In this model the values of "free CDK" (Id: x2), "cdc25_P" (x4) "Wee1_P" (Id: y5) and "APC" (Id: y6) are assigned using the parameters describing the total concentrations totcdk (Id: c)), totcdc5, totwee1 and totAPC. So if you want to change the levels of these proteins, you need to change the values ofthese parameters.
This model originates from BioModels Database: A Database of Annotated Published Models. It is copyright (c) 2005-2010 The BioModels Team.
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Le Novère N., Bornstein B., Broicher A., Courtot M., Donizelli M., Dharuri H., Li L., Sauro H., Schilstra M., Shapiro B., Snoep J.L., Hucka M. (2006) BioModels Database: A Free, Centralized Database of Curated, Published, Quantitative Kinetic Models of Biochemical and Cellular Systems Nucleic Acids Res., 34: D689-D691.
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A simple time delay model for eukaryotic cell cycle.
- J Srividhya, M S Gopinathan
- Journal of theoretical biology , 8/ 2006 , Volume 241 , Issue 3 , pages: 617-627 , PubMed ID: 16473373
Submitter of this revision: Lucian Smith
Curator: Lucian Smith
Modeller: Harish Dharuri
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