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Benign Pilar-Associated Mesenchyme Neoplasm

MedGen UID:: 312919
•Concept ID:: C1706925
•: Neoplastic Process

Synonym:

Benign Pilar-Associated Mesenchyme Tumor

Definition

A mesenchymal neoplasm arising from the pilar sheath of the hair follicle. It is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. Representative examples include fibrofolliculoma, perifollicular fibroma, pilar leiomyoma, and trichogenic myxoma. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVBenign Pilar-Associated Mesenchyme Neoplasm

Neoplasm
- Neoplasm by Special Category
  - Benign neoplasm
    - Benign neoplasm of skin
      - Benign Skin Appendage Neoplasm
        Benign Hair Follicle Neoplasm
        Benign Pilar-Associated Mesenchyme Neoplasm
        Fibrofolliculoma
        Follicular Myxoma
        Perifollicular fibroma
        Pilar Leiomyoma
        Trichodiscoma

Professional guidelines

PubMed

Cardiac myxomas: clinical presentation, diagnosis and management.

Griborio-Guzman AG, Aseyev OI, Shah H, Sadreddini M
Heart 2022 May 12;108(11):827-833. doi: 10.1136/heartjnl-2021-319479. PMID: 34493547

Overview of primary adult retroperitoneal tumours.

Improta L, Tzanis D, Bouhadiba T, Abdelhafidh K, Bonvalot S
Eur J Surg Oncol 2020 Sep;46(9):1573-1579. Epub 2020 May 21 doi: 10.1016/j.ejso.2020.04.054. PMID: 32600897

Clinical presentation, diagnostic approach, and treatment of hand lipomas: a review.

Lichon S, Khachemoune A
Acta Dermatovenerol Alp Pannonica Adriat 2018 Sep;27(3):137-139. PMID: 30244263

See all (72)

Recent clinical studies

Etiology

What's new in adipocytic neoplasia?

Thway K
Histopathology 2022 Jan;80(1):76-97. doi: 10.1111/his.14548. PMID: 34958506

Chondrosarcoma.

Weinschenk RC, Wang WL, Lewis VO
J Am Acad Orthop Surg 2021 Jul 1;29(13):553-562. doi: 10.5435/JAAOS-D-20-01188. PMID: 33595238

Pathology of meningiomas.

Solomon DA, Pekmezci M
Handb Clin Neurol 2020;169:87-99. doi: 10.1016/B978-0-12-804280-9.00005-6. PMID: 32553300

Uterine fibroids in menopause and perimenopause.

Ulin M, Ali M, Chaudhry ZT, Al-Hendy A, Yang Q
Menopause 2020 Feb;27(2):238-242. doi: 10.1097/GME.0000000000001438. PMID: 31834160 Free PMC Article

Cartilage-forming tumors.

Qasem SA, DeYoung BR
Semin Diagn Pathol 2014 Jan;31(1):10-20. Epub 2014 Jan 23 doi: 10.1053/j.semdp.2014.01.006. PMID: 24680178

See all (823)

Diagnosis

Ameloblastic Fibro-Odontoma.

Safavi M, Mohammadi F
Fetal Pediatr Pathol 2023 Apr;42(2):281-284. Epub 2022 Jun 24 doi: 10.1080/15513815.2022.2088910. PMID: 35748698

Intramuscular Eyelid Myxoma.

Liu CK, Williamson JE 3rd, Milman T, Lally SE, Shields CL
Ophthalmic Plast Reconstr Surg 2022 Nov-Dec 01;38(6):e180-e183. Epub 2022 Jul 4 doi: 10.1097/IOP.0000000000002236. PMID: 35793663

Atypical Fibroxanthoma Revisited.

Mentzel T, Requena L, Brenn T
Surg Pathol Clin 2017 Jun;10(2):319-335. Epub 2017 Mar 14 doi: 10.1016/j.path.2017.01.007. PMID: 28477883

Dermatomyofibroma.

Campagnolo OA, Morais CF, Ughini MO, Aoki CM, Menegazzo M
An Bras Dermatol 2017 Jan-Feb;92(1):101-103. doi: 10.1590/abd1806-4841.20175189. PMID: 28225965 Free PMC Article

Paraurethral leiomyoma.

Perugia G, Ciccariello M, Pirolli F, Chinazzi A, Teodonio S, Borgoni G, Croce F, Liberti M
Urology 2012 Apr;79(4):e51-2. Epub 2011 Oct 19 doi: 10.1016/j.urology.2011.08.004. PMID: 22014968

See all (2074)

Therapy

Tumor-Induced Osteomalacia.

Florenzano P, Hartley IR, Jimenez M, Roszko K, Gafni RI, Collins MT
Calcif Tissue Int 2021 Jan;108(1):128-142. Epub 2020 Jun 5 doi: 10.1007/s00223-020-00691-6. PMID: 32504138

Metaplastic carcinoma of the breast.

McKinnon E, Xiao P
Arch Pathol Lab Med 2015 Jun;139(6):819-22. doi: 10.5858/arpa.2013-0358-RS. PMID: 26030252

Gastrointestinal stromal tumour.

Joensuu H, Hohenberger P, Corless CL
Lancet 2013 Sep 14;382(9896):973-83. Epub 2013 Apr 24 doi: 10.1016/S0140-6736(13)60106-3. PMID: 23623056

Angioadnexocentric nevus.

Hashimoto K, Amano M, Setoyama M
J Dermatol 2012 Nov;39(11):909-15. Epub 2012 Jul 4 doi: 10.1111/j.1346-8138.2012.01599.x. PMID: 22762690

Liver tumors.

Stringer MD
Semin Pediatr Surg 2000 Nov;9(4):196-208. doi: 10.1053/spsu.2000.18844. PMID: 11112837

See all (147)

Prognosis

Intramuscular Eyelid Myxoma.

Liu CK, Williamson JE 3rd, Milman T, Lally SE, Shields CL
Ophthalmic Plast Reconstr Surg 2022 Nov-Dec 01;38(6):e180-e183. Epub 2022 Jul 4 doi: 10.1097/IOP.0000000000002236. PMID: 35793663

Cardiac myxomas: clinical presentation, diagnosis and management.

Griborio-Guzman AG, Aseyev OI, Shah H, Sadreddini M
Heart 2022 May 12;108(11):827-833. doi: 10.1136/heartjnl-2021-319479. PMID: 34493547

Chondrosarcoma.

Weinschenk RC, Wang WL, Lewis VO
J Am Acad Orthop Surg 2021 Jul 1;29(13):553-562. doi: 10.5435/JAAOS-D-20-01188. PMID: 33595238

Uterine Adenosarcoma.

Pinto A, Howitt B
Arch Pathol Lab Med 2016 Mar;140(3):286-90. doi: 10.5858/arpa.2014-0523-RS. PMID: 26927725

Placental chorioangioma: literature review.

Fan M, Skupski DW
J Perinat Med 2014 May;42(3):273-9. doi: 10.1515/jpm-2013-0170. PMID: 24334427

See all (853)

Clinical prediction guides

Clinical and pathomorphological aspects of odontogenic tumors.

Gültekin SE, Büttner R
Pathologie (Heidelb) 2022 Aug;43(Suppl 1):86-93. Epub 2022 Nov 8 doi: 10.1007/s00292-022-01150-9. PMID: 36346463

Oral Adult Rhabdomyoma.

da Silva Leonel ACL, Dos Santos ST, de Amorim Carvalho EJ, de Castro JFL, de Almeida OP, da Cruz Perez DE
Head Neck Pathol 2021 Dec;15(4):1253-1260. Epub 2021 Aug 10 doi: 10.1007/s12105-021-01371-z. PMID: 34378165 Free PMC Article

Chondroma of the Tongue.

Dimitrijevic MV, Sopta J, Ivisevic TB, Dudvarski Z
J Craniofac Surg 2019 Jun;30(4):e315-e317. doi: 10.1097/SCS.0000000000005230. PMID: 30845089

Non-epithelial neoplasms of the prostate.

Paner GP, Aron M, Hansel DE, Amin MB
Histopathology 2012 Jan;60(1):166-86. doi: 10.1111/j.1365-2559.2011.04020.x. PMID: 22212085

Uterine pseudotumors.

Simionescu C, Mărgăritescu C, Stepan A, Ciurea R, Cernea N
Rom J Morphol Embryol 2011;52(3):743-58. PMID: 21892515

See all (664)

Recent systematic reviews

Prevalence of BRAF p.V600E and Detection Methods in Benign Mixed and Malignant Odontogenic Tumors: A Systematic Review.

Severino-Lazo RJG, de Vasconcelos Carvalho M, Campello CP, Moraes SLD, do Egito Vasconcelos BC, Pellizzer EP
Head Neck Pathol 2023 Dec;17(4):1000-1010. Epub 2023 Dec 6 doi: 10.1007/s12105-023-01601-6. PMID: 38057461 Free PMC Article

Tumor-induced Osteomalacia: A Systematic Review and Individual Patient's Data Analysis.

Rendina D, Abate V, Cacace G, D'Elia L, De Filippo G, Del Vecchio S, Galletti F, Cuocolo A, Strazzullo P
J Clin Endocrinol Metab 2022 Jul 14;107(8):e3428-e3436. doi: 10.1210/clinem/dgac253. PMID: 35468192

Esophageal Lipoma and Liposarcoma: A Systematic Review.

Ferrari D, Bernardi D, Siboni S, Lazzari V, Asti E, Bonavina L
World J Surg 2021 Jan;45(1):225-234. Epub 2020 Oct 7 doi: 10.1007/s00268-020-05789-4. PMID: 33026474 Free PMC Article

Primordial odontogenic tumor: A systematic review.

Bologna-Molina R, Pereira-Prado V, Sánchez-Romero C, González-González R, Mosqueda-Taylor A
Med Oral Patol Oral Cir Bucal 2020 May 1;25(3):e388-e394. doi: 10.4317/medoral.23432. PMID: 32040459 Free PMC Article

Management of hepatic angiomyolipoma: A systematic review.

Klompenhouwer AJ, Verver D, Janki S, Bramer WM, Doukas M, Dwarkasing RS, de Man RA, IJzermans JNM
Liver Int 2017 Sep;37(9):1272-1280. Epub 2017 Mar 6 doi: 10.1111/liv.13381. PMID: 28177188

See all (13)

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