epub 2021 Jun 18 doi: 10.1016/j.prp.2021.153531. PMID: 34171600
Aggressive Behavior Predictors in Solitary Fibrous Tumor: Demographic, Clinical, and Histopathologic Characteristics of 81 Cases.
Hassani M, Jung S, Garzia L, Ghodsi E, Alcindor T, Turcotte RE
Ann Surg Oncol 2021 Oct;28(11):6861-6867. Epub 2021 Jan 29 doi: 10.1245/s10434-021-09592-w. PMID: 33512676
Meningeal solitary fibrous tumor/hemangiopericytoma: Emphasizing on STAT 6 immunohistochemistry with a review of literature.
Ahmad Z, Tariq MU, Din NU
Neurol India 2018 Sep-Oct;66(5):1419-1426. doi: 10.4103/0028-3886.241365. PMID: 30233017

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