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Abnormal tricuspid valve leaflet morphology

MedGen UID:
1624499
•Concept ID:
C4531115
•
Anatomical Abnormality
HPO: HP:0031443

Definition

Any structural anomaly of the leaflets (also known as cusps) of the tricuspid valve. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal tricuspid valve leaflet morphology

Professional guidelines

PubMed

Echocardiography and monitoring patients receiving dopamine agonist therapy for hyperprolactinaemia: A joint position statement of the British Society of Echocardiography, the British Heart Valve Society and the Society for Endocrinology.
Steeds R, Stiles C, Sharma V, Chambers J, Lloyd G, Drake W
Clin Endocrinol (Oxf) 2019 May;90(5):662-669. Epub 2019 Feb 28 doi: 10.1111/cen.13940. PMID: 30818417
Echocardiographic criteria to detect unicuspid aortic valve morphology.
Ewen S, Karliova I, Weber P, Schirmer SH, Abdul-Khaliq H, Schöpe J, Mahfoud F, Schäfers HJ
Eur Heart J Cardiovasc Imaging 2019 Jan 1;20(1):40-44. doi: 10.1093/ehjci/jex344. PMID: 29346529

Recent clinical studies

Etiology

Ebstein's Anomaly: From Fetus to Adult-Literature Review and Pathway for Patient Care.
Ramcharan TKW, Goff DA, Greenleaf CE, Shebani SO, Salazar JD, Corno AF
Pediatr Cardiol 2022 Oct;43(7):1409-1428. Epub 2022 Apr 23 doi: 10.1007/s00246-022-02908-x. PMID: 35460366
Single-Leaflet Aortic Valve Reconstruction Utilizing the Ozaki Technique in Patients With Congenital Aortic Valve Disease.
Marathe SP, Chávez M, Sleeper LA, Marx GR, Friedman K, Feins EN, Del Nido PJ, Baird CW
Semin Thorac Cardiovasc Surg 2022 Winter;34(4):1262-1272. Epub 2021 Oct 29 doi: 10.1053/j.semtcvs.2021.10.009. PMID: 34757016
Transcatheter aortic valve replacement in bicuspid aortic valve stenosis.
Yoon SH, Webb JG, Leon MB, Makkar R
Prog Cardiovasc Dis 2020 Jul-Aug;63(4):482-487. Epub 2020 Jun 25 doi: 10.1016/j.pcad.2020.06.007. PMID: 32592707
Transcatheter aortic valve implantation in bicuspid anatomy.
Zhao ZG, Jilaihawi H, Feng Y, Chen M
Nat Rev Cardiol 2015 Feb;12(2):123-8. Epub 2014 Oct 14 doi: 10.1038/nrcardio.2014.161. PMID: 25311233
Evaluation of tricuspid valve morphology and function by transthoracic three-dimensional echocardiography.
Muraru D, Badano LP, Sarais C, Soldà E, Iliceto S
Curr Cardiol Rep 2011 Jun;13(3):242-9. doi: 10.1007/s11886-011-0176-3. PMID: 21365261

Diagnosis

Ebstein's Anomaly: From Fetus to Adult-Literature Review and Pathway for Patient Care.
Ramcharan TKW, Goff DA, Greenleaf CE, Shebani SO, Salazar JD, Corno AF
Pediatr Cardiol 2022 Oct;43(7):1409-1428. Epub 2022 Apr 23 doi: 10.1007/s00246-022-02908-x. PMID: 35460366
Unicuspid Aortic Valve: A Rare Congenital Anomaly.
Pan J
Cardiology 2022;147(2):207-215. Epub 2021 Dec 29 doi: 10.1159/000521623. PMID: 34965530
Tricuspid Valve Dysplasia at Fetal Autopsy.
Shanmugam S, Sennaiyan UN, Krishna MR
Fetal Pediatr Pathol 2022 Jun;41(3):529-532. Epub 2020 Oct 16 doi: 10.1080/15513815.2020.1831665. PMID: 33063582
The Congenital Tricuspid Valve Spectrum: From Ebstein to Dysplasia.
Stephens EH, Dearani JA, Qureshi MY, Ammash N, Maleszewski JJ
World J Pediatr Congenit Heart Surg 2020 Nov;11(6):783-791. doi: 10.1177/2150135120949235. PMID: 33164686
Ebstein Anomaly in the Adult Patient.
Fuchs MM, Connolly HM
Cardiol Clin 2020 Aug;38(3):353-363. Epub 2020 Jun 6 doi: 10.1016/j.ccl.2020.04.004. PMID: 32622490

Therapy

Transcatheter aortic valve replacement in bicuspid aortic valve stenosis.
Yoon SH, Webb JG, Leon MB, Makkar R
Prog Cardiovasc Dis 2020 Jul-Aug;63(4):482-487. Epub 2020 Jun 25 doi: 10.1016/j.pcad.2020.06.007. PMID: 32592707
Heart valve scaffold fabrication: Bioinspired control of macro-scale morphology, mechanics and micro-structure.
D'Amore A, Luketich SK, Raffa GM, Olia S, Menallo G, Mazzola A, D'Accardi F, Grunberg T, Gu X, Pilato M, Kameneva MV, Badhwar V, Wagner WR
Biomaterials 2018 Jan;150:25-37. Epub 2017 Oct 6 doi: 10.1016/j.biomaterials.2017.10.011. PMID: 29031049Free PMC Article
Transcatheter aortic valve implantation in bicuspid anatomy.
Zhao ZG, Jilaihawi H, Feng Y, Chen M
Nat Rev Cardiol 2015 Feb;12(2):123-8. Epub 2014 Oct 14 doi: 10.1038/nrcardio.2014.161. PMID: 25311233
When lithium hurts: a look at Ebstein anomaly.
Osiro S, Tiwari KJ, Mathenge N, Rodriguez JR, Tubbs RS, Loukas M
Cardiol Rev 2013 Sep-Oct;21(5):257-63. doi: 10.1097/CRD.0b013e318280c966. PMID: 23269033
Bicuspid aortic valve and associated aortopathy: surgical considerations.
Bruckner BA, Reardon MJ
Methodist Debakey Cardiovasc J 2010 Jan-Mar;6(1):29-32. doi: 10.14797/mdcj-6-1-29. PMID: 20360656

Prognosis

Clinical outcomes of bicuspid versus tricuspid aortic valve stenosis after transcatheter aortic valve replacement with self-expandable valves.
Jin Q, Chen S, Yang X, Li M, Li W, Zhang X, Zhou D, Lam YY, Ge J
BMC Cardiovasc Disord 2022 Dec 12;22(1):540. doi: 10.1186/s12872-022-02943-9. PMID: 36503424Free PMC Article
Ebstein Anomaly in the Adult Patient.
Fuchs MM, Connolly HM
Cardiol Clin 2020 Aug;38(3):353-363. Epub 2020 Jun 6 doi: 10.1016/j.ccl.2020.04.004. PMID: 32622490
Coexistent bicuspid aortic valve and mitral valve prolapse: epidemiology, phenotypic spectrum, and clinical implications.
Padang R, Enriquez-Sarano M, Pislaru SV, Maalouf JF, Nkomo VT, Mankad SV, Maltais S, Suri RM, Schaff HV, Michelena HI
Eur Heart J Cardiovasc Imaging 2019 Jun 1;20(6):677-686. doi: 10.1093/ehjci/jey166. PMID: 30445616
Epidemiology, anatomy, pathophysiology and clinical evaluation of functional tricuspid regurgitation.
Sun YP, O'Gara PT
Minerva Cardioangiol 2017 Oct;65(5):469-479. Epub 2017 Apr 10 doi: 10.23736/S0026-4725.17.04398-5. PMID: 28398019
When lithium hurts: a look at Ebstein anomaly.
Osiro S, Tiwari KJ, Mathenge N, Rodriguez JR, Tubbs RS, Loukas M
Cardiol Rev 2013 Sep-Oct;21(5):257-63. doi: 10.1097/CRD.0b013e318280c966. PMID: 23269033

Clinical prediction guides

Tricuspid valve repair with papillary muscle approximation for congenital tricuspid valve regurgitation due to tricuspid valve dysplasia.
Maeda T, Ikeda T, Yoshizawa K
Cardiol Young 2023 Apr;33(4):660-662. Epub 2022 Aug 1 doi: 10.1017/S1047951122002499. PMID: 35912591
Clinical outcomes of bicuspid versus tricuspid aortic valve stenosis after transcatheter aortic valve replacement with self-expandable valves.
Jin Q, Chen S, Yang X, Li M, Li W, Zhang X, Zhou D, Lam YY, Ge J
BMC Cardiovasc Disord 2022 Dec 12;22(1):540. doi: 10.1186/s12872-022-02943-9. PMID: 36503424Free PMC Article
Transcatheter aortic valve replacement in bicuspid aortic valve stenosis.
Yoon SH, Webb JG, Leon MB, Makkar R
Prog Cardiovasc Dis 2020 Jul-Aug;63(4):482-487. Epub 2020 Jun 25 doi: 10.1016/j.pcad.2020.06.007. PMID: 32592707
The abnormal contralateral atrioventricular valve in mitral and tricuspid atresia in neonates: An echocardiographic study.
Rydberg A, BarAm S, Teien DE, Vermilion RP, Ludomirsky A
Pediatr Cardiol 1999 May-Jun;20(3):200-2. doi: 10.1007/s002469900440. PMID: 10089244
Morphology of tricuspid valve in pulmonary atresia with intact ventricular septum.
Choi YH, Seo JW, Choi JY, Yun YS, Kim SH, Lee HJ
Pediatr Cardiol 1998 Sep-Oct;19(5):381-9. doi: 10.1007/s002469900333. PMID: 9703562

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