U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Acral Edema

MedGen UID:
1760647
•Concept ID:
C5418862
•
Pathologic Function

Definition

Accumulation of an excessive amount of watery fluid in cells or intercellular tissues of the hands and feet. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAcral Edema

Recent clinical studies

Etiology

Sudden Conjunctivitis, Lymphopenia, and Rash Combined With Hemodynamic Changes (SCoRCH) After Trimethoprim-Sulfamethoxazole Use: A Case Series Study of a Hypersensitivity Reaction.
O'Brian M, Rose EK, Mauskar MM, Dominguez AR
JAMA Dermatol 2023 Jan 1;159(1):73-78. doi: 10.1001/jamadermatol.2022.4657. PMID: 36350597Free PMC Article
Mucocutaneous disease and related clinical characteristics in hospitalized children and adolescents with COVID-19 and multisystem inflammatory syndrome in children.
Rekhtman S, Tannenbaum R, Strunk A, Birabaharan M, Wright S, Garg A
J Am Acad Dermatol 2021 Feb;84(2):408-414. Epub 2020 Oct 24 doi: 10.1016/j.jaad.2020.10.060. PMID: 33323343Free PMC Article
Dermatologic findings in 16 patients with Cockayne syndrome and cerebro-oculo-facial-skeletal syndrome.
Frouin E, Laugel V, Durand M, Dollfus H, Lipsker D
JAMA Dermatol 2013 Dec;149(12):1414-8. doi: 10.1001/jamadermatol.2013.6683. PMID: 24154677
"Urticaria multiforme": a case series and review of acute annular urticarial hypersensitivity syndromes in children.
Shah KN, Honig PJ, Yan AC
Pediatrics 2007 May;119(5):e1177-83. doi: 10.1542/peds.2006-1553. PMID: 17470565

Diagnosis

Sudden Conjunctivitis, Lymphopenia, and Rash Combined With Hemodynamic Changes (SCoRCH) After Trimethoprim-Sulfamethoxazole Use: A Case Series Study of a Hypersensitivity Reaction.
O'Brian M, Rose EK, Mauskar MM, Dominguez AR
JAMA Dermatol 2023 Jan 1;159(1):73-78. doi: 10.1001/jamadermatol.2022.4657. PMID: 36350597Free PMC Article
Acute Hemorrhagic Edema of Infancy: A Diagnostic Challenge for the General Pediatrician.
Leung AKC, Leong KF, Lam JM
Curr Pediatr Rev 2020;16(4):285-293. doi: 10.2174/1573396316666200727145039. PMID: 32718294
Delayed aminopenicillin reaction associated to human herpes virus 6 infection mimicking DRESS syndrome.
Míguez-Martín L, Higelmo-Gómez H, Gómez-Farpón Á, Álvarez-Caro F
Rev Alerg Mex 2019 Jul-Sep;66(3):375-378. doi: 10.29262/ram.v66i3.540. PMID: 31606023
"Urticaria multiforme": a case series and review of acute annular urticarial hypersensitivity syndromes in children.
Shah KN, Honig PJ, Yan AC
Pediatrics 2007 May;119(5):e1177-83. doi: 10.1542/peds.2006-1553. PMID: 17470565
Erythromelalgia misdiagnosed as cellulitis.
Eaton M, Murphy S
Cutis 2005 Jan;75(1):37-40. PMID: 15732433

Therapy

Sudden Conjunctivitis, Lymphopenia, and Rash Combined With Hemodynamic Changes (SCoRCH) After Trimethoprim-Sulfamethoxazole Use: A Case Series Study of a Hypersensitivity Reaction.
O'Brian M, Rose EK, Mauskar MM, Dominguez AR
JAMA Dermatol 2023 Jan 1;159(1):73-78. doi: 10.1001/jamadermatol.2022.4657. PMID: 36350597Free PMC Article
Acute Hemorrhagic Edema of Infancy: A Diagnostic Challenge for the General Pediatrician.
Leung AKC, Leong KF, Lam JM
Curr Pediatr Rev 2020;16(4):285-293. doi: 10.2174/1573396316666200727145039. PMID: 32718294
Delayed aminopenicillin reaction associated to human herpes virus 6 infection mimicking DRESS syndrome.
Míguez-Martín L, Higelmo-Gómez H, Gómez-Farpón Á, Álvarez-Caro F
Rev Alerg Mex 2019 Jul-Sep;66(3):375-378. doi: 10.29262/ram.v66i3.540. PMID: 31606023
Dermatologic findings in 16 patients with Cockayne syndrome and cerebro-oculo-facial-skeletal syndrome.
Frouin E, Laugel V, Durand M, Dollfus H, Lipsker D
JAMA Dermatol 2013 Dec;149(12):1414-8. doi: 10.1001/jamadermatol.2013.6683. PMID: 24154677
Remitting seronegative symmetrical synovitis with pitting edema in leprosy.
Helling CA, Locursio A, Manzur ME, Sormani de Fonseca ML
Clin Rheumatol 2006 Feb;25(1):95-7. Epub 2005 Sep 21 doi: 10.1007/s10067-005-1145-2. PMID: 16175431

Prognosis

Mucocutaneous disease and related clinical characteristics in hospitalized children and adolescents with COVID-19 and multisystem inflammatory syndrome in children.
Rekhtman S, Tannenbaum R, Strunk A, Birabaharan M, Wright S, Garg A
J Am Acad Dermatol 2021 Feb;84(2):408-414. Epub 2020 Oct 24 doi: 10.1016/j.jaad.2020.10.060. PMID: 33323343Free PMC Article
Infantile acute hemorrhagic edema of the skin.
Paradisi M, Annessi G, Corrado A
Cutis 2001 Aug;68(2):127-9. PMID: 11534914

Clinical prediction guides

Mucocutaneous disease and related clinical characteristics in hospitalized children and adolescents with COVID-19 and multisystem inflammatory syndrome in children.
Rekhtman S, Tannenbaum R, Strunk A, Birabaharan M, Wright S, Garg A
J Am Acad Dermatol 2021 Feb;84(2):408-414. Epub 2020 Oct 24 doi: 10.1016/j.jaad.2020.10.060. PMID: 33323343Free PMC Article
Acute Hemorrhagic Edema of Infancy: A Diagnostic Challenge for the General Pediatrician.
Leung AKC, Leong KF, Lam JM
Curr Pediatr Rev 2020;16(4):285-293. doi: 10.2174/1573396316666200727145039. PMID: 32718294
Dermatologic findings in 16 patients with Cockayne syndrome and cerebro-oculo-facial-skeletal syndrome.
Frouin E, Laugel V, Durand M, Dollfus H, Lipsker D
JAMA Dermatol 2013 Dec;149(12):1414-8. doi: 10.1001/jamadermatol.2013.6683. PMID: 24154677

Supplemental Content

Table of contents

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...