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Decreased circulating glycerol level

MedGen UID:
1639424
•Concept ID:
C4703542
•
Finding
HPO: HP:0031794

Definition

A decrease below the normal concentration of glycerol in the blood. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDecreased circulating glycerol level

Professional guidelines

PubMed

The Impact of Intra-Arterial Papaverine-Hydrochloride on Cerebral Metabolism and Oxygenation for Treatment of Delayed-Onset Post-Subarachnoid Hemorrhage Vasospasm.
Hosmann A, Wang WT, Dodier P, Bavinzski G, Engel A, Herta J, Plöchl W, Reinprecht A, Gruber A
Neurosurgery 2020 Sep 15;87(4):712-719. doi: 10.1093/neuros/nyz500. PMID: 31792510
Metabolism in adipose tissue in response to citalopram and trimipramine treatment--an in situ microdialysis study.
Flechtner-Mors M, Jenkinson CP, Alt A, Adler G, Ditschuneit HH
J Psychiatr Res 2008 Jun;42(7):578-86. Epub 2007 Aug 9 doi: 10.1016/j.jpsychires.2007.06.003. PMID: 17692337
Impact of 2 weeks high dose growth hormone treatment on basal and insulin stimulated substrate metabolism in humans.
Møller N, Møller J, Jørgensen JO, Ovesen P, Schmitz O, Alberti KG, Christiansen JS
Clin Endocrinol (Oxf) 1993 Nov;39(5):577-81. doi: 10.1111/j.1365-2265.1993.tb02412.x. PMID: 8252748

Recent clinical studies

Etiology

SGLT1 and SGLT2 inhibition, circulating metabolites, and cerebral small vessel disease: a mediation Mendelian Randomization study.
Lv Y, Cheng X, Dong Q
Cardiovasc Diabetol 2024 May 7;23(1):157. doi: 10.1186/s12933-024-02255-6. PMID: 38715111Free PMC Article
Menopause modulates the circulating metabolome: evidence from a prospective cohort study.
Karppinen JE, Törmäkangas T, Kujala UM, Sipilä S, Laukkanen J, Aukee P, Kovanen V, Laakkonen EK
Eur J Prev Cardiol 2022 Aug 5;29(10):1448-1459. doi: 10.1093/eurjpc/zwac060. PMID: 35930503
Dynamics of appearance and decay of gaseous microemboli during in vitro extracorporeal circulation.
Harea GT, Karaliou V, Roberts TR, Choi JH, Beely BM, Cancio LC, Batchinsky AI
Perfusion 2022 Apr;37(3):242-248. Epub 2021 Feb 10 doi: 10.1177/0267659121991423. PMID: 33567967
Lifestyle-Intervention-Induced Reduction of Abdominal Fat Is Reflected by a Decreased Circulating Glycerol Level and an Increased HDL Diameter.
Beekman M, Schutte BAM, Akker EBVD, Noordam R, Dibbets-Schneider P, de Geus-Oei LF, Deelen J, Rest OV, Heemst DV, Feskens EJM, Slagboom PE
Mol Nutr Food Res 2020 May;64(10):e1900818. Epub 2020 Apr 23 doi: 10.1002/mnfr.201900818. PMID: 32271991Free PMC Article
Modulation of oxidative stress, inflammation, and atherosclerosis by lipoprotein-associated phospholipase A2.
Rosenson RS, Stafforini DM
J Lipid Res 2012 Sep;53(9):1767-82. Epub 2012 Jun 4 doi: 10.1194/jlr.R024190. PMID: 22665167Free PMC Article

Diagnosis

SGLT1 and SGLT2 inhibition, circulating metabolites, and cerebral small vessel disease: a mediation Mendelian Randomization study.
Lv Y, Cheng X, Dong Q
Cardiovasc Diabetol 2024 May 7;23(1):157. doi: 10.1186/s12933-024-02255-6. PMID: 38715111Free PMC Article
Research progress of fibroblast growth factor 23 in acute kidney injury.
Zhang L, Qin W
Pediatr Nephrol 2023 Jul;38(7):2013-2022. Epub 2022 Nov 22 doi: 10.1007/s00467-022-05791-z. PMID: 36416954Free PMC Article
Effects of diet and hyperlipidemia on levels and distribution of circulating lysophosphatidic acid.
Kraemer MP, Mao G, Hammill C, Yan B, Li Y, Onono F, Smyth SS, Morris AJ
J Lipid Res 2019 Nov;60(11):1818-1828. Epub 2019 Sep 4 doi: 10.1194/jlr.M093096. PMID: 31484695Free PMC Article
Adipose-Derived Fatty Acid-Binding Proteins Plasma Concentrations Are Increased in Breast Cancer Patients.
Guaita-Esteruelas S, Saavedra-García P, Bosquet A, Borràs J, Girona J, Amiliano K, Rodríguez-Balada M, Heras M, Masana L, Gumà J
Oncologist 2017 Nov;22(11):1309-1315. Epub 2017 Jul 12 doi: 10.1634/theoncologist.2016-0483. PMID: 28701570Free PMC Article
Regulatory role for the arginine-nitric oxide pathway in metabolism of energy substrates.
Jobgen WS, Fried SK, Fu WJ, Meininger CJ, Wu G
J Nutr Biochem 2006 Sep;17(9):571-88. Epub 2006 Jan 9 doi: 10.1016/j.jnutbio.2005.12.001. PMID: 16524713

Therapy

SGLT1 and SGLT2 inhibition, circulating metabolites, and cerebral small vessel disease: a mediation Mendelian Randomization study.
Lv Y, Cheng X, Dong Q
Cardiovasc Diabetol 2024 May 7;23(1):157. doi: 10.1186/s12933-024-02255-6. PMID: 38715111Free PMC Article
Dynamics of appearance and decay of gaseous microemboli during in vitro extracorporeal circulation.
Harea GT, Karaliou V, Roberts TR, Choi JH, Beely BM, Cancio LC, Batchinsky AI
Perfusion 2022 Apr;37(3):242-248. Epub 2021 Feb 10 doi: 10.1177/0267659121991423. PMID: 33567967
Lifestyle-Intervention-Induced Reduction of Abdominal Fat Is Reflected by a Decreased Circulating Glycerol Level and an Increased HDL Diameter.
Beekman M, Schutte BAM, Akker EBVD, Noordam R, Dibbets-Schneider P, de Geus-Oei LF, Deelen J, Rest OV, Heemst DV, Feskens EJM, Slagboom PE
Mol Nutr Food Res 2020 May;64(10):e1900818. Epub 2020 Apr 23 doi: 10.1002/mnfr.201900818. PMID: 32271991Free PMC Article
Modulation of oxidative stress, inflammation, and atherosclerosis by lipoprotein-associated phospholipase A2.
Rosenson RS, Stafforini DM
J Lipid Res 2012 Sep;53(9):1767-82. Epub 2012 Jun 4 doi: 10.1194/jlr.R024190. PMID: 22665167Free PMC Article
Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans.
Timmers S, Konings E, Bilet L, Houtkooper RH, van de Weijer T, Goossens GH, Hoeks J, van der Krieken S, Ryu D, Kersten S, Moonen-Kornips E, Hesselink MKC, Kunz I, Schrauwen-Hinderling VB, Blaak E, Auwerx J, Schrauwen P
Cell Metab 2011 Nov 2;14(5):612-22. doi: 10.1016/j.cmet.2011.10.002. PMID: 22055504Free PMC Article

Prognosis

SGLT1 and SGLT2 inhibition, circulating metabolites, and cerebral small vessel disease: a mediation Mendelian Randomization study.
Lv Y, Cheng X, Dong Q
Cardiovasc Diabetol 2024 May 7;23(1):157. doi: 10.1186/s12933-024-02255-6. PMID: 38715111Free PMC Article
Research progress of fibroblast growth factor 23 in acute kidney injury.
Zhang L, Qin W
Pediatr Nephrol 2023 Jul;38(7):2013-2022. Epub 2022 Nov 22 doi: 10.1007/s00467-022-05791-z. PMID: 36416954Free PMC Article
Adipose-Derived Fatty Acid-Binding Proteins Plasma Concentrations Are Increased in Breast Cancer Patients.
Guaita-Esteruelas S, Saavedra-García P, Bosquet A, Borràs J, Girona J, Amiliano K, Rodríguez-Balada M, Heras M, Masana L, Gumà J
Oncologist 2017 Nov;22(11):1309-1315. Epub 2017 Jul 12 doi: 10.1634/theoncologist.2016-0483. PMID: 28701570Free PMC Article
Evaluation of plasma-free endocannabinoids and their congeners in abstinent cocaine addicts seeking outpatient treatment: impact of psychiatric co-morbidity.
Pavón FJ, Araos P, Pastor A, Calado M, Pedraz M, Campos-Cloute R, Ruiz JJ, Serrano A, Blanco E, Rivera P, Suárez J, Romero-Cuevas M, Pujadas M, Vergara-Moragues E, Gornemann I, Torrens M, de la Torre R, Rodríguez de Fonseca F
Addict Biol 2013 Nov;18(6):955-69. Epub 2013 Nov 14 doi: 10.1111/adb.12107. PMID: 24283982
Human intraperitoneal microdialysis: increased lactate/pyruvate ratio suggests early visceral ischaemia. A pilot study.
Jansson K, Ungerstedt J, Jonsson T, Redler B, Andersson M, Ungerstedt U, Norgren L
Scand J Gastroenterol 2003 Sep;38(9):1007-11. doi: 10.1080/00365520310004065. PMID: 14531543

Clinical prediction guides

SGLT1 and SGLT2 inhibition, circulating metabolites, and cerebral small vessel disease: a mediation Mendelian Randomization study.
Lv Y, Cheng X, Dong Q
Cardiovasc Diabetol 2024 May 7;23(1):157. doi: 10.1186/s12933-024-02255-6. PMID: 38715111Free PMC Article
Plasma endocannabinoids and cannabimimetic fatty acid derivatives are altered in gastroparesis: A sex- and subtype-dependent observation.
Bashashati M, Leishman E, Bradshaw H, Sigaroodi S, Tatro E, Bright T, McCallum R, Sarosiek I
Neurogastroenterol Motil 2021 Jan;33(1):e13961. Epub 2020 Aug 10 doi: 10.1111/nmo.13961. PMID: 32779297Free PMC Article
Effects of diet and hyperlipidemia on levels and distribution of circulating lysophosphatidic acid.
Kraemer MP, Mao G, Hammill C, Yan B, Li Y, Onono F, Smyth SS, Morris AJ
J Lipid Res 2019 Nov;60(11):1818-1828. Epub 2019 Sep 4 doi: 10.1194/jlr.M093096. PMID: 31484695Free PMC Article
Modulation of oxidative stress, inflammation, and atherosclerosis by lipoprotein-associated phospholipase A2.
Rosenson RS, Stafforini DM
J Lipid Res 2012 Sep;53(9):1767-82. Epub 2012 Jun 4 doi: 10.1194/jlr.R024190. PMID: 22665167Free PMC Article
Renal perfusion and metabolism in experimental endotoxin shock.
Gullichsen E
Acta Chir Scand Suppl 1991;560:7-31. PMID: 1828126

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