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Meningoencephalitis

MedGen UID:
6301
Concept ID:
C0025309
Disease or Syndrome
Synonyms: Cerebromeningitides; Cerebromeningitis; Encephalomeningitides; Encephalomeningitis; Meningoencephalitides
SNOMED CT: Meningoencephalitis (7125002)
 
Monarch Initiative: MONDO:0005845

Definition

Inflammation of the meninges and brain, generally secondary to an infectious cause. Pathogens may be bacterial, viral, fungal, or protozoan. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Vairo F, Haider N, Kock R, Ntoumi F, Ippolito G, Zumla A
Infect Dis Clin North Am 2019 Dec;33(4):1003-1025. doi: 10.1016/j.idc.2019.08.006. PMID: 31668189
Lynch JP 3rd, Kajon AE
Semin Respir Crit Care Med 2016 Aug;37(4):586-602. Epub 2016 Aug 3 doi: 10.1055/s-0036-1584923. PMID: 27486739Free PMC Article
Grace E, Asbill S, Virga K
Antimicrob Agents Chemother 2015 Nov;59(11):6677-81. Epub 2015 Aug 10 doi: 10.1128/AAC.01293-15. PMID: 26259797Free PMC Article

Recent clinical studies

Etiology

Haston JC, Cope JR
Curr Opin Infect Dis 2023 Jun 1;36(3):186-191. Epub 2023 Apr 10 doi: 10.1097/QCO.0000000000000923. PMID: 37093056Free PMC Article
Succar EF, Turner JH, Chandra RK
Int Forum Allergy Rhinol 2019 May;9(S1):S4-S8. doi: 10.1002/alr.22330. PMID: 31087631
Messacar K, Fischer M, Dominguez SR, Tyler KL, Abzug MJ
Infect Dis Clin North Am 2018 Mar;32(1):145-162. Epub 2017 Dec 8 doi: 10.1016/j.idc.2017.10.007. PMID: 29224854Free PMC Article
Fang B, McKeon A, Hinson SR, Kryzer TJ, Pittock SJ, Aksamit AJ, Lennon VA
JAMA Neurol 2016 Nov 1;73(11):1297-1307. doi: 10.1001/jamaneurol.2016.2549. PMID: 27618707
Lanska DJ
Neurology 2002 Aug 13;59(3):327-34. doi: 10.1212/wnl.59.3.327. PMID: 12177364

Diagnosis

Thy M, de Montmollin E, Bouadma L, Timsit JF, Sonneville R
Curr Opin Crit Care 2023 Oct 1;29(5):415-422. Epub 2023 Aug 9 doi: 10.1097/MCC.0000000000001087. PMID: 37641514
Rojo JU, Rajendran R, Salazar JH
Lab Med 2023 Sep 5;54(5):e124-e132. doi: 10.1093/labmed/lmac158. PMID: 36638160
Chadwick DR
Br Med Bull 2005;75-76:1-14. Epub 2006 Feb 10 doi: 10.1093/bmb/ldh057. PMID: 16474042
Lanska DJ
Neurology 2002 Aug 13;59(3):327-34. doi: 10.1212/wnl.59.3.327. PMID: 12177364
Martin RA, Bates D, Shaw DA
Br Med J 1975 Jul 12;3(5975):75-6. doi: 10.1136/bmj.3.5975.75. PMID: 1095135Free PMC Article

Therapy

Caffes N, Hendricks K, Bradley JS, Twenhafel NA, Simard JM
Clin Infect Dis 2022 Oct 17;75(Suppl 3):S451-S458. doi: 10.1093/cid/ciac521. PMID: 36251558Free PMC Article
Stott KE, Loyse A, Jarvis JN, Alufandika M, Harrison TS, Mwandumba HC, Day JN, Lalloo DG, Bicanic T, Perfect JR, Hope W
Lancet Infect Dis 2021 Sep;21(9):e259-e271. Epub 2021 Apr 16 doi: 10.1016/S1473-3099(20)30771-4. PMID: 33872594
Cheong TZ, Davies RP
Ophthalmic Plast Reconstr Surg 2019 Mar/Apr;35(2):e47-e49. doi: 10.1097/IOP.0000000000001324. PMID: 30730432
Chadwick DR
Br Med Bull 2005;75-76:1-14. Epub 2006 Feb 10 doi: 10.1093/bmb/ldh057. PMID: 16474042
Martin RA, Bates D, Shaw DA
Br Med J 1975 Jul 12;3(5975):75-6. doi: 10.1136/bmj.3.5975.75. PMID: 1095135Free PMC Article

Prognosis

Rojo JU, Rajendran R, Salazar JH
Lab Med 2023 Sep 5;54(5):e124-e132. doi: 10.1093/labmed/lmac158. PMID: 36638160
Carod-Artal FJ
Expert Rev Anti Infect Ther 2018 May;16(5):399-410. Epub 2018 Apr 26 doi: 10.1080/14787210.2018.1466702. PMID: 29668332
Nascimento OJM, da Silva IRF
Curr Opin Neurol 2017 Oct;30(5):500-507. doi: 10.1097/WCO.0000000000000471. PMID: 28617719
Lanska DJ
Neurology 2002 Aug 13;59(3):327-34. doi: 10.1212/wnl.59.3.327. PMID: 12177364
Hadfield MG, Aydin F, Lippman HR, Sanders KM
Clin Neuropathol 1997 Mar-Apr;16(2):55-60. PMID: 9101104

Clinical prediction guides

Sonneville R, de Montmollin E, Contou D, Ferrer R, Gurjar M, Klouche K, Sarton B, Demeret S, Bailly P, da Silva D, Escudier E, Le Guennec L, Chabanne R, Argaud L, Ben Hadj Salem O, Thyrault M, Frerou A, Louis G, De Pascale G, Horn J, Helbok R, Geri G, Bruneel F, Martin-Loeches I, Taccone FS, De Waele JJ, Ruckly S, Staiquly Q, Citerio G, Timsit JF; EURECA Investigator Study Group
Intensive Care Med 2023 May;49(5):517-529. Epub 2023 Apr 6 doi: 10.1007/s00134-023-07032-9. PMID: 37022378
Clé M, Beck C, Salinas S, Lecollinet S, Gutierrez S, Van de Perre P, Baldet T, Foulongne V, Simonin Y
Epidemiol Infect 2019 Jan;147:e232. doi: 10.1017/S0950268819001213. PMID: 31364580Free PMC Article
Wang YH, Zhang YG
Immunobiology 2018 Mar;223(3):288-293. Epub 2017 Oct 16 doi: 10.1016/j.imbio.2017.10.038. PMID: 29070439
Charlier C, Perrodeau É, Leclercq A, Cazenave B, Pilmis B, Henry B, Lopes A, Maury MM, Moura A, Goffinet F, Dieye HB, Thouvenot P, Ungeheuer MN, Tourdjman M, Goulet V, de Valk H, Lortholary O, Ravaud P, Lecuit M; MONALISA study group
Lancet Infect Dis 2017 May;17(5):510-519. Epub 2017 Jan 28 doi: 10.1016/S1473-3099(16)30521-7. PMID: 28139432
Fang B, McKeon A, Hinson SR, Kryzer TJ, Pittock SJ, Aksamit AJ, Lennon VA
JAMA Neurol 2016 Nov 1;73(11):1297-1307. doi: 10.1001/jamaneurol.2016.2549. PMID: 27618707

Recent systematic reviews

Zhang M, Wang H, Tang J, He Y, Xiong T, Li W, Qu Y, Mu D
BMC Pediatr 2021 Mar 15;21(1):127. doi: 10.1186/s12887-021-02599-y. PMID: 33722228Free PMC Article
Velasco R, Villagrán M, Jové M, Simó M, Vilariño N, Alemany M, Palmero R, Martínez-Villacampa MM, Nadal E, Bruna J
JAMA Neurol 2021 Jul 1;78(7):864-873. doi: 10.1001/jamaneurol.2021.0249. PMID: 33720308
Mondal R, Ganguly U, Deb S, Shome G, Pramanik S, Bandyopadhyay D, Lahiri D
J Neurovirol 2021 Feb;27(1):12-25. Epub 2020 Dec 26 doi: 10.1007/s13365-020-00923-3. PMID: 33367960Free PMC Article
Córdova E, Maiolo E, Corti M, Orduña T
Neurol Res 2010 Apr;32(3):238-44. doi: 10.1179/016164110X12644252260637. PMID: 20406601
Rafailidis PI, Mourtzoukou EG, Varbobitis IC, Falagas ME
Virol J 2008 Mar 27;5:47. doi: 10.1186/1743-422X-5-47. PMID: 18371229Free PMC Article

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