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Intermediate Lipomatous Neoplasm

MedGen UID:: 232652
•Concept ID:: C1334217
•: Neoplastic Process

Definition

A lipomatous neoplasm characterized by a high risk of local recurrence and no risk of metastasis. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVIntermediate Lipomatous Neoplasm

Disease
- Disorder by Site
  - Connective and Soft Tissue Disorder
    - Connective and soft tissue neoplasm
      - Soft tissue neoplasm
        Intermediate Soft Tissue Neoplasm
        Intermediate Lipomatous Neoplasm
        Atypical lipomatous tumor
        Atypical Lipomatous Tumor/Well Differentiated Liposarcoma of Deep Soft Tissue
        Inflammatory liposarcoma
        Sclerosing liposarcoma
        Skin Atypical Lipomatous Tumor/Well Differentiated Liposarcoma
        Superficial Atypical Lipomatous Tumor/Well Differentiated Liposarcoma
        Well-differentiated liposarcoma

Professional guidelines

PubMed

Magnetic resonance imaging of trunk and extremity myxoid liposarcoma: diagnosis, staging, and response to treatment.

Saifuddin A, Andrei V, Rajakulasingam R, Oliveira I, Seddon B
Skeletal Radiol 2021 Oct;50(10):1963-1980. Epub 2021 Apr 1 doi: 10.1007/s00256-021-03769-w. PMID: 33792747

Value of intravoxel incoherent motion for differential diagnosis of renal tumors.

Zhu Q, Zhu W, Ye J, Wu J, Chen W, Hao Z
Acta Radiol 2019 Mar;60(3):382-387. Epub 2018 Jun 4 doi: 10.1177/0284185118778884. PMID: 29863413

Histologic Appearance After Preoperative Radiation Therapy for Soft Tissue Sarcoma: Assessment of the European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group Response Score.

Schaefer IM, Hornick JL, Barysauskas CM, Raut CP, Patel SA, Royce TJ, Fletcher CDM, Baldini EH
Int J Radiat Oncol Biol Phys 2017 Jun 1;98(2):375-383. Epub 2017 Feb 24 doi: 10.1016/j.ijrobp.2017.02.087. PMID: 28463157

See all (4)

Recent clinical studies

Etiology

Bone and soft tissue tumors at the borderlands of malignancy.

Crim J, Layfield LJ
Skeletal Radiol 2023 Mar;52(3):379-392. Epub 2022 Jun 29 doi: 10.1007/s00256-022-04099-1. PMID: 35767018

Pancreatic cancer: branched-chain amino acids as putative key metabolic regulators?

Rossmeislová L, Gojda J, Smolková K
Cancer Metastasis Rev 2021 Dec;40(4):1115-1139. Epub 2021 Dec 28 doi: 10.1007/s10555-021-10016-0. PMID: 34962613

The incidence and relevance of non-fatty components in trunk and extremity lipomatous soft tissue masses.

Berkeley R, Okereke O, Malhotra K, Saifuddin A
Br J Radiol 2021 Jun 1;94(1122):20201403. Epub 2021 May 20 doi: 10.1259/bjr.20201403. PMID: 33882249 Free PMC Article

Pazopanib in patients with advanced intermediate-grade or high-grade liposarcoma.

Chamberlain FE, Wilding C, Jones RL, Huang P
Expert Opin Investig Drugs 2019 Jun;28(6):505-511. Epub 2019 Apr 22 doi: 10.1080/13543784.2019.1607291. PMID: 31010343

Eribulin versus dacarbazine in previously treated patients with advanced liposarcoma or leiomyosarcoma: a randomised, open-label, multicentre, phase 3 trial.

Schöffski P, Chawla S, Maki RG, Italiano A, Gelderblom H, Choy E, Grignani G, Camargo V, Bauer S, Rha SY, Blay JY, Hohenberger P, D'Adamo D, Guo M, Chmielowski B, Le Cesne A, Demetri GD, Patel SR
Lancet 2016 Apr 16;387(10028):1629-37. Epub 2016 Feb 10 doi: 10.1016/S0140-6736(15)01283-0. PMID: 26874885

See all (89)

Diagnosis

Bone and soft tissue tumors at the borderlands of malignancy.

Crim J, Layfield LJ
Skeletal Radiol 2023 Mar;52(3):379-392. Epub 2022 Jun 29 doi: 10.1007/s00256-022-04099-1. PMID: 35767018

Management of adipose tumors in the limbs.

Le Nail LR, Crenn V, Rosset P, Ropars M
Orthop Traumatol Surg Res 2022 Feb;108(1S):103162. Epub 2021 Dec 1 doi: 10.1016/j.otsr.2021.103162. PMID: 34863958

Diagnosis strategy of adipocytic soft-tissue tumors in adults: a consensus from European experts.

Moulin B, Messiou C, Crombe A, Kind M, Hohenberger P, Rutkowski P, van Houdt WJ, Strauss D, Gronchi A, Bonvalot S
Eur J Surg Oncol 2022 Mar;48(3):518-525. Epub 2021 Oct 18 doi: 10.1016/j.ejso.2021.10.009. PMID: 34688512

The incidence and relevance of non-fatty components in trunk and extremity lipomatous soft tissue masses.

Berkeley R, Okereke O, Malhotra K, Saifuddin A
Br J Radiol 2021 Jun 1;94(1122):20201403. Epub 2021 May 20 doi: 10.1259/bjr.20201403. PMID: 33882249 Free PMC Article

Pediatric Fibroblastic and Myofibroblastic Tumors: A Pictorial Review.

Sargar KM, Sheybani EF, Shenoy A, Aranake-Chrisinger J, Khanna G
Radiographics 2016 Jul-Aug;36(4):1195-214. doi: 10.1148/rg.2016150191. PMID: 27399243

See all (97)

Therapy

Preoperative Muscle Strength Is a Predictor of Outcomes After Esophagectomy.

Colcord ME, Benbow JH, Trufan S, Gower NL, Byrne ME, Shea RE, Watson MD, Hill JS, Squires MH, Salo JC
J Gastrointest Surg 2021 Dec;25(12):3040-3048. Epub 2021 Nov 2 doi: 10.1007/s11605-021-05183-y. PMID: 34729696

Brown Adipose Tissue in Breast Cancer Evaluated by [(18)F] FDG-PET/CT.

Pace L, Nicolai E, Basso L, Garbino N, Soricelli A, Salvatore M
Mol Imaging Biol 2020 Aug;22(4):1111-1115. doi: 10.1007/s11307-020-01482-z. PMID: 32034622

Pazopanib in patients with advanced intermediate-grade or high-grade liposarcoma.

Chamberlain FE, Wilding C, Jones RL, Huang P
Expert Opin Investig Drugs 2019 Jun;28(6):505-511. Epub 2019 Apr 22 doi: 10.1080/13543784.2019.1607291. PMID: 31010343

Eribulin versus dacarbazine in previously treated patients with advanced liposarcoma or leiomyosarcoma: a randomised, open-label, multicentre, phase 3 trial.

Update on the use of aromatase inhibitors in breast cancer.

Brueggemeier RW
Expert Opin Pharmacother 2006 Oct;7(14):1919-30. doi: 10.1517/14656566.7.14.1919. PMID: 17020418

See all (30)

Prognosis

Pancreatic cancer: branched-chain amino acids as putative key metabolic regulators?

Rossmeislová L, Gojda J, Smolková K
Cancer Metastasis Rev 2021 Dec;40(4):1115-1139. Epub 2021 Dec 28 doi: 10.1007/s10555-021-10016-0. PMID: 34962613

The incidence and relevance of non-fatty components in trunk and extremity lipomatous soft tissue masses.

Berkeley R, Okereke O, Malhotra K, Saifuddin A
Br J Radiol 2021 Jun 1;94(1122):20201403. Epub 2021 May 20 doi: 10.1259/bjr.20201403. PMID: 33882249 Free PMC Article

Magnetic resonance imaging of trunk and extremity myxoid liposarcoma: diagnosis, staging, and response to treatment.

Saifuddin A, Andrei V, Rajakulasingam R, Oliveira I, Seddon B
Skeletal Radiol 2021 Oct;50(10):1963-1980. Epub 2021 Apr 1 doi: 10.1007/s00256-021-03769-w. PMID: 33792747

Diagnostic performance of MRI and histology in assessment of deep lipomatous tumours.

Cairncross L, Snow HA, Strauss DC, Smith MJF, Sjokvist O, Messiou C, Thway K, Hayes AJ
Br J Surg 2019 Dec;106(13):1794-1799. Epub 2019 Sep 10 doi: 10.1002/bjs.11309. PMID: 31502664

Pediatric Fibroblastic and Myofibroblastic Tumors: A Pictorial Review.

Sargar KM, Sheybani EF, Shenoy A, Aranake-Chrisinger J, Khanna G
Radiographics 2016 Jul-Aug;36(4):1195-214. doi: 10.1148/rg.2016150191. PMID: 27399243

See all (67)

Clinical prediction guides

A CT-based radiomics classification model for the prediction of histological type and tumour grade in retroperitoneal sarcoma (RADSARC-R): a retrospective multicohort analysis.

Arthur A, Orton MR, Emsley R, Vit S, Kelly-Morland C, Strauss D, Lunn J, Doran S, Lmalem H, Nzokirantevye A, Litiere S, Bonvalot S, Haas R, Gronchi A, Van Gestel D, Ducassou A, Raut CP, Meeus P, Spalek M, Hatton M, Le Pechoux C, Thway K, Fisher C, Jones R, Huang PH, Messiou C
Lancet Oncol 2023 Nov;24(11):1277-1286. doi: 10.1016/S1470-2045(23)00462-X. PMID: 37922931 Free PMC Article

Brown Adipose Tissue in Breast Cancer Evaluated by [(18)F] FDG-PET/CT.

Pace L, Nicolai E, Basso L, Garbino N, Soricelli A, Salvatore M
Mol Imaging Biol 2020 Aug;22(4):1111-1115. doi: 10.1007/s11307-020-01482-z. PMID: 32034622

Clinical characteristics and surgical outcomes of retroperitoneal tumors: a comprehensive data collection from multiple departments.

Sassa N, Yokoyama Y, Nishida Y, Yamada S, Uchida H, Kajiyama H, Nagino M, Kodera Y, Gotoh M
Int J Clin Oncol 2020 May;25(5):929-936. Epub 2020 Jan 16 doi: 10.1007/s10147-020-01620-1. PMID: 31950376

MR findings of the osteofibrous dysplasia.

Jung JY, Jee WH, Hong SH, Kang HS, Chung HW, Ryu KN, Kim JY, Im SA, Park JM, Sung MS, Lee YS, Hong SJ, Jung CK, Chung YG
Korean J Radiol 2014 Jan-Feb;15(1):114-22. Epub 2014 Jan 8 doi: 10.3348/kjr.2014.15.1.114. PMID: 24497800 Free PMC Article

An electron microscopic study of hepatic angiomyolipoma.

Okada K, Yokoyama S, Nakayama I, Tada I, Kobayashi M
Acta Pathol Jpn 1989 Nov;39(11):743-9. doi: 10.1111/j.1440-1827.1989.tb02424.x. PMID: 2694755

See all (65)

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Intermediate Lipomatous Neoplasm

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Supplemental Content

Table of contents

Practice guidelines

Related information

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