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Abnormal tricuspid valve morphology

MedGen UID:
871267
•Concept ID:
C4025753
•
Anatomical Abnormality
Synonym: Abnormality of the tricuspid valve
 
HPO: HP:0001702

Definition

Any structural anomaly of the tricuspid valve. [from HPO]

Conditions with this feature

Heterotaxy, visceral, 7, autosomal
MedGen UID:
902629
•Concept ID:
C4225217
•
Disease or Syndrome
Autosomal visceral heterotaxy-7 is an autosomal recessive developmental disorder characterized by complex congenital heart malformations and/or situs inversus and caused by defects in the normal left-right asymmetric positioning of internal organs. The phenotype is variable (summary by Guimier et al., 2015). For a discussion of the genetic heterogeneity of visceral heterotaxy, see HTX1 (306955).
See: Condition Record
Heterotaxy, visceral, 7, autosomal

Professional guidelines

PubMed

First trimester genetic sonogram for screening fetal Down syndrome: A population-based study.
Traisrisilp K, Sirichotiyakul S, Tongprasert F, Srisupundit K, Luewan S, Jatavan P, Sirilert S, Tongsong T
Taiwan J Obstet Gynecol 2021 Jul;60(4):706-710. doi: 10.1016/j.tjog.2021.05.021. PMID: 34247811
Echocardiographic criteria to detect unicuspid aortic valve morphology.
Ewen S, Karliova I, Weber P, Schirmer SH, Abdul-Khaliq H, Schöpe J, Mahfoud F, Schäfers HJ
Eur Heart J Cardiovasc Imaging 2019 Jan 1;20(1):40-44. doi: 10.1093/ehjci/jex344. PMID: 29346529
Prenatal diagnosis and outcome of absent pulmonary valve syndrome: contemporary single-center experience and review of the literature.
Wertaschnigg D, Jaeggi M, Chitayat D, Shannon P, Ryan G, Thompson M, Yoo SJ, Jaeggi E
Ultrasound Obstet Gynecol 2013 Feb;41(2):162-7. Epub 2013 Jan 7 doi: 10.1002/uog.11193. PMID: 22605612

Recent clinical studies

Etiology

Ebstein's Anomaly: From Fetus to Adult-Literature Review and Pathway for Patient Care.
Ramcharan TKW, Goff DA, Greenleaf CE, Shebani SO, Salazar JD, Corno AF
Pediatr Cardiol 2022 Oct;43(7):1409-1428. Epub 2022 Apr 23 doi: 10.1007/s00246-022-02908-x. PMID: 35460366
Diagnosis of major heart defects by routine first-trimester ultrasound examination: association with increased nuchal translucency, tricuspid regurgitation and abnormal flow in ductus venosus.
Minnella GP, Crupano FM, Syngelaki A, Zidere V, Akolekar R, Nicolaides KH
Ultrasound Obstet Gynecol 2020 May;55(5):637-644. doi: 10.1002/uog.21956. PMID: 31875326
Anatomy and Physiology of the Tricuspid Valve.
Dahou A, Levin D, Reisman M, Hahn RT
JACC Cardiovasc Imaging 2019 Mar;12(3):458-468. doi: 10.1016/j.jcmg.2018.07.032. PMID: 30846121
Transcatheter Valve Replacement for Right-sided Valve Disease in Congenital Heart Patients.
Gales J, Krasuski RA, Fleming GA
Prog Cardiovasc Dis 2018 Sep-Oct;61(3-4):347-359. Epub 2018 Sep 17 doi: 10.1016/j.pcad.2018.09.003. PMID: 30236750
Evaluation of tricuspid valve morphology and function by transthoracic three-dimensional echocardiography.
Muraru D, Badano LP, Sarais C, Soldà E, Iliceto S
Curr Cardiol Rep 2011 Jun;13(3):242-9. doi: 10.1007/s11886-011-0176-3. PMID: 21365261

Diagnosis

Ebstein's Anomaly: From Fetus to Adult-Literature Review and Pathway for Patient Care.
Ramcharan TKW, Goff DA, Greenleaf CE, Shebani SO, Salazar JD, Corno AF
Pediatr Cardiol 2022 Oct;43(7):1409-1428. Epub 2022 Apr 23 doi: 10.1007/s00246-022-02908-x. PMID: 35460366
The Congenital Tricuspid Valve Spectrum: From Ebstein to Dysplasia.
Stephens EH, Dearani JA, Qureshi MY, Ammash N, Maleszewski JJ
World J Pediatr Congenit Heart Surg 2020 Nov;11(6):783-791. doi: 10.1177/2150135120949235. PMID: 33164686
Ebstein Anomaly in the Adult Patient.
Fuchs MM, Connolly HM
Cardiol Clin 2020 Aug;38(3):353-363. Epub 2020 Jun 6 doi: 10.1016/j.ccl.2020.04.004. PMID: 32622490
Tricuspid Valve Imaging and Intervention in Pediatric and Adult Patients With Congenital Heart Disease.
Qureshi MY, Sommer RJ, Cabalka AK
JACC Cardiovasc Imaging 2019 Apr;12(4):637-651. doi: 10.1016/j.jcmg.2018.10.036. PMID: 30947906
Tricuspid valve disease.
Shah PM, Raney AA
Curr Probl Cardiol 2008 Feb;33(2):47-84. doi: 10.1016/j.cpcardiol.2007.10.004. PMID: 18222317

Therapy

Ebstein's Anomaly.
Holst KA, Connolly HM, Dearani JA
Methodist Debakey Cardiovasc J 2019 Apr-Jun;15(2):138-144. doi: 10.14797/mdcj-15-2-138. PMID: 31384377Free PMC Article
Almost All Incompetent BAV Should Be Repaired.
David TE
Semin Thorac Cardiovasc Surg 2019 Winter;31(4):661-663. Epub 2019 Apr 10 doi: 10.1053/j.semtcvs.2019.03.009. PMID: 30980931
Neonatal Ebstein Anomaly.
Kumar TKS, Boston US, Knott-Craig CJ
Semin Thorac Cardiovasc Surg 2017 Autumn;29(3):331-337. Epub 2017 Sep 25 doi: 10.1053/j.semtcvs.2017.09.006. PMID: 28958645
Reexamining remodeling.
Schäfers HJ, Raddatz A, Schmied W, Takahashi H, Miura Y, Kunihara T, Aicher D
J Thorac Cardiovasc Surg 2015 Feb;149(2 Suppl):S30-6. Epub 2014 Sep 18 doi: 10.1016/j.jtcvs.2014.09.048. PMID: 25439784
Transcatheter aortic valve implantation in bicuspid anatomy.
Zhao ZG, Jilaihawi H, Feng Y, Chen M
Nat Rev Cardiol 2015 Feb;12(2):123-8. Epub 2014 Oct 14 doi: 10.1038/nrcardio.2014.161. PMID: 25311233

Prognosis

Ebstein Anomaly in the Adult Patient.
Fuchs MM, Connolly HM
Cardiol Clin 2020 Aug;38(3):353-363. Epub 2020 Jun 6 doi: 10.1016/j.ccl.2020.04.004. PMID: 32622490
Diagnosis of major heart defects by routine first-trimester ultrasound examination: association with increased nuchal translucency, tricuspid regurgitation and abnormal flow in ductus venosus.
Minnella GP, Crupano FM, Syngelaki A, Zidere V, Akolekar R, Nicolaides KH
Ultrasound Obstet Gynecol 2020 May;55(5):637-644. doi: 10.1002/uog.21956. PMID: 31875326
Tricuspid Valve Imaging and Intervention in Pediatric and Adult Patients With Congenital Heart Disease.
Qureshi MY, Sommer RJ, Cabalka AK
JACC Cardiovasc Imaging 2019 Apr;12(4):637-651. doi: 10.1016/j.jcmg.2018.10.036. PMID: 30947906
Cardiac imaging in Ebstein anomaly.
Qureshi MY, O'Leary PW, Connolly HM
Trends Cardiovasc Med 2018 Aug;28(6):403-409. Epub 2018 Jan 12 doi: 10.1016/j.tcm.2018.01.002. PMID: 29409687
Congenitally corrected transposition.
Wallis GA, Debich-Spicer D, Anderson RH
Orphanet J Rare Dis 2011 May 14;6:22. doi: 10.1186/1750-1172-6-22. PMID: 21569592Free PMC Article

Clinical prediction guides

Diagnosis of major heart defects by routine first-trimester ultrasound examination: association with increased nuchal translucency, tricuspid regurgitation and abnormal flow in ductus venosus.
Minnella GP, Crupano FM, Syngelaki A, Zidere V, Akolekar R, Nicolaides KH
Ultrasound Obstet Gynecol 2020 May;55(5):637-644. doi: 10.1002/uog.21956. PMID: 31875326
Ebstein's Anomaly.
Holst KA, Connolly HM, Dearani JA
Methodist Debakey Cardiovasc J 2019 Apr-Jun;15(2):138-144. doi: 10.14797/mdcj-15-2-138. PMID: 31384377Free PMC Article
MicroRNAs fingerprint of bicuspid aortic valve.
Sabatino J, Wicik Z, De Rosa S, Eyileten C, Jakubik D, Spaccarotella C, Mongiardo A, Postula M, Indolfi C
J Mol Cell Cardiol 2019 Sep;134:98-106. Epub 2019 Jul 3 doi: 10.1016/j.yjmcc.2019.07.001. PMID: 31278905
Tricuspid Valve Imaging and Intervention in Pediatric and Adult Patients With Congenital Heart Disease.
Qureshi MY, Sommer RJ, Cabalka AK
JACC Cardiovasc Imaging 2019 Apr;12(4):637-651. doi: 10.1016/j.jcmg.2018.10.036. PMID: 30947906
Reexamining remodeling.
Schäfers HJ, Raddatz A, Schmied W, Takahashi H, Miura Y, Kunihara T, Aicher D
J Thorac Cardiovasc Surg 2015 Feb;149(2 Suppl):S30-6. Epub 2014 Sep 18 doi: 10.1016/j.jtcvs.2014.09.048. PMID: 25439784

Recent systematic reviews

Clinical outcomes and the impact of valve morphology for transcatheter aortic valve replacement in bicuspid aortic valves: A systematic review and meta-analysis.
Gupta R, Mahmoudi E, Behnoush AH, Malik AH, Mahajan P, Lin M, Bandyopadhyay D, Goel A, Chakraborty S, Aedma SK, Gupta HB, Vyas AV, Combs WG, Mathur M, Yakubov SJ, Patel NC
Catheter Cardiovasc Interv 2023 Oct;102(4):721-730. Epub 2023 Aug 21 doi: 10.1002/ccd.30808. PMID: 37605512
Fetal Tricuspid Regurgitation in the First Trimester as a Screening Marker for Congenital Heart Defects: Systematic Review and Meta-Analysis.
Scala C, Morlando M, Familiari A, Leone Roberti Maggiore U, Ferrero S, D'Antonio F, Khalil A
Fetal Diagn Ther 2017;42(1):1-8. Epub 2017 May 9 doi: 10.1159/000455947. PMID: 28482343
Impact of Valve Morphology on the Prevalence of Coronary Artery Disease: A Systematic Review and Meta-Analysis.
Poggio P, Cavallotti L, Songia P, Di Minno A, Ambrosino P, Mammana L, Parolari A, Alamanni F, Tremoli E, Di Minno MN
J Am Heart Assoc 2016 May 18;5(5) doi: 10.1161/JAHA.116.003200. PMID: 27194004Free PMC Article
Surgical thresholds for bicuspid aortic valve associated aortopathy.
Hardikar AA, Marwick TH
JACC Cardiovasc Imaging 2013 Dec;6(12):1311-20. doi: 10.1016/j.jcmg.2013.10.005. PMID: 24332283
Complex Ebstein's malformation: defining preoperative cardiac anatomy and function.
Negoi RI, Ispas AT, Ghiorghiu I, Filipoiu F, Negoi I, Hostiuc M, Hostiuc S, Ginghina C
J Card Surg 2013 Jan;28(1):70-81. doi: 10.1111/jocs.12032. PMID: 23330581

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