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Malignant neoplastic disease

MedGen UID:
14297
•Concept ID:
C0006826
•
Neoplastic Process
Synonym: Cancer
SNOMED CT: Malignant neoplastic disease (363346000); Cancer (363346000); CA - Cancer (363346000); Malignant neoplasm (363346000); Malignant tumor (363346000); Malignant neoplasm morphology (1240414004); Malignancy (1240414004); Malignant tumor (1240414004); Blastoma (1240414004); Malignant neoplasm (1240414004); Cancer (1240414004); Unclassified malignant tumor (1240414004)
 
Monarch Initiative: MONDO:0004992

Definition

A neoplasm composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas, Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Malignant neoplastic disease

Professional guidelines

PubMed

Curcumin as an adjuvant to breast cancer treatment.
Kumar P, Kadakol A, Shasthrula PK, Mundhe NA, Jamdade VS, Barua CC, Gaikwad AB
Anticancer Agents Med Chem 2015;15(5):647-56. doi: 10.2174/1871520615666150101125918. PMID: 25553436
Intrathecal chemotherapy for treatment of leptomeningeal dissemination of metastatic tumours.
Beauchesne P
Lancet Oncol 2010 Sep;11(9):871-9. Epub 2010 Jul 2 doi: 10.1016/S1470-2045(10)70034-6. PMID: 20598636

Curated

UK NICE Guideline NG12, Suspected cancer: recognition and referral, 2023

Suggested Reading

PubMed

Cancer Genetics Risk Assessment and Counseling (PDQ®): Health Professional Version.
PDQ Cancer Genetics Editorial Board
2002 PMID: 26389258
Cancer Genetics Overview (PDQ®): Health Professional Version.
PDQ Cancer Genetics Editorial Board
2002 PMID: 26389204

Recent clinical studies

Etiology

The impact of industrialization on malignant neoplastic disease of bone in England: A study of medieval and industrial samples.
Soria S, Buckberry J
Int J Paleopathol 2022 Sep;38:32-40. Epub 2022 Jun 23 doi: 10.1016/j.ijpp.2022.05.007. PMID: 35753114
Application of minimal residual disease monitoring in pediatric patients with acute lymphoblastic leukemia.
Qin X, Zhang MY, Liu WJ
Eur Rev Med Pharmacol Sci 2018 Oct;22(20):6885-6895. doi: 10.26355/eurrev_201810_16158. PMID: 30402854
Neoplastic disease after acute coronary syndrome: incidence, duration, and features: the ABC-4* Study on Heart Disease.
Berton G, Cordiano R, Cavuto F, Bagato F, Segafredo B, Pasquinucci M
J Cardiovasc Med (Hagerstown) 2018 Oct;19(10):546-553. doi: 10.2459/JCM.0000000000000701. PMID: 30119096
Influence of Obesity on the Course of Malignant Neoplastic Disease in Patients After Pulmonary Metastasectomy.
Rzechonek A, Błasiak P, Pniewski G, Cierpikowski P, Mościbrodzka M, Ornat M, Grzegrzółka J, Brzecka A
In Vivo 2018 Jan-Feb;32(1):197-202. doi: 10.21873/invivo.11225. PMID: 29275320Free PMC Article
New prognostic biomarkers in multiple myeloma.
Szudy-Szczyrek A, Szczyrek M, Soroka-Wojtaszko M, Hus M
Postepy Hig Med Dosw (Online) 2016 Jan 4;70(0):811-9. doi: 10.5604/17322693.1211183. PMID: 27463592

Diagnosis

The impact of industrialization on malignant neoplastic disease of bone in England: A study of medieval and industrial samples.
Soria S, Buckberry J
Int J Paleopathol 2022 Sep;38:32-40. Epub 2022 Jun 23 doi: 10.1016/j.ijpp.2022.05.007. PMID: 35753114
Application of minimal residual disease monitoring in pediatric patients with acute lymphoblastic leukemia.
Qin X, Zhang MY, Liu WJ
Eur Rev Med Pharmacol Sci 2018 Oct;22(20):6885-6895. doi: 10.26355/eurrev_201810_16158. PMID: 30402854
Neoplastic disease after acute coronary syndrome: incidence, duration, and features: the ABC-4* Study on Heart Disease.
Berton G, Cordiano R, Cavuto F, Bagato F, Segafredo B, Pasquinucci M
J Cardiovasc Med (Hagerstown) 2018 Oct;19(10):546-553. doi: 10.2459/JCM.0000000000000701. PMID: 30119096
New prognostic biomarkers in multiple myeloma.
Szudy-Szczyrek A, Szczyrek M, Soroka-Wojtaszko M, Hus M
Postepy Hig Med Dosw (Online) 2016 Jan 4;70(0):811-9. doi: 10.5604/17322693.1211183. PMID: 27463592
Pulmonary disease caused by Candida species.
Masur H, Rosen PP, Armstrong D
Am J Med 1977 Dec;63(6):914-25. doi: 10.1016/0002-9343(77)90546-0. PMID: 343588

Therapy

The role of liver surgery in simultaneous synchronous colorectal liver metastases and colorectal cancer resections: a literature review of 1730 patients underwent open and minimally invasive surgery.
Avella P, Vaschetti R, Cappuccio M, Gambale F, DE Meis L, Rafanelli F, Brunese MC, Guerra G, Scacchi A, Rocca A
Minerva Surg 2022 Dec;77(6):582-590. doi: 10.23736/S2724-5691.22.09716-7. PMID: 36409039
Descriptive Analysis of Everolimus Conversion in Liver Transplant Recipients With Malignant Neoplastic Disease.
Nogueras López F, Espinosa Aguilar MD, Abellán Alfocea P, Ortega Suazo EJ, González Sánchez M, Redondo Cerezo E, López Garrido MA
Transplant Proc 2020 Mar;52(2):553-555. Epub 2020 Feb 5 doi: 10.1016/j.transproceed.2019.12.011. PMID: 32035682
Sicca Syndrome Associated with Immune Checkpoint Inhibitor Therapy.
Warner BM, Baer AN, Lipson EJ, Allen C, Hinrichs C, Rajan A, Pelayo E, Beach M, Gulley JL, Madan RA, Feliciano J, Grisius M, Long L, Powers A, Kleiner DE, Cappelli L, Alevizos I
Oncologist 2019 Sep;24(9):1259-1269. Epub 2019 Apr 17 doi: 10.1634/theoncologist.2018-0823. PMID: 30996010Free PMC Article
New prognostic biomarkers in multiple myeloma.
Szudy-Szczyrek A, Szczyrek M, Soroka-Wojtaszko M, Hus M
Postepy Hig Med Dosw (Online) 2016 Jan 4;70(0):811-9. doi: 10.5604/17322693.1211183. PMID: 27463592
Curcumin as an adjuvant to breast cancer treatment.
Kumar P, Kadakol A, Shasthrula PK, Mundhe NA, Jamdade VS, Barua CC, Gaikwad AB
Anticancer Agents Med Chem 2015;15(5):647-56. doi: 10.2174/1871520615666150101125918. PMID: 25553436

Prognosis

The impact of industrialization on malignant neoplastic disease of bone in England: A study of medieval and industrial samples.
Soria S, Buckberry J
Int J Paleopathol 2022 Sep;38:32-40. Epub 2022 Jun 23 doi: 10.1016/j.ijpp.2022.05.007. PMID: 35753114
Evolving therapeutic strategies for advanced hepatocellular carcinoma.
Qureshi A, Michel M, Lerner J, Dasanu CA
Expert Opin Pharmacother 2021 Dec;22(18):2495-2506. Epub 2021 Jul 15 doi: 10.1080/14656566.2021.1953473. PMID: 34252328
Application of minimal residual disease monitoring in pediatric patients with acute lymphoblastic leukemia.
Qin X, Zhang MY, Liu WJ
Eur Rev Med Pharmacol Sci 2018 Oct;22(20):6885-6895. doi: 10.26355/eurrev_201810_16158. PMID: 30402854
Neoplastic disease after acute coronary syndrome: incidence, duration, and features: the ABC-4* Study on Heart Disease.
Berton G, Cordiano R, Cavuto F, Bagato F, Segafredo B, Pasquinucci M
J Cardiovasc Med (Hagerstown) 2018 Oct;19(10):546-553. doi: 10.2459/JCM.0000000000000701. PMID: 30119096
New prognostic biomarkers in multiple myeloma.
Szudy-Szczyrek A, Szczyrek M, Soroka-Wojtaszko M, Hus M
Postepy Hig Med Dosw (Online) 2016 Jan 4;70(0):811-9. doi: 10.5604/17322693.1211183. PMID: 27463592

Clinical prediction guides

The impact of industrialization on malignant neoplastic disease of bone in England: A study of medieval and industrial samples.
Soria S, Buckberry J
Int J Paleopathol 2022 Sep;38:32-40. Epub 2022 Jun 23 doi: 10.1016/j.ijpp.2022.05.007. PMID: 35753114
Evolving therapeutic strategies for advanced hepatocellular carcinoma.
Qureshi A, Michel M, Lerner J, Dasanu CA
Expert Opin Pharmacother 2021 Dec;22(18):2495-2506. Epub 2021 Jul 15 doi: 10.1080/14656566.2021.1953473. PMID: 34252328
Descriptive Analysis of Everolimus Conversion in Liver Transplant Recipients With Malignant Neoplastic Disease.
Nogueras López F, Espinosa Aguilar MD, Abellán Alfocea P, Ortega Suazo EJ, González Sánchez M, Redondo Cerezo E, López Garrido MA
Transplant Proc 2020 Mar;52(2):553-555. Epub 2020 Feb 5 doi: 10.1016/j.transproceed.2019.12.011. PMID: 32035682
Application of minimal residual disease monitoring in pediatric patients with acute lymphoblastic leukemia.
Qin X, Zhang MY, Liu WJ
Eur Rev Med Pharmacol Sci 2018 Oct;22(20):6885-6895. doi: 10.26355/eurrev_201810_16158. PMID: 30402854
Neoplastic disease after acute coronary syndrome: incidence, duration, and features: the ABC-4* Study on Heart Disease.
Berton G, Cordiano R, Cavuto F, Bagato F, Segafredo B, Pasquinucci M
J Cardiovasc Med (Hagerstown) 2018 Oct;19(10):546-553. doi: 10.2459/JCM.0000000000000701. PMID: 30119096

Recent systematic reviews

The risk between thyrotropin suppression and bone mineral density in differentiated thyroid cancer.
Zou Y, Li B, Wang X, Mao J, Zhang Y
Medicine (Baltimore) 2022 Dec 2;101(48):e31991. doi: 10.1097/MD.0000000000031991. PMID: 36482589Free PMC Article
Taking stock: A systematic review of archaeological evidence of cancers in human and early hominin remains.
Hunt KJ, Roberts C, Kirkpatrick C
Int J Paleopathol 2018 Jun;21:12-26. doi: 10.1016/j.ijpp.2018.03.002. PMID: 29773338

Supplemental Content

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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2023
      UK NICE Guideline NG12, Suspected cancer: recognition and referral, 2023

    Consumer resources

    Reviews

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