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Uterine disorder

MedGen UID:
22590
•Concept ID:
C0042131
•
Disease or Syndrome
Synonym: Uterine disease
SNOMED CT: Uterine disease (12337004); Uterine disorder (12337004); Disorder of uterus (12337004)
 
Monarch Initiative: MONDO:0002654

Definition

A non-neoplastic or neoplastic disorder that affects the uterine corpus or the cervix. Representative examples of non-neoplastic disorders include endometritis and cervicitis. Representative examples of neoplastic disorders include endometrial carcinoma, carcinosarcoma, and cervical carcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUterine disorder

Professional guidelines

PubMed

Management of Symptomatic Uterine Leiomyomas: ACOG Practice Bulletin, Number 228.
Obstet Gynecol 2021 Jun 1;137(6):e100-e115. doi: 10.1097/AOG.0000000000004401. PMID: 34011888
NRG Oncology/RTOG Consensus Guidelines for Delineation of Clinical Target Volume for Intensity Modulated Pelvic Radiation Therapy in Postoperative Treatment of Endometrial and Cervical Cancer: An Update.
Small W Jr, Bosch WR, Harkenrider MM, Strauss JB, Abu-Rustum N, Albuquerque KV, Beriwal S, Creutzberg CL, Eifel PJ, Erickson BA, Fyles AW, Hentz CL, Jhingran A, Klopp AH, Kunos CA, Mell LK, Portelance L, Powell ME, Viswanathan AN, Yacoub JH, Yashar CM, Winter KA, Gaffney DK
Int J Radiat Oncol Biol Phys 2021 Feb 1;109(2):413-424. Epub 2020 Sep 6 doi: 10.1016/j.ijrobp.2020.08.061. PMID: 32905846Free PMC Article
Uterine Fibroids: Diagnosis and Treatment.
De La Cruz MS, Buchanan EM
Am Fam Physician 2017 Jan 15;95(2):100-107. PMID: 28084714

Recent clinical studies

Etiology

Adenomyosis in Pregnancy: Diagnostic Pearls and Pitfalls.
Jensen KK, Pyle C, Foster BR, Sohaey R, Oh KY
Radiographics 2021 May-Jun;41(3):929-944. Epub 2021 Mar 26 doi: 10.1148/rg.2021200120. PMID: 33769889
Adenomyosis and infertility: the role of the junctional zone.
Barbanti C, Centini G, Lazzeri L, Habib N, Labanca L, Zupi E, Afors K, Starace AC
Gynecol Endocrinol 2021 Jul;37(7):577-583. Epub 2021 Feb 15 doi: 10.1080/09513590.2021.1878131. PMID: 33587014
Diagnosing adenomyosis: an integrated clinical and imaging approach.
Chapron C, Vannuccini S, Santulli P, Abrão MS, Carmona F, Fraser IS, Gordts S, Guo SW, Just PA, Noël JC, Pistofidis G, Van den Bosch T, Petraglia F
Hum Reprod Update 2020 Apr 15;26(3):392-411. doi: 10.1093/humupd/dmz049. PMID: 32097456
Recent advances in understanding and managing adenomyosis.
Vannuccini S, Petraglia F
F1000Res 2019;8 Epub 2019 Mar 13 doi: 10.12688/f1000research.17242.1. PMID: 30918629Free PMC Article
Expression of Inflammatory and Neurogenic Mediators in Adenomyosis.
Carrarelli P, Yen CF, Funghi L, Arcuri F, Tosti C, Bifulco G, Luddi A, Lee CL, Petraglia F
Reprod Sci 2017 Mar;24(3):369-375. Epub 2016 Jul 20 doi: 10.1177/1933719116657192. PMID: 27440813

Diagnosis

Adenomyosis at a Glance: An Integrated Review of Transvaginal Ultrasound and MR Imaging Findings.
Janicas C, Cunha TM
Curr Probl Diagn Radiol 2023 Sep-Oct;52(5):412-417. Epub 2023 May 11 doi: 10.1067/j.cpradiol.2023.05.007. PMID: 37230885
Diagnosing adenomyosis: an integrated clinical and imaging approach.
Chapron C, Vannuccini S, Santulli P, Abrão MS, Carmona F, Fraser IS, Gordts S, Guo SW, Just PA, Noël JC, Pistofidis G, Van den Bosch T, Petraglia F
Hum Reprod Update 2020 Apr 15;26(3):392-411. doi: 10.1093/humupd/dmz049. PMID: 32097456
Recent advances in understanding and managing adenomyosis.
Vannuccini S, Petraglia F
F1000Res 2019;8 Epub 2019 Mar 13 doi: 10.12688/f1000research.17242.1. PMID: 30918629Free PMC Article
Pathogenesis of uterine adenomyosis: invagination or metaplasia?
García-Solares J, Donnez J, Donnez O, Dolmans MM
Fertil Steril 2018 Mar;109(3):371-379. doi: 10.1016/j.fertnstert.2017.12.030. PMID: 29566849
Pathogenesis of adenomyosis: an update on molecular mechanisms.
Vannuccini S, Tosti C, Carmona F, Huang SJ, Chapron C, Guo SW, Petraglia F
Reprod Biomed Online 2017 Nov;35(5):592-601. Epub 2017 Jun 27 doi: 10.1016/j.rbmo.2017.06.016. PMID: 28693952

Therapy

Hormonal treatments for endometriosis: The endocrine background.
Vannuccini S, Clemenza S, Rossi M, Petraglia F
Rev Endocr Metab Disord 2022 Jun;23(3):333-355. Epub 2021 Aug 17 doi: 10.1007/s11154-021-09666-w. PMID: 34405378Free PMC Article

Prognosis

Key drivers of hysterectomy among women of reproductive age in three states in India: comparative evidence from NFHS-4 and NFHS-5.
Singh SK, Chauhan K, Tripathi V
BMC Womens Health 2024 Feb 9;24(1):107. doi: 10.1186/s12905-024-02886-7. PMID: 38336664Free PMC Article

Clinical prediction guides

Key drivers of hysterectomy among women of reproductive age in three states in India: comparative evidence from NFHS-4 and NFHS-5.
Singh SK, Chauhan K, Tripathi V
BMC Womens Health 2024 Feb 9;24(1):107. doi: 10.1186/s12905-024-02886-7. PMID: 38336664Free PMC Article
Adenomyosis and infertility: the role of the junctional zone.
Barbanti C, Centini G, Lazzeri L, Habib N, Labanca L, Zupi E, Afors K, Starace AC
Gynecol Endocrinol 2021 Jul;37(7):577-583. Epub 2021 Feb 15 doi: 10.1080/09513590.2021.1878131. PMID: 33587014
Diagnosing adenomyosis: an integrated clinical and imaging approach.
Chapron C, Vannuccini S, Santulli P, Abrão MS, Carmona F, Fraser IS, Gordts S, Guo SW, Just PA, Noël JC, Pistofidis G, Van den Bosch T, Petraglia F
Hum Reprod Update 2020 Apr 15;26(3):392-411. doi: 10.1093/humupd/dmz049. PMID: 32097456
Change in the ovarian environment after hysterectomy with bilateral salpingectomy: is it the technique or surgery itself?
Atalay MA, Cetinkaya Demir B, Ozerkan K
Eur J Obstet Gynecol Reprod Biol 2016 Sep;204:57-61. Epub 2016 Aug 4 doi: 10.1016/j.ejogrb.2016.07.483. PMID: 27522244

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