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Muscle cancer

MedGen UID:
151927
•Concept ID:
C0684743
•
Neoplastic Process
Synonyms: Cancer of Muscle; Cancer of the Muscle; Cancer, Muscle; Cancers, Muscle; Muscle Cancer; Muscle Cancers
SNOMED CT: Cancer of muscle (363495004); CA - Cancer of muscle (363495004); Malignant tumor of muscle (363495004)
 
Monarch Initiative: MONDO:0005864

Definition

A malignant neoplasm affecting the skeletal or smooth muscles. Malignant neoplasms arising from the skeletal muscles are called rhabdomyosarcomas. Malignant neoplasms arising from the smooth muscles are called leiomyosarcomas. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMuscle cancer

Professional guidelines

PubMed

Treatment of Non-Metastatic Muscle-Invasive Bladder Cancer: AUA/ASCO/SUO Guideline (2017; Amended 2020, 2024).
Holzbeierlein J, Bixler BR, Buckley DI, Chang SS, Holmes RS, James AC, Kirkby E, McKiernan JM, Schuckman A
J Urol 2024 Jul;212(1):3-10. Epub 2024 Apr 25 doi: 10.1097/JU.0000000000003981. PMID: 38661067
Potential of Creatine in Glucose Management and Diabetes.
Solis MY, Artioli GG, Gualano B
Nutrients 2021 Feb 9;13(2) doi: 10.3390/nu13020570. PMID: 33572228Free PMC Article
European Association of Urology Guidelines on Muscle-invasive and Metastatic Bladder Cancer: Summary of the 2020 Guidelines.
Witjes JA, Bruins HM, Cathomas R, Compérat EM, Cowan NC, Gakis G, Hernández V, Linares Espinós E, Lorch A, Neuzillet Y, Rouanne M, Thalmann GN, Veskimäe E, Ribal MJ, van der Heijden AG
Eur Urol 2021 Jan;79(1):82-104. Epub 2020 Apr 29 doi: 10.1016/j.eururo.2020.03.055. PMID: 32360052

Recent clinical studies

Etiology

Nephroblastoma overexpressed (NOV/CCN3) gene: a paired-domain-specific PAX3-FKHR transcription target that promotes survival and motility in alveolar rhabdomyosarcoma cells.
Zhang Y, Wang C
Oncogene 2011 Aug 11;30(32):3549-62. Epub 2011 Mar 21 doi: 10.1038/onc.2011.69. PMID: 21423212Free PMC Article

Diagnosis

Validity of the GLIM criteria for the diagnosis of malnutrition in patients with colorectal cancer: A multicenter study on the diagnostic performance of different indicators of reduced muscle mass and disease severity.
Dos Santos ALS, Santos BC, Frazão LN, Miranda AL, Fayh APT, Silva FM, Gonzalez MC, Correia MITD, Souza NC, Anastácio LR, Maurício SF
Nutrition 2024 Mar;119:112324. Epub 2023 Dec 6 doi: 10.1016/j.nut.2023.112324. PMID: 38215671
Leiomyosarcoma, a rare smooth muscle cancer in the pancreas: An adjuvant radiotherapy treatment approach.
Taghizadeh Kermani A, Khooei A, Aliakbarian M, Arastouei S
Cancer Rep (Hoboken) 2023 Jun;6(6):e1820. Epub 2023 Apr 24 doi: 10.1002/cnr2.1820. PMID: 37095058Free PMC Article

Therapy

Electroactive functional microenvironments from bioactive polymers: A new strategy to address cancer.
Ribeiro S, Soares M, Hermenegildo B, Correia V, Díez AG, Lanceros-Mendez S, Ribeiro C
Biomater Adv 2022 Jun;137:212849. Epub 2022 May 14 doi: 10.1016/j.bioadv.2022.212849. PMID: 35929277
Histone methyltransferase KMT1A restrains entry of alveolar rhabdomyosarcoma cells into a myogenic differentiated state.
Lee MH, Jothi M, Gudkov AV, Mal AK
Cancer Res 2011 Jun 1;71(11):3921-31. Epub 2011 Apr 14 doi: 10.1158/0008-5472.CAN-10-3358. PMID: 21493592Free PMC Article
PDGFR-A is a therapeutic target in alveolar rhabdomyosarcoma.
Taniguchi E, Nishijo K, McCleish AT, Michalek JE, Grayson MH, Infante AJ, Abboud HE, Legallo RD, Qualman SJ, Rubin BP, Keller C
Oncogene 2008 Nov 20;27(51):6550-60. Epub 2008 Aug 4 doi: 10.1038/onc.2008.255. PMID: 18679424Free PMC Article

Prognosis

Validity of the GLIM criteria for the diagnosis of malnutrition in patients with colorectal cancer: A multicenter study on the diagnostic performance of different indicators of reduced muscle mass and disease severity.
Dos Santos ALS, Santos BC, Frazão LN, Miranda AL, Fayh APT, Silva FM, Gonzalez MC, Correia MITD, Souza NC, Anastácio LR, Maurício SF
Nutrition 2024 Mar;119:112324. Epub 2023 Dec 6 doi: 10.1016/j.nut.2023.112324. PMID: 38215671

Clinical prediction guides

Validity of the GLIM criteria for the diagnosis of malnutrition in patients with colorectal cancer: A multicenter study on the diagnostic performance of different indicators of reduced muscle mass and disease severity.
Dos Santos ALS, Santos BC, Frazão LN, Miranda AL, Fayh APT, Silva FM, Gonzalez MC, Correia MITD, Souza NC, Anastácio LR, Maurício SF
Nutrition 2024 Mar;119:112324. Epub 2023 Dec 6 doi: 10.1016/j.nut.2023.112324. PMID: 38215671
Credentialing a preclinical mouse model of alveolar rhabdomyosarcoma.
Nishijo K, Chen QR, Zhang L, McCleish AT, Rodriguez A, Cho MJ, Prajapati SI, Gelfond JA, Chisholm GB, Michalek JE, Aronow BJ, Barr FG, Randall RL, Ladanyi M, Qualman SJ, Rubin BP, LeGallo RD, Wang C, Khan J, Keller C
Cancer Res 2009 Apr 1;69(7):2902-11. doi: 10.1158/0008-5472.CAN-08-3723. PMID: 19339268Free PMC Article

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