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Disorder of the central nervous system

MedGen UID:: 3306
•Concept ID:: C0007682
•: Disease or Syndrome

Synonyms:	Central Nervous System Disease; Central Nervous System Diseases; Central Nervous System Disorder; Central Nervous System Disorders; CNS Disease; CNS Diseases
SNOMED CT:	Disorder of the central nervous system (23853001); Central nervous system (CNS) disease (23853001); Encephalomyeloneuropathy (23853001)

Definition

A non-neoplastic or neoplastic disorder which affects the brain and/or spinal cord. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVDisorder of the central nervous system

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Disorder by Site
      - Disorder of nervous system
        Disorder of the central nervous system
        Brain disorder
        Acute Febrile Encephalopathy
        Brain Death
        Central auditory dysfunction
        Auditory processing disorder
        Central hearing loss
        Chronic brain syndrome
        Cerebral palsy
        Persistent vegetative state
        Diaschisis
        Disorder of basal ganglia
        Basal ganglia cerebrovascular disorder
        Blepharospasm-oromandibular dystonia syndrome
        Chorea gravidarum
        Huntington disease
        Multiple system atrophy
        Neuroleptic malignant syndrome
        Parkinsonian disorder
        Pigmentary pallidal degeneration
        Progressive supranuclear palsy
        Torsion dystonia
        Tourette syndrome
        Wilson disease
        Encephalopathy with sepsis
        Hypoxia of brain
        Brain hypoxia - ischemia
        Intracranial swelling
        Non-Neoplastic Brain Disorder
        Brain Development Abnormality
        Cerebellar degeneration
        Cerebellar hypoplasia
        Cerebral abscess
        Cerebritis
        Cerebrovascular disorder
        Corticobasal degeneration disorder
        Encephalitis
        Encephalomalacia
        Encephalopathy
        Epilepsy
        Hamartoma of brain
        Hemimegalencephaly
        Hydrocephalus
        Olivopontocerebellar atrophy
        Schizencephaly
        Thalamic disorder
        Organic mental disorder
        Nonpsychotic Mental Disorder Following Organic Brain Damage
        Transient organic mental disorder
        High pressure neurological syndrome
        Hyperekplexia
        Developmental and epileptic encephalopathy, 8
        Hereditary hyperekplexia
        Hyperekplexia 1
        Hyperekplexia 2
        Hyperekplexia 3
        Hyperekplexia 4
        Sporadic hyperekplexia
        Infectious disease of central nervous system
        Arachnoiditis
        Bacterial infection of central nervous system
        Bacterial meningitis
        Central nervous system tuberculosis
        Lyme neuroborreliosis
        Neurosyphilis
        Brain abscess
        Encephalomyelitis
        Encephalomyelitis, Equine
        Infection causing encephalomyelitis
        Epidural abscess
        Fungal infection of central nervous system
        Fungal meningitis
        Neuroaspergillosis
        HTLV-1-associated myelopathy-tropical spastic paraparesis
        Infectious encephalitis
        Bacterial encephalitis
        Infectious meningitis
        Infectious Meningoencephalitis
        Leukoencephalopathy
        Diffuse leukoencephalopathy
        Diffuse spongiform leukoencephalopathy
        Hereditary Central Nervous System Demyelinating Diseases
        Human immunodeficiency virus leukoencephalopathy
        Posterior leukoencephalopathy
        Posterior reversible encephalopathy syndrome
        Progressive leukoencephalopathy
        Meningoencephalitis
        Myelitis
        Parasitic infection of central nervous system
        Central Nervous System Helminthiasis
        Central Nervous System Protozoal Infections
        Perimeningeal Infections
        Subdural empyema
        Poliomyelitis
        Vaccine-Associated Paralytic Poliomyelitis
        Prion disease
        Bovine Spongiform Encephalopathy
        Wasting Disease, Chronic
        Viral infection of central nervous system
        Cerebral Ventriculitis
        Movement disorder
        Abnormal head movements
        Jerky head movements
        Abnormal posturing
        Abnormal reflex
        Abnormal postural reflex
        Abnormal superficial reflex
        Hyperreflexia
        Primitive reflex
        Reduced tendon reflexes
        Astasia
        Asterixis
        Diminished movement
        Akinesia
        Hypokinesia
        Dyskinesia
        Catalepsy
        Extrapyramidal dyskinesia
        Habit tic
        Orofacial dyskinesia
        Tardive dyskinesia
        Dystonia
        Dystonia 12
        Dystonia 16
        Episodic kinesigenic dyskinesia 1
        Familial Dystonia
        Dystonic disorder
        Axial dystonia
        Focal dystonia
        Generalized dystonia
        Hemidystonia
        Limb dystonia
        Oculogyric crisis
        Paroxysmal dystonia
        Frontal release signs
        Gait disturbance
        Antalgic gait
        Broad-based gait
        Cautious gait
        Cerebellar ataxia associated with quadrupedal gait
        Crouch gait
        Difficulty walking backward
        Dystonic gait
        Falls
        Freezing of gait
        Gait ataxia
        Gait imbalance
        Impaired heel-walking ability
        Impaired tandem gait
        Impaired toe-walking ability
        Inability to walk
        Neurogenic claudication
        Shuffling gait
        Spastic gait
        Steppage gait
        Tip-toe gait
        Unsteady gait
        Waddling gait
        Hyperkinetic movements
        Involuntary movements
        Chvostek sign
        Fasciculations
        Self-mutilation of tongue and lips due to involuntary movements
        Shakes
        Muscle fibrillation
        Facial-lingual fasciculations
        Myokymia
        Eyelid myokymia
        Facial myokymia
        Postural instability
        Stooped posture
        Synkinesis
        Bimanual synkinesia
        Facial synkinesis
        Tic
        Tourettism
        Myelopathy
        Cervical myelopathy
        Abnormal cervical myelogram
        Infarction of spinal cord
        Spinal Cord Infarct During Birth
        Myelocystocele
        Pneumorrhachis
        Spinal Cord Hamartoma
        Spinal Cord Vascular Diseases
        Spinal cord ischemia
        Subacute combined degeneration of spinal cord
        Neoplasm of the central nervous system
        Adult Central Nervous System Neoplasm
        Adult astrocytic tumor
        Adult central nervous system germ cell tumor
        Adult central nervous system primitive neuroectodermal neoplasm
        Adult embryonal tumor with multilayered rosettes, c19mc-altered
        Adult Ependymal Tumor
        Adult Ganglioglioma
        Adult Intracranial Neoplasm
        Adult Meningioma
        Adult Oligodendroglial Tumor
        Adult Spinal Cord Neoplasm
        Benign neoplasm of the central nervous system
        Cerebral hamartoma
        Choroid plexus papilloma
        Hemangioblastoma
        Meningioma
        Multiple central nervous system lipomas
        Neuroepithelial cyst
        Childhood Central Nervous System Neoplasm
        Childhood astrocytic tumor
        Childhood Benign Central Nervous System Neoplasm
        Childhood central nervous system germ cell tumor
        Childhood Ependymal Tumor
        Childhood ganglioglioma
        Childhood Intracranial Neoplasm
        Childhood Malignant Central Nervous System Neoplasm
        Childhood Mixed Glioma
        Childhood oligodendroglioma
        Childhood spinal cord tumor
        Pediatric meningioma
        Recurrent Childhood Central Nervous System Neoplasm
        Intracranial Neoplasm
        Benign Intracranial Neoplasm
        Intracranial meningioma
        Malignant Intracranial Neoplasm
        Metastatic Intracranial Malignant Neoplasm
        Neoplasm of brain
        Posterior Fossa Neoplasm
        Recurrent Intracranial Neoplasm
        Skull base neoplasm
        Visual Pathway Neoplasm
        Intraspinal Neoplasm
        Cauda equina neoplasm
        Epidural spinal canal neoplasm
        Intradural extramedullary spinal canal neoplasm
        Intraspinal meningioma
        Spinal cord tumor
        Malignant neoplasm of the central nervous system
        Central Nervous System Carcinoma
        Central Nervous System Embryonal Tumor
        Central Nervous System Histiocytic Sarcoma
        Central Nervous System Melanoma
        Cerebral germinoma
        Choroid plexus carcinoma
        Glioma
        Malignant Central Nervous System Germ Cell Tumor
        Medulloblastoma
        Metastatic Malignant Neoplasm in the Central Nervous System
        Neuroblastic tumor
        Recurrent Primary Malignant Central Nervous System Neoplasm
        Refractory Primary Malignant Central Nervous System Neoplasm
        Neuronal/glioneuronal neoplasm of the central nervous system
        Anaplastic ganglioglioma
        Cerebellar Glioneuronal and Neuronal Tumors
        Desmoplastic infantile astrocytoma/ganglioglioma
        Dysembryoplastic neuroepithelial tumor
        Dysembryoplastic Neuroepithelial-Like Tumor of the Septum Pellucidum
        Gangliocytoma
        Ganglioglioma
        Ganglioneuroma
        Lhermitte-Duclos disease
        Papillary glioneuronal tumor
        Rosette-forming glioneuronal tumor
        Primary Central Nervous System Neoplasm
        Benign neoplasm of meninges
        Benign neoplasm of spinal cord
        Central nervous system germ cell tumor
        Central Nervous System Hemangioblastoma
        Central nervous system melanocytic neoplasm
        Central nervous system mesenchymal non-meningothelial tumor
        Central Nervous System Paraganglioma
        Central Nervous System SMARCB1/INI1-Deficient Tumor
        Metastatic Primary Malignant Central Nervous System Neoplasm
        Neoplasm of the posterior pituitary
        Primary brain neoplasm
        Primary central nervous system lymphoma
        Recurrent Primary Central Nervous System Neoplasm
        Refractory Primary Central Nervous System Neoplasm
        Sellar Chordoma
        Sellar Neuroblastoma
        Non-Neoplastic Central Nervous System Disorder
        Alice in Wonderland syndrome
        Central Nervous System Hamartoma
        Degenerative disease of the central nervous system
        Amyotrophic lateral sclerosis
        Brachial amyotrophic diplegia
        Dementia
        Demyelinating disease of central nervous system
        Dentatorubral-pallidoluysian atrophy
        Extrapyramidal disease
        Frontotemporal dementia and/or amyotrophic lateral sclerosis 1
        Hereditary Neurodegenerative Disorder
        Hereditary spastic paraplegia
        Pelizaeus-Merzbacher disease
        Pick disease
        Spinocerebellar atrophy
        Striatonigral degeneration
        Infantile neuroaxonal dystrophy
        Meningitis
        Chronic lymphocytic meningitis
        Multiple sclerosis
        Neurodevelopmental disorder
        Attention Deficit and Disruptive Behavior Disorders
        Child Behavior Disorders
        Child Development Disorders, Pervasive
        Congenital meningocele
        Fetal Neurodevelopmental Disorder
        Motor skill disorder
        Neuronitis
        Polyradiculopathy
        Secondary Parkinson disease
        Sensory disorder
        Disorder of taste
        Tactile Disorder
        Spina bifida
        Cervical spina bifida
        Spina bifida occulta
        Syringomyelia
        Primary syringomyelia
        Secondary syringomyelia
        Syringomyelia and Hydromyelia
        Vascular malformation of the nervous system
        Arteriovenous Malformation, Intracranial
        Central Nervous System Cavernous Hemangioma
        Central Nervous System Venous Angioma
        Meningioangiomatosis
        Sinus pericranii
        Vein of Galen malformation
        Ocular motility disease
        Pneumocephalus

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Acuted disseminated encephalomyelitis.

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Disorder of the central nervous system

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

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