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Recurrent Synovial Sarcoma

MedGen UID:
163190
•Concept ID:
C0855072
•
Neoplastic Process
Synonyms: Relapsed Synovial Sarcoma; Synovial Sarcoma Recurrent

Definition

The reemergence of synovial sarcoma after a period of remission [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Synovial Sarcoma

Professional guidelines

PubMed

Advances in the Management of Pediatric Sarcomas.
Hernandez Tejada FN, Zamudio A, Marques-Piubelli ML, Cuglievan B, Harrison D
Curr Oncol Rep 2020 Nov 16;23(1):3. doi: 10.1007/s11912-020-00995-8. PMID: 33196879
Synovial Sarcoma: Advances in Diagnosis and Treatment Identification of New Biologic Targets to Improve Multimodal Therapy.
El Beaino M, Araujo DM, Lazar AJ, Lin PP
Ann Surg Oncol 2017 Aug;24(8):2145-2154. Epub 2017 Apr 10 doi: 10.1245/s10434-017-5855-x. PMID: 28397189
Vulvar sarcomas: Short guideline for histopathological recognition and clinical management. Part 2.
Chokoeva AA, Tchernev G, Cardoso JC, Patterson JW, Dechev I, Valkanov S, Zanardelli M, Lotti T, Wollina U
Int J Immunopathol Pharmacol 2015 Jun;28(2):178-86. Epub 2015 Mar 26 doi: 10.1177/0394632015575977. PMID: 25816393

Recent clinical studies

Etiology

Synovial sarcoma: the importance of size and location for survival.
Deshmukh R, Mankin HJ, Singer S
Clin Orthop Relat Res 2004 Feb;(419):155-61. PMID: 15021147
Limb salvage in recurrent synovial sarcoma of the right ankle and lower leg.
Sobel E, Giorgini R, Oropeza R, Bapat K, Richardson H
J Am Podiatr Med Assoc 2002 Feb;92(2):90-6. doi: 10.7547/87507315-92-2-90. PMID: 11847260
Surgical treatment of radiation injuries of the hand.
Milanov NO, Shilov BL, Tjulenev AV
Plast Reconstr Surg 1993 Aug;92(2):294-300. doi: 10.1097/00006534-199308000-00015. PMID: 8337280
Aspiration cytology of biphasic and monophasic synovial sarcoma. A report of two cases.
Aisner SC, Seidman JD, Burke KC, Young JW
Acta Cytol 1993 May-Jun;37(3):413-7. PMID: 7684548

Diagnosis

Recurrent Synovial Sarcoma with Breast and Pulmonary Nodule: A Case Report.
Khanal P, Baral B, Pande P, Neupane S, Joshi R
JNMA J Nepal Med Assoc 2024 Jan 2;62(269):52-54. doi: 10.31729/jnma.8408. PMID: 38410005Free PMC Article
Excision of recurrent synovial sarcoma of the infratemporal fossa.
Eravcı FC, Düzlü M, Zorlu ME, Yılmaz M, Ataç MS
Kulak Burun Bogaz Ihtis Derg 2016 Sep-Oct;26(5):293-9. doi: 10.5606/kbbihtisas.2016.09365. PMID: 27888827
Aggressive repeat surgery for a recurrent synovial sarcoma in the pleura.
Nishiyama N, Iwata T, Izumi N, Tsukioka T, Nagano K, Suehiro S
Ann Thorac Cardiovasc Surg 2009 Feb;15(1):46-9. PMID: 19262450
Recurrent primary synovial sarcoma of the chest wall.
Mukhopadhyay S, Aubry MC
J Thorac Oncol 2007 Jul;2(7):660-1. doi: 10.1097/JTO.0b013e31807a2f99. PMID: 17607124
Synovial sarcoma: the importance of size and location for survival.
Deshmukh R, Mankin HJ, Singer S
Clin Orthop Relat Res 2004 Feb;(419):155-61. PMID: 15021147

Therapy

Recurrent Synovial Sarcoma with Breast and Pulmonary Nodule: A Case Report.
Khanal P, Baral B, Pande P, Neupane S, Joshi R
JNMA J Nepal Med Assoc 2024 Jan 2;62(269):52-54. doi: 10.31729/jnma.8408. PMID: 38410005Free PMC Article
Safety and Efficacy of NY-ESO-1 Antigen-Specific T-Cell Receptor Gene-Transduced T Lymphocytes in Patients with Synovial Sarcoma: A Phase I/II Clinical Trial.
Kawai A, Ishihara M, Nakamura T, Kitano S, Iwata S, Takada K, Emori M, Kato K, Endo M, Matsumoto Y, Kakunaga S, Sato E, Miyahara Y, Morino K, Tanaka S, Takahashi S, Matsuo F, Matsumine A, Kageyama S, Ueda T
Clin Cancer Res 2023 Dec 15;29(24):5069-5078. doi: 10.1158/1078-0432.CCR-23-1456. PMID: 37792433Free PMC Article
Trabectedin clinical cases: use according to indication in diverse clinical scenarios.
Grignani G, Martín-Broto J, Schuler M, Reichardt P
Future Oncol 2015;11(11 Suppl):15-24. doi: 10.2217/fon.15.76. PMID: 26043311
Aggressive repeat surgery for a recurrent synovial sarcoma in the pleura.
Nishiyama N, Iwata T, Izumi N, Tsukioka T, Nagano K, Suehiro S
Ann Thorac Cardiovasc Surg 2009 Feb;15(1):46-9. PMID: 19262450
Isolated limb perfusion with rhTNF-alpha and melphalan for locally recurrent childhood synovial sarcoma of the limb.
Hohenberger P, Tunn PU
J Pediatr Hematol Oncol 2003 Nov;25(11):905-9. doi: 10.1097/00043426-200311000-00016. PMID: 14608203

Prognosis

Recurrent Synovial Sarcoma with Breast and Pulmonary Nodule: A Case Report.
Khanal P, Baral B, Pande P, Neupane S, Joshi R
JNMA J Nepal Med Assoc 2024 Jan 2;62(269):52-54. doi: 10.31729/jnma.8408. PMID: 38410005Free PMC Article
Recurrent primary synovial sarcoma of the chest wall.
Mukhopadhyay S, Aubry MC
J Thorac Oncol 2007 Jul;2(7):660-1. doi: 10.1097/JTO.0b013e31807a2f99. PMID: 17607124
Synovial sarcoma: the importance of size and location for survival.
Deshmukh R, Mankin HJ, Singer S
Clin Orthop Relat Res 2004 Feb;(419):155-61. PMID: 15021147
Synovial sarcoma with massive ossification--a case report.
Hara S, Hatori M, Hosaka M, Komatsu T, Tsuchiya T, Kimura N
Ups J Med Sci 2003;108(2):151-8. doi: 10.3109/2000-1967-121. PMID: 14649326
Limb salvage in recurrent synovial sarcoma of the right ankle and lower leg.
Sobel E, Giorgini R, Oropeza R, Bapat K, Richardson H
J Am Podiatr Med Assoc 2002 Feb;92(2):90-6. doi: 10.7547/87507315-92-2-90. PMID: 11847260

Clinical prediction guides

Excision of recurrent synovial sarcoma of the infratemporal fossa.
Eravcı FC, Düzlü M, Zorlu ME, Yılmaz M, Ataç MS
Kulak Burun Bogaz Ihtis Derg 2016 Sep-Oct;26(5):293-9. doi: 10.5606/kbbihtisas.2016.09365. PMID: 27888827
Synovial sarcoma: the importance of size and location for survival.
Deshmukh R, Mankin HJ, Singer S
Clin Orthop Relat Res 2004 Feb;(419):155-61. PMID: 15021147
Isolated limb perfusion with rhTNF-alpha and melphalan for locally recurrent childhood synovial sarcoma of the limb.
Hohenberger P, Tunn PU
J Pediatr Hematol Oncol 2003 Nov;25(11):905-9. doi: 10.1097/00043426-200311000-00016. PMID: 14608203

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