Nazaret2009_TCA_RC_ATP

Model Identifier
BIOMD0000000232
Short description

This a model from the article:
Mitochondrial energetic metabolism: a simplified model of TCA cycle with ATP production.
Nazaret C, Heiske M, Thurley K, Mazat JP J. Theor. Biol. 2009 Jun;258(3):455-64 19007794 ,
Abstract:
Mitochondria play a central role in cellular energetic metabolism. The essential parts of this metabolism are the tricarboxylic acid (TCA) cycle, the respiratory chain and the adenosine triphosphate (ATP) synthesis machinery. Here a simplified model of these three metabolic components with a limited set of differential equations is presented. The existence of a steady state is demonstrated and results of numerical simulations are presented. The relevance of a simple model to represent actual in vivo behavior is discussed.

Format
SBML (L2V4)
Related Publication
  • Mitochondrial energetic metabolism: a simplified model of TCA cycle with ATP production.
  • Christine Nazaret, Margit Heiske, Kevin Thurley, Jean-Pierre Mazat
  • Journal of theoretical biology , 6/ 2009 , Volume 258 , Issue 3 , pages: 455-464 , PubMed ID: 19007794
Contributors
Submitter of the first revision: Kieran Smallbone
Submitter of this revision: Lucian Smith
Curator: Lucian Smith
Modeller: Kieran Smallbone

Metadata information

is (2 statements)
BioModels Database BIOMD0000000232
BioModels Database MODEL2594602728

isDescribedBy (1 statement)
PubMed 19007794

hasTaxon (1 statement)
Taxonomy Homo sapiens

hasVersion (4 statements)
isPartOf (3 statements)
hasProperty (1 statement)
Mathematical Modelling Ontology Ordinary differential equation model


Curation status
Curated


Connected external resources