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Benign Oral Cavity Soft Tissue Neoplasm

MedGen UID:
1771343
•Concept ID:
C5420226
•
Neoplastic Process

Definition

A mesenchymal neoplasm that arises from the oral cavity and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign Oral Cavity Soft Tissue Neoplasm

Professional guidelines

PubMed

Use of refrigerant spray of a propane/butane/isobutane gas mixture in the management of keratocystic odontogenic tumors: a preliminary study.
de Souza Cruz EL, da Silva Tabosa AK, Falcão AS, Tartari T, de Menezes LM, da Costa ET, Júnior JT
Oral Maxillofac Surg 2017 Mar;21(1):21-26. Epub 2016 Nov 21 doi: 10.1007/s10006-016-0591-0. PMID: 27873145
Clinical features and management of oral and maxillofacial tumors in children.
Tanaka N, Murata A, Yamaguchi A, Kohama G
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999 Jul;88(1):11-5. doi: 10.1016/s1079-2104(99)70186-1. PMID: 10442938
Differential diagnosis of oral enlargements in children.
Flaitz CM, Coleman GC
Pediatr Dent 1995 Jul-Aug;17(4):294-300. PMID: 7567634

Recent clinical studies

Etiology

Fusion genes aiding the diagnosis of soft tissue tumours of the oral cavity: From bench to bedside.
Gomes IP, Guimarães LM, Gomez RS, Gomes CC
J Oral Pathol Med 2023 Aug;52(7):575-582. Epub 2023 Apr 17 doi: 10.1111/jop.13429. PMID: 36945188
Metastatic Tumors to the Oral Soft Tissues and Jawbones: A Retrospective Analysis of 40 Cases and Review of the Literature.
Ho DP, Wilkinson PE, Vogel RI, Gopalakrishnan R, Argyris PP
Head Neck Pathol 2022 Sep;16(3):802-813. Epub 2022 Apr 19 doi: 10.1007/s12105-022-01451-8. PMID: 35438419Free PMC Article
Pediatric Benign Soft Tissue Oral and Maxillofacial Pathology.
Glickman A, Karlis V
Oral Maxillofac Surg Clin North Am 2016 Feb;28(1):1-10. doi: 10.1016/j.coms.2015.07.005. PMID: 26614696
Reactive hyperplasias,precancerous and malignant lesions of the oral mucosa.
Krahl D, Altenburg A, Zouboulis CC
J Dtsch Dermatol Ges 2008 Mar;6(3):217-32. doi: 10.1111/j.1610-0387.2007.06625.x. PMID: 18315622
Fibromatosis of the oral and paraoral region.
Fowler CB, Hartman KS, Brannon RB
Oral Surg Oral Med Oral Pathol 1994 Apr;77(4):373-86. doi: 10.1016/0030-4220(94)90200-3. PMID: 8015802

Diagnosis

Osteolipoma of head and neck - a review.
Wong BLK, Hogan C
Braz J Otorhinolaryngol 2022 Nov-Dec;88 Suppl 4(Suppl 4):S177-S187. Epub 2022 May 20 doi: 10.1016/j.bjorl.2022.04.002. PMID: 35659712Free PMC Article
Osteochondrolipoma of the Hand.
Van Demark RE Jr, Fiegen T, Hayes M, Hayes M, Sunassee A, Helsper E
J Hand Surg Am 2022 Sep;47(9):904.e1-904.e4. Epub 2021 Jul 24 doi: 10.1016/j.jhsa.2021.05.024. PMID: 34312026
Oral radiation-induced sarcomas: Systematic review.
de Souza LL, Pontes HAR, Santos-Silva AR, Fernandes LA, Batista LAL, Lopes MA, Khan W, Pontes FSC
Head Neck 2020 Sep;42(9):2660-2668. Epub 2020 Apr 28 doi: 10.1002/hed.26176. PMID: 32343457
Pediatric Benign Soft Tissue Oral and Maxillofacial Pathology.
Glickman A, Karlis V
Oral Maxillofac Surg Clin North Am 2016 Feb;28(1):1-10. doi: 10.1016/j.coms.2015.07.005. PMID: 26614696
Congenital epulis.
Merglová V, Mukensnabl P, Andrle P
BMJ Case Rep 2012 Jul 9;2012 doi: 10.1136/bcr.01.2012.5483. PMID: 22778448Free PMC Article

Therapy

Efficacy of Ultrasound Shear Wave Elastography in the Diagnosis of Salivary Gland Tumors.
Abba M, Allon I, Markovich-Roth T, Abramson A, London D
J Oral Maxillofac Surg 2023 Jun;81(6):780-789. Epub 2023 Mar 9 doi: 10.1016/j.joms.2023.03.001. PMID: 36972729
Oral mucosal findings related to tobacco use and alcohol consumption: a study on Swiss army recruits involving self-reported and clinical data.
Morger R, Ramseier CA, Rees TD, Bürgin WB, Bornstein MM
Oral Health Prev Dent 2010;8(2):143-51. PMID: 20589248
Focal myositis of the tongue presenting as macroglossia.
Lee MW, Huh JR, Lee WJ, Choi JH, Moon KC, Koh JK
Clin Exp Dermatol 2009 Dec;34(8):e869-72. doi: 10.1111/j.1365-2230.2009.03626.x. PMID: 20055851
Use of carbon dioxide laser in the therapy of benign oral soft-tissue lesions.
Dunsche A, Fleiner B, Terheyden H, Hoffmeister B
Adv Otorhinolaryngol 1995;49:136-9. doi: 10.1159/000424357. PMID: 7653348
Fibular and iliac crest osteomuscular free flap reconstruction of the oral cavity.
Haughey BH, Fredrickson JM, Lerrick AJ, Sclaroff A, Gay WD
Laryngoscope 1994 Nov;104(11 Pt 1):1305-13. doi: 10.1288/00005537-199411000-00001. PMID: 7968158

Prognosis

Osteolipoma of head and neck - a review.
Wong BLK, Hogan C
Braz J Otorhinolaryngol 2022 Nov-Dec;88 Suppl 4(Suppl 4):S177-S187. Epub 2022 May 20 doi: 10.1016/j.bjorl.2022.04.002. PMID: 35659712Free PMC Article
Metastatic Tumors to the Oral Soft Tissues and Jawbones: A Retrospective Analysis of 40 Cases and Review of the Literature.
Ho DP, Wilkinson PE, Vogel RI, Gopalakrishnan R, Argyris PP
Head Neck Pathol 2022 Sep;16(3):802-813. Epub 2022 Apr 19 doi: 10.1007/s12105-022-01451-8. PMID: 35438419Free PMC Article
Oral radiation-induced sarcomas: Systematic review.
de Souza LL, Pontes HAR, Santos-Silva AR, Fernandes LA, Batista LAL, Lopes MA, Khan W, Pontes FSC
Head Neck 2020 Sep;42(9):2660-2668. Epub 2020 Apr 28 doi: 10.1002/hed.26176. PMID: 32343457
Composite hemangioendothelioma: clinical and histologic features of an enigmatic entity.
Shang Leen SL, Fisher C, Thway K
Adv Anat Pathol 2015 Jul;22(4):254-9. doi: 10.1097/PAP.0000000000000079. PMID: 26050262
Malignant tumors of the oral cavity and oropharynx: clinical, pathologic, and radiologic evaluation.
Weber AL, Romo L, Hashmi S
Neuroimaging Clin N Am 2003 Aug;13(3):443-64. doi: 10.1016/s1052-5149(03)00037-6. PMID: 14631684

Clinical prediction guides

Efficacy of Ultrasound Shear Wave Elastography in the Diagnosis of Salivary Gland Tumors.
Abba M, Allon I, Markovich-Roth T, Abramson A, London D
J Oral Maxillofac Surg 2023 Jun;81(6):780-789. Epub 2023 Mar 9 doi: 10.1016/j.joms.2023.03.001. PMID: 36972729
Osteolipoma: a review of the literature and a rare case report.
Cakir Karabas H, Ozcan I, Soluk Tekkesin M, Isler SC
Oral Radiol 2021 Oct;37(4):560-565. Epub 2021 Jan 11 doi: 10.1007/s11282-020-00500-8. PMID: 33428104
Chondroma of the Tongue.
Dimitrijevic MV, Sopta J, Ivisevic TB, Dudvarski Z
J Craniofac Surg 2019 Jun;30(4):e315-e317. doi: 10.1097/SCS.0000000000005230. PMID: 30845089
Granular cell tumor in two oral anatomic sites.
Serpa MS, Costa-Neto H, de Oliveira PT, da Silveira ÉJ, de Medeiros AM
Eur Arch Otorhinolaryngol 2016 Oct;273(10):3439-41. Epub 2016 Mar 23 doi: 10.1007/s00405-016-4006-5. PMID: 27007285
Fibromatosis of the oral and paraoral region.
Fowler CB, Hartman KS, Brannon RB
Oral Surg Oral Med Oral Pathol 1994 Apr;77(4):373-86. doi: 10.1016/0030-4220(94)90200-3. PMID: 8015802

Recent systematic reviews

Oral radiation-induced sarcomas: Systematic review.
de Souza LL, Pontes HAR, Santos-Silva AR, Fernandes LA, Batista LAL, Lopes MA, Khan W, Pontes FSC
Head Neck 2020 Sep;42(9):2660-2668. Epub 2020 Apr 28 doi: 10.1002/hed.26176. PMID: 32343457

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