U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Adult Rickets

MedGen UID:
854493
•Concept ID:
C3887650
•
Disease or Syndrome
Synonyms: Osteomalacia; Rickets, Adult

Definition

Disorder caused by an interruption of the mineralization of organic bone matrix leading to bone softening, bone pain, and weakness. It is the adult form of rickets resulting from disruption of VITAMIN D; PHOSPHORUS; or CALCIUM homeostasis. [from MeSH]

Professional guidelines

PubMed

Clinical practice recommendations for the diagnosis and management of X-linked hypophosphataemia.
Haffner D, Emma F, Eastwood DM, Duplan MB, Bacchetta J, Schnabel D, Wicart P, Bockenhauer D, Santos F, Levtchenko E, Harvengt P, Kirchhoff M, Di Rocco F, Chaussain C, Brandi ML, Savendahl L, Briot K, Kamenicky P, Rejnmark L, Linglart A
Nat Rev Nephrol 2019 Jul;15(7):435-455. doi: 10.1038/s41581-019-0152-5. PMID: 31068690Free PMC Article
The vitamin D deficiency pandemic: Approaches for diagnosis, treatment and prevention.
Holick MF
Rev Endocr Metab Disord 2017 Jun;18(2):153-165. doi: 10.1007/s11154-017-9424-1. PMID: 28516265
Global Consensus Recommendations on Prevention and Management of Nutritional Rickets.
Munns CF, Shaw N, Kiely M, Specker BL, Thacher TD, Ozono K, Michigami T, Tiosano D, Mughal MZ, Mäkitie O, Ramos-Abad L, Ward L, DiMeglio LA, Atapattu N, Cassinelli H, Braegger C, Pettifor JM, Seth A, Idris HW, Bhatia V, Fu J, Goldberg G, Sävendahl L, Khadgawat R, Pludowski P, Maddock J, Hyppönen E, Oduwole A, Frew E, Aguiar M, Tulchinsky T, Butler G, Högler W
J Clin Endocrinol Metab 2016 Feb;101(2):394-415. Epub 2016 Jan 8 doi: 10.1210/jc.2015-2175. PMID: 26745253Free PMC Article

Recent clinical studies

Etiology

Renal tubular acidosis, Sjögren syndrome, and bone disease.
Fulop M, Mackay M
Arch Intern Med 2004 Apr 26;164(8):905-9. doi: 10.1001/archinte.164.8.905. PMID: 15111378

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...